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@susiemclaren

Developmental biologist, interested in ecosystem interactions - working on the development of coral-algae symbiosis.

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08.11.2023
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Latest posts by @susiemclaren

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A stoplight parrotfish heralds the arrival of the squid squad while a striped parrotfish sees them out πŸš¦πŸ¦œπŸŸπŸ¦‘πŸ¦‘πŸ¦‘πŸ³οΈβ€βš§οΈπŸ¦œπŸŸ #squidsquad #cephalopodsofcoralcity #stoplightparrotfish #stripedparrotfish #coralcitycamera

11.02.2026 17:18 πŸ‘ 327 πŸ” 60 πŸ’¬ 6 πŸ“Œ 5

Very cool

26.11.2025 10:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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In this week's DB unit seminar @embl.org, Eva Pillai @evapillai.bsky.social , a postdoc in the Arendt, Diz-MuΓ±oz @diz-lab.bsky.social and Brunet groups @thibautbrunet.bsky.social , shared insights on the role of cell surface mechanics in multicellularity, using choanoflagellates as a model organism

20.11.2025 07:52 πŸ‘ 16 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture Reconstituting 20-kb chromatin shows that tuning acetylation alone reshapes its folding, dynamics, and contact domain formation.

To probe gene-scale chromatin physics, we built 96-mer (20 kb) arrays with defined histone marks. Combining single-molecule tracking, AFM imaging, and developing in vitro Hi-C, we saw how specific modifications dictate chromatin structure and dynamics. www.science.org/doi/10.1126/...

20.11.2025 07:46 πŸ‘ 60 πŸ” 21 πŸ’¬ 5 πŸ“Œ 1
Reversing defaunation through rewilding and its consequences for biodiversity and ecosystem function | Department of Zoology Reversing defaunation through rewilding and its consequences for biodiversity and ecosystem function Supervisor: Professor Rob Fletcher The world is facing several global challenges that are transform...

Please repost!

I am looking for a passionate and hard-working PhD student to work in southern Africa on experimental defaunation and rewilding of megafauna. See the link below for more information:

@camzoology.bsky.social @conservation.cam.ac.uk

29.10.2025 08:46 πŸ‘ 8 πŸ” 13 πŸ’¬ 0 πŸ“Œ 1
Developmental Biology and Disability - the Node Hopeful monsters. Morphospace. Mutation. Natural variation. Mutagenesis screens. Polymorphism. Deformity. Phenotype. Disease. Adaptation. Anomaly.

I wrote something on developmental biology and disability and put it up on the node last night:

thenode.biologists.com/developmenta...

I've been nervous to share because some of it veers a bit personal but they are thoughts that won't stay quiet. Would love to know what people think about it!

30.09.2025 09:38 πŸ‘ 39 πŸ” 19 πŸ’¬ 6 πŸ“Œ 3
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Call for abstracts now open at: www.icrs2026.nz/call-for-abs...

Submissions are invited under approved sessions aligned eight broad Symposium themes.

You may submit an abstract as:
- Oral presentation
- Speed talk
- Poster

Deadline: Monday 1 December 2025, 11.59pm (New Zealand time).

18.09.2025 19:17 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

Wow these are so beautiful!

17.09.2025 08:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Spotted moray slithering through the morning traffic in Coral City! #spottedmoray #moray #thatsamoray #morayeel #schoolmaster #snapper #stripedparrotfish #parrotfishjungle #coral #coralhead #coralcitycamera #miami #portmiami #miamibeach #biscaynebay #coralcity

14.08.2025 15:18 πŸ‘ 1185 πŸ” 164 πŸ’¬ 13 πŸ“Œ 19
Meeting and attendee details with a backdrop of Chicago, with an invitation to meet the deepmirror team at booth #16

Meeting and attendee details with a backdrop of Chicago, with an invitation to meet the deepmirror team at booth #16

@deepmirror.bsky.social is heading to Chicago for @acsmedi.bsky.social & @euromedchem.bsky.social Medicinal Chemistry Frontiers 2025! πŸ™οΈ

If you’re also attending or happen to be in the Chicago area, I’d love to connect. Drop me a message or visit us at Booth 16 - let’s grab a β˜• and πŸ’¬!

13.05.2025 10:29 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Re-posts appreciated!

We have an open PhD position w/ Prof Harold Auradou on #microswimmers/#protists in complex media! Students get to spend at least 12 months in Paris, and will receive their PhD from both Exeter and Paris-Saclay!

Apply by 31st Mar.
More details:
adum.fr/as/ed/voirpr...

04.03.2025 21:29 πŸ‘ 29 πŸ” 38 πŸ’¬ 2 πŸ“Œ 1

Congrats!

05.03.2025 17:01 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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David Ish-Horowicz FRS (1948-2024): outstanding scientific discovery, with a unique touch of selfless humanity David as a young graduate student at the LMB (MRC Laboratory of Molecular Biology, University of Cambridge).David Ish-Horowicz, affectionately known as β€˜David Ish’ or just β€˜Ish’ (β€˜man’ in Hebrew), die...

Here is my obituary to my PhD supervisor and close friend David Ish-Horowicz, a lovely supportive mentor and friend for many generations of scientists and spent 10 years in my lab after β€œretiring”. We will all miss him.

Development (2024) 151 (21): dev204429.
doi.org/10.1242/dev....

25.10.2024 10:22 πŸ‘ 18 πŸ” 10 πŸ’¬ 3 πŸ“Œ 0
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Happy Friday! Here's an #Aiptasia polyp from this week's adventure into Cnidarian - Plankton #symbiosis

01.03.2024 11:03 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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We were blessed with an hour of squid courtship flashing on cam today πŸ¦‘πŸ’žπŸ¦‘ www.instagram.com/p/C3T9aVOue_...

14.02.2024 03:04 πŸ‘ 111 πŸ” 14 πŸ’¬ 0 πŸ“Œ 1

All of this work was done using the early chicken embryo as a model system.

12.02.2024 11:12 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Thanks to everyone in the Xiong group, for the great support of our core facility teams at the Gurdon Institute and for funding from the Wellcome Trust and UKRI.

12.02.2024 10:59 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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This leads us to propose a model of early brain and spinal cord shape divergence, where differential mechanical properties regulated by neural crest mediated matrix remodelling facilitate brain expansion relative to the spinal cord under a positive neural tube lumen pressure.

12.02.2024 10:57 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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By grafting a small patch of cells from the dorsal hindbrain to the dorsal spinal cord in early embryos and allowing them to develop, we found that dorsal hindbrain cells were sufficient to create a brain-like morphology with a thinned out dorsal roof in the spinal cord.

12.02.2024 10:56 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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We blocked the activity of matrix metalloproteases that neural crest cells use to remodel the matrix and found that brain expansion was inhibited. This suggested matrix remodelling played a key role in fluidising the dorsal hindbrain, allowing it to deform under lumen pressure.

12.02.2024 10:56 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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This difference in matrix organisation occurred within the snail2+ premigratory neural crest domain of the neural tube.

12.02.2024 10:55 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Why might this be? We investigated extracellular matrix organisation as it plays an important role in determining a tissue’s material properties and found that matrix organisation differed between the dorsal hindbrain and spinal cord.

12.02.2024 10:55 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Using ferrofluid droplets, theoretical modelling and atomic force microscopy, we found that the dorsal hindbrain is more fluid than the dorsal spinal cord prior to brain expansion.

12.02.2024 10:54 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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The neural tube, the embryonic precursor of the central nervous system, has a positive internal fluid pressure (Desmond et al. 2005). By modulating the pressure we found that it drives hindbrain dorsal tissue thinning and expansion, whilst the spinal cord holds its shape.

12.02.2024 10:52 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Very happy to share a preprint of our work investigating how the embryonic brain expands and departs in morphology from the spinal cord early in development. Great to collaborate with @ehannezo.bsky.social Shi-Lei Xue, Kristian Franze and Alex Winkel on this.

-> doi.org/10.1101/2024...

12.02.2024 10:52 πŸ‘ 9 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0

Congratulations!

15.11.2023 17:38 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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'Tis the season...for #fungi πŸ„πŸ“· Orange one is Yellow Stagshorn, not sure about the others

09.11.2023 09:23 πŸ‘ 19 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0