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Wil Furnon

@wfurnon

Virologist - Coronaviruses and other respiratory viruses, virus-host interactions. Views my own

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05.01.2025
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Latest posts by Wil Furnon @wfurnon

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Lab Manager at University of Glasgow Explore an exciting academic career as a Lab Manager. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

🚨🚨🚨Lab manager position available in the Maizels lab: great team, super exciting project!
🚧 Deadline to apply: 14th May
More details below
www.jobs.ac.uk/job/DMV729/l...

29.04.2025 20:30 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Antibody escape drives emergence of diverse spike haplotypes resembling variants of concern in persistent SARS-CoV-2 infections Evolution of SARS-CoV-2 in long-term persistent infections is hypothesised to be a major source of variants of concern (VOC). However, the linkage of intra-host variants into haplotypes that reflect v...

New preprint from Luke Snell from GSTT, Suzanne Pickering in my lab and Rui Galao, my colleague at KCL.

Here we examine in detail the evolution of the SARS CoV-2 spike in persistent infections, and essentially catch a potential variant in the act of developing. 1/n

www.biorxiv.org/content/10.1...

23.04.2025 06:42 πŸ‘ 80 πŸ” 42 πŸ’¬ 2 πŸ“Œ 4
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We're strengthening the nation’s health security defences. πŸ›‘
Live from #UKHSA25, we've announced a new tool to help focus research efforts on pathogen families of greatest potential risk to public health, boosting preparedness against future threats.
πŸ“°πŸ”— www.gov.uk/government/n...

25.03.2025 10:16 πŸ‘ 21 πŸ” 10 πŸ’¬ 2 πŸ“Œ 3
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Polymerase mutations underlie adaptation of H5N1 influenza virus to dairy cattle and other mammals. In early 2024, an unprecedented outbreak of H5N1 high pathogenicity avian influenza was detected in dairy cattle in the USA. The epidemic remains uncontrolled, with spillbacks into poultry, wild birds...

Really proud to share our preprint describing early adaptation of H5N1 to US dairy cattle, and showing how these mutations enhance the ability of the virus to infect other mammals, such as pigs and humans.

With @influenzal.bsky.social @vidhid.bsky.social @drclairesmith.bsky.social and many more!

07.01.2025 07:59 πŸ‘ 350 πŸ” 158 πŸ’¬ 9 πŸ“Œ 15

A huge thanks to @serdelor.bsky.social (best buddy ever), @grovearmada.bsky.social , @davidlrobertson.bsky.social and many others!

05.01.2025 14:43 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic - Nature Microbiology Systematic comparison of SARS-CoV-2 spike proteins from pre- and post-Omicron variants in cell lines, primary respiratory epithelial cells and Syrian hamsters show distinct phenotypic trajectories in ...

πŸš¨πŸ”” Delighted to see this piece of work from @cvrinfo.bsky.social now out in @naturemicrobiol.bsky.social ! Indeed, it really reflects what multidisciplinary team effort can be. Guess what? Spike of #SARSCoV2 is not just about antigenicity/immune evasion… doi.org/10.1038/s415...

05.01.2025 14:43 πŸ‘ 18 πŸ” 12 πŸ’¬ 1 πŸ“Œ 3