sho's Avatar

sho

@shoyip

physics of complex systems. biophys, biochem, biomol. florence / rome / paris.

84
Followers
687
Following
68
Posts
26.10.2023
Joined
Posts Following

Latest posts by sho @shoyip

Video thumbnail

This isn’t about left versus right.

It’s about science versus pseudoscience.

- Dr. Jessica Knurick

23.09.2025 22:24 👍 179 🔁 73 💬 5 📌 7
A larger than softball sized grapefruit my 13 inexplicably brought home to try, with googly eyes stuck on it, making it seem like it's looking very upset at the two tiny Advil in front of it I placed there for both scale and comedy

A larger than softball sized grapefruit my 13 inexplicably brought home to try, with googly eyes stuck on it, making it seem like it's looking very upset at the two tiny Advil in front of it I placed there for both scale and comedy

Medical science: Ahaha we have invented tens of thousands of life improving and saving medications ahaha we are unstoppable

Grapefruit:

31.08.2025 15:05 👍 627 🔁 198 💬 13 📌 8

*looks across campus*

Yup…still producing plutocrats

31.08.2025 15:32 👍 2 🔁 2 💬 0 📌 0
Post image Post image Post image Post image

Back from two weeks of Summer School in #Cargèse, great venue and discussions!

Bringing back many memories and a whole lot of new ideas to try 🧬

#biomolecules #evolution

30.08.2025 21:42 👍 1 🔁 0 💬 0 📌 0

De novo once meant no BLAST hit but later sensitive methods revealed that many designs had hits. Now TMscore is used, but it’s easy to game by adding helices or rewiring secondary structures due to its scores length normalization. I wish new functions eg. unknown enzymatic reactions would be de-novo

31.07.2025 17:59 👍 9 🔁 1 💬 1 📌 1

Marron
Assainissement et Pluvial.

Violet
Chauffage et climatisation.

Vert
Télécommunications ; Feux tricolores et Signalisation routière TBT.

Blanc
Zone de travaux.

Rose
Zone d’emprise multi-réseaux.

03.07.2025 22:15 👍 24 🔁 1 💬 1 📌 1

Norme NF P 98-332 :

Rouge
Electricité BT, HTA ou HTB, éclairage ; Feux tricolores et Signalisation routière.

Jaune
Gaz combustible (transport ou distribution) et Hydrocarbures.

Orange
Produits chimiques.

Bleu
Eau potable.

03.07.2025 22:15 👍 21 🔁 1 💬 2 📌 0
Post image Post image Post image

For many of those who were asking on BLOW5 vs POD5 for nanopore signal data, here is a finally detailed benchmark we did:
biorxiv.org/content/10.1...
Summary: performance of BLOW5 is >= POD5 (from ~= to 100X, see below), with benefit of having ~3 dependencies instead of >50.

05.07.2025 04:26 👍 14 🔁 9 💬 1 📌 0

I discovered to my great dismay that teabags don't float on milk

04.07.2025 08:45 👍 0 🔁 0 💬 0 📌 0
Portail Emploi CNRS - Offre d'emploi - Doctorant en bioinformatique structurale et évolution des protéines (H/F)

Great news! I’m hiring a PhD student in structural #Bioinformatics to work on modeling protein conformations and interactions at @i2bcparissaclay.bsky.social
as part of the ANR SPPICES project! 🚀

📅 Start: 1 Sept 2025
⏳ Deadline: 23 June 2025
👉Apply now: emploi.cnrs.fr/Offres/Docto...

12.06.2025 09:33 👍 8 🔁 8 💬 1 📌 1

I worry that escalating war with Iran will be used to whip up more fear and hate for non-white immigrants, particularly those of Arab descent, and be used for unjust deportations.

22.06.2025 03:33 👍 17174 🔁 2255 💬 560 📌 170
Preview
Que faire, au lieu de favoriser l’avion au détriment du train ? Les politiques d’achat publiques favorisent l’avion au détriment du trainLes administrations et organismes publics, et les grandes entreprises privées, ont recours à des agences de voyage « professio…

blogs.mediapart.fr/david-monnia...

Que faire, au lieu de favoriser l’avion au détriment du train ?

22.06.2025 09:16 👍 9 🔁 7 💬 1 📌 0

Oggi Parigi è una palla di fuoco

21.06.2025 16:10 👍 0 🔁 0 💬 0 📌 0
Video thumbnail

“Where is it? Where is the warrant?”

Watch NYC comptroller and mayoral candidate Brad Lander detained at an immigration court⬇️

17.06.2025 19:54 👍 8620 🔁 2870 💬 523 📌 210
Post image

Ribaltiamo le cattedre e rompiamo gli schemi!

Dieci giorni di orditure, disfacimenti, esplosioni e rammendature per co-progettare la città di Bari su tre sfide urbane 💬🌱🤝 per migliorare la qualità di vita dell3 cittadin3.

Curiosə? Hai tempo fino al 16 Giugno per iscriverti 🔥

baricittaperta.xyz/it

15.06.2025 08:51 👍 1 🔁 0 💬 0 📌 0
Preview
Novo Nordisk's Canadian Mistake

lol

www.science.org/content/blog...

15.06.2025 06:40 👍 1 🔁 0 💬 0 📌 0
Video thumbnail

“Tasted a little tear gas— tasted like fascism”

08.06.2025 04:40 👍 54294 🔁 15689 💬 693 📌 1031

Internet connection down in #Jussieu campus @sorbonne-universite.fr 😥

03.06.2025 08:22 👍 2 🔁 0 💬 0 📌 0

Non stiamo messi molto meglio che oltreoceano

01.06.2025 10:07 👍 1 🔁 0 💬 1 📌 0

Thank you @joshuasweitz.bsky.social for making this visually effective set of plots that puts into perspective the scale of the announced cuts to NIH, NSF and NASA

31.05.2025 12:49 👍 30 🔁 10 💬 0 📌 0

😥

29.05.2025 15:57 👍 0 🔁 0 💬 0 📌 0

My father worked in a tire factory in Appalachia. Friends and family in the military. Used to vote Republican. Got into college on a diversity program for the underprivileged. Ended up a Harvard professor. And now my funding is terminated because we're trying to stick it to the elites.

28.05.2025 15:07 👍 180 🔁 54 💬 4 📌 3

this is very sad and worrisome

28.05.2025 11:36 👍 0 🔁 0 💬 0 📌 0
Post image

🧬 Great talk (and life lessons) by @ardemp.bskyverified.social at IBPS! Crazy how widespread are the medical conditions where Piezo mechanosensitive proteins are implied.

28.05.2025 08:22 👍 0 🔁 0 💬 0 📌 0
Preview
GitHub - TravisWheelerLab/stk2fasta: Split Stockholm file into FASTA files Split Stockholm file into FASTA files. Contribute to TravisWheelerLab/stk2fasta development by creating an account on GitHub.

Does anybody in #bioinformatics need a #Rust program to convert Stockholm format into FASTA? I'm using this to split multiple sequence alignments in an STK file into separate FASTA files. github.com/TravisWheele...

04.02.2025 21:22 👍 3 🔁 2 💬 0 📌 0
Great work by 
@NSF
 canceling 402 wasteful DEI grants ($233M in savings), including $1M for “Antiracist Teacher Leadership for Statewide Transformation”.  

See the NSF update below.  Grant awards will be based on merit, competition, equal opportunity, and excellence.

Great work by @NSF canceling 402 wasteful DEI grants ($233M in savings), including $1M for “Antiracist Teacher Leadership for Statewide Transformation”. See the NSF update below. Grant awards will be based on merit, competition, equal opportunity, and excellence.

🧪 DOGE is reporting cancelling 402 NSF grants today.

And let's recap: this is for awards that NSF has **ALREADY** judged as aligned with its mission in law, which includes broadening participation in STEM.

It bears repeating: the law supersedes exec orders. For more: www.aaup.org/sites/defaul...

19.04.2025 02:30 👍 93 🔁 59 💬 0 📌 3

today i battled again with unsupported bioinformatic softwares from 2008 and i lost. anyone has ever compiled rasmol succesfully?

14.04.2025 21:03 👍 1 🔁 0 💬 0 📌 0
Post image

1/

"Just do a quick analysis."

If you're a bioinformatician, you've heard this before.

But here's the truth 👇

12.04.2025 16:26 👍 26 🔁 10 💬 1 📌 2

doing both is the way to dig your own grave 🥲

13.04.2025 20:38 👍 1 🔁 0 💬 0 📌 0

io vivo per scendere dalle metro in corsa

07.03.2025 18:42 👍 0 🔁 0 💬 0 📌 0