MS Bioworks

It's the needle that is of most interest to me

I heard we were struggling to power the 58GW data centers but apparently the hour thing fixed that #lostsleep #grumpykids

I don't think it can. I'm just wondering if anyone has tried to find, or make, a replacement for the needle.

It's time for more PI eGPU videos!

Vanquish Neo users, has anyone had a crack at a third party substitute for this needle? #Proteomics #TeamMassSpec

The Radoff-JEC Group Sends Open Letter to Seer, Inc. Unconflicted Independent Directors Meeta Gulyani and Nicolas Roelofs HOUSTON, March 04, 2026--Bradley L. Radoff and Michael Torok (together with certain of their affiliates, the "Radoff-JEC Group"), who collectively own approximately 7.6% of the outstanding common stoc...

Mind blowing! #Proteomics

finance.yahoo.com/news/radoff-...

.... any particular mod you are looking at...?

a man in a suit and tie sitting in a chair ALT: a man in a suit and tie sitting in a chair

221B not available?

The MicrobeAtlas database: Global trends and insights into Earth’s microbial ecosystems MicrobeAtlas (www.microbeatlas.org) is an integrated, reference-based resource for truly planet-wide microbiomics, analyzing hundreds of thousands of microbial lineages across diverse environments, co...

This is an incredible resource:

The MicrobeAtlas Database www.cell.com/cell/fulltex...

Mascot Newsletter logo.

Mascot Newsletter, February 2026:

Strange software errors? Check your disk space.

Proteomic signatures in human fingertip regeneration.

Customise columns in the search log.

www.matrixscience.com/nl/202602/ne...

#proteomics #massspec

Me at the Blavatnik Awards, with my fellow finalists and giving me lecture

It was a wonderful experience to receive my Blavatnik Awards in the UK Finalist medal in the gorgeous Banqueting House this week!

Then give a public lecture at the Royal Society of Medicine!

A giant thank you to the Blavatnik Family Foundation and the The New York Academy of Sciences

Michael Booth, PhD, 2026 Blavatnik Awards in the UK Finalist in Chemical Sciences YouTube video by The New York Academy of Sciences

Here you can watch this excellent video the Blavatnik Awards made of me explaining our research into nucleic acids 🧬❤️! 🧪 #chemsky
youtu.be/KMFJs-oF-do?...

US military leaders pressure Anthropic to bend Claude safeguards Anthropic presents itself as most safety-forward AI firm and Pentagon has threatened penalties if it does not yield

www.theguardian.com/us-news/2026...

Second half! Let's go. Glory awaits!

A universal monoallelic human leukocyte antigen class II immunopeptidomic platform for defining the immunogenicity potential of therapeutic proteins - Communications Biology Monoallelic HLA-DRB1 cell line panel with universal BCR unlocks the immunopeptidomic potential of B cells.

This MAPPS paper from 2025 is incredible. It's got pharma flex vibes that are frankly admirable.

www.nature.com/articles/s42...

How DeepSeek supercharged AI's distillation problem Silicon Valley is reckoning with an AI development technique that could upend the leaderboard. Distillation is the idea that a small team can make an advanced AI model by extracting knowledge from a l...

Interesting video about distillation from @cnbc.com

www.cnbc.com/video/2025/0...

Why You Can’t Remember Being a Toddler This form of amnesia is almost universal, but has long been overlooked.

To get a better sense of precisely when #memories are formed and forgotten, Sarah Power @mpib-berlin.bsky.social built a media room where she observed 400 toddlers: "We've been very surprised at their ability to encode and retain these episodic-like memories." time.com/7380496/why-... @time.com

One of the more useful out the box #AI tools at the moment: asta.allen.ai

Fantastic for summarizing articles.

Detecting and preventing distillation attacks Anthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems.

This article from Anthropic really takes the shines off the free DeepSeek models

www.anthropic.com/news/detecti...

Humbled our work has prompted a News and Views article in Nature Chemistry by Omer Harel and @jbaram.bsky.social

www.nature.com/articles/s41...

GitHub - rdkit/rdkit: The official sources for the RDKit library The official sources for the RDKit library. Contribute to rdkit/rdkit development by creating an account on GitHub.

ChatGPT recommends this: github.com/rdkit/rdkit

Right. So, find an open API for something like Chemdraw. Make an MCP server for it and then call that. And do it all locally with Chinese models and won't cost you a dime. And it will work and not be trash.

a man with a beard is screaming with his mouth open in a sepia toned photo . ALT: a man with a beard is screaming with his mouth open in a sepia toned photo .

Here you go, the reds better!

Did it get the SMILES right?

Good new histone publication from @jyates.bsky.social and colleagues

#FragPipe #Proteomics

www.biorxiv.org/content/10.6...

Rapid Antibody Structural Characterization and Quantification via Microdroplet Trypsin Digestion | Journal of the American Society for Mass Spectrometry pubs.acs.org/doi/10.1021/...

Obama gets his first touch of the All-Star game

A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller?

Excited to share our latest work in @science.org on a new small polymerase.
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