MeunierLab

Had not seen this king parrot for months and he just called me out 😍

Jacaranda time at UQ! Best time of the year😍

Nanoscale spatiotemporal cluster analysis of expressed and endogenous proteins Nature Protocols - This is a Protocol for fluorescent intrabody localization microscopy imaging, which enables single-particle tracking of proteins in living cells, using unique nanobodies to...

rdcu.be/eDiyh

Nonmuscle myosin II regulates presynaptic actin and neuronal mechanobiology in Drosophila Neurons and muscles must maintain structural contact despite mechanical strain. Ermanoska et al. identify a presynaptic actomyosin core at Drosophila neuro

Nonmuscle myosin II regulates presynaptic actin and neuronal mechanobiology in Drosophila url: rupress.org/jcb/article-...

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency Republicans on spending committee push back against proposed reorganization and overhead cuts

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency | Science | AAAS www.science.org/content/arti...

A massive thank you to the EMBO team for allowing us to publish this story and making the cover. Fat-tagging (myristoylation) at the synapse is critical for synaptic plasticity:) Congrats to all involved n the @meunierlab.bsky.social

Many thanks Andrew. Sorry I just saw this now!

The surprising role of fat in memory formation An exciting new avenue

stories.uq.edu.au/the-surprisi...

Lysine myristoylation mediates long-term potentiation via membrane enrichment of synaptic plasticity effectors | The EMBO Journal imageimageSynaptic long-term potentiation (LTP) involves generation of myristic acid from synaptic membrane phospholipids via the activity of the phospholipase A1 DDHD2. This work shows that myristic ...

5 years in the making! Myristoylation is necessary for LTP and memory acquisition. Great PhD work from Ben Matthews: The EMBO Journal www.embopress.org/doi/full/10....

It looks like Musk will be trying to use x for training his AI. You might remove stuff from there…

Nanobinders for Synaptotagmin 1 enable the analysis of synaptic vesicle dynamics in rodent and human models. Synaptic neurotransmission is a critical hallmark of brain activity and one of the first processes to be affected in neural diseases. Monitoring this process, and in particular synaptic vesicle recycl...

Excited for our latest work! We developed nanobinders for the luminal domain of Synaptotagmin 1 (calcium sensor for synaptic vesicles). Thanks among others to @verstrekenlab.bsky.social @opazo.bsky.social @meunierlab.bsky.social @volkerhaucke-lab.bsky.social www.biorxiv.org/content/10.1...

Great to host Laurent Groc and KB Sibarita at Qbi. A single-molecule festival

Today's lectures were given by @meunierlab.bsky.social and Victor Anggono on probing synaptic with super resolution microscopy, and the molecular structure of learning and memory. In the afternoon the students will have a go at super resolution, and TIRF microscopy.

Much needed holidays in Tuscany. Long haul back to Brisbane starts tomorrow 😳

Beautiful Normandie! Thanks to Maité Montero for her kind invitation to visit her lab in Rouen!

On the road again… where am I?

🚨 We're hiring! 🚨 Brandeis University is seeking a tenure-track Assistant Professor in Bioengineering, with a focus on synthetic biology or biomolecular engineering. Please DM me with any questions! academicjobsonline.org/ajo/jobs/28825 (1/2)

So true…

Nice start of the weekend🤩

Like ‘old Twitter’: The scientific community finds a new home on Bluesky After recent changes to Elon Musk’s X, a gradual migration turns into a stampede

The sky is the limit again!
www.science.org/content/arti...

Beautiful! You should ask @robparton.bsky.social

I wish…

I am a neuroscientist trying very hard to understand how the chaos in our cells makes sense.

@fredsteyn.bsky.social I am your first follower😊

Very cool

Sure I am not quite sure how. I thought people could self add themselves. Anyhow you are very welcome

go.bsky.app/TAyxRFP

Still amazed by the effect of hericene A on neurite outgrowth in vitro, on BDNF and pTrkB levels in vivo and enhanced cognition in two independent memory paradigms. There is something there! Check this out onlinelibrary.wiley.com/doi/full/10....
#neuron, #microscopy, #axon, #neurotrophins

LRP4 controls SO MUCH more! And it all seems to do so from the PRESYNAPSE (answering that HUGE open question). LRP4 controls synapse growth, cytoskeletal organization, postsynaptic protein recruitment, AND maturation. Multiple processes for the price of one cell surface protein!