Mike Coston

CDC Preprint: A Newly Emergent N1 Neuraminidase Associated with Clade 2.3.4.4b HPAI A(H5) Viruses in North America #19,082 In the fall of 2024 - barely six months after the discovery of the ` Bovine' B3.13 genotype of H5N1 circulating in U.S. dairy catt...

AFD Blog `CDC Preprint: A Newly Emergent N1 Neuraminidase Associated with Clade 2.3.4.4b HPAI A(H5) Viruses in North America' #H5N1 afludiary.blogspot.com/2026/03/cdc-...

Asymptomatic, acute and persistent COVID-19 symptom changes over the course of three infections Most acute and persistent COVID-19 symptoms decrease and asymptomatic infections increase over time, after multiple infections and with vaccination, but plenty remain.

Asymptomatic, acute and persistent COVID-19 symptom changes over the course of three infections virologydownunder.com/asymptomatic...

Viruses: Novel Reassortant H5N2 Highly Pathogenic Avian Influenza Viruses from Backyard Poultry in Mexico #19,081 Influenza A's superpower is its ability simultaneously infect a host with 2 or more strains, swap genetic material, and generate a...

AFD Blog `Viruses: Novel Reassortant H5N2 Highly Pathogenic Avian Influenza Viruses from Backyard Poultry in Mexico' #H5N2 #H5N1 afludiary.blogspot.com/2026/03/viru...

Cell: Dynamics of Natural Selection Preceding Human Viral Epidemics and Pandemics #19,080 We've a fascinating, albeit somewhat controversial, study published last week in Cell which questions whether whether animal   viru...

AFD Blog `Cell: Dynamics of Natural Selection Preceding Human Viral Epidemics and Pandemics ' afludiary.blogspot.com/2026/03/cell...

South Korea: MAFRA Investigation Into Biosecurity Lapses on HPAI Affected Poultry Farms #19,079 Despite more than 2 decades of dealing with extensive bird flu outbreaks, and numerous warnings to farmers (see here , here , her...

AFD Blog `South Korea: MAFRA Investigation Into Biosecurity Lapses on HPAI Affected Poultry Farms' #H5N1 #H5N9 afludiary.blogspot.com/2026/03/sout...

Nature Comms: Mapping Global Avian Influenza Risk Patterns Through Waterbird Activity Entropy #19,078 During the latter half of the 20th century Asia - and China in particular - had earned the reputation of being the `cradle of in...

AFD Blog `Nature Comms: Mapping Global Avian Influenza Risk Patterns Through Waterbird Activity Entropy' #H5N1 afludiary.blogspot.com/2026/03/natu...

California DPH Advice to Public After H5N1 Detected in Elephant Seals Credit Wikipedia #19,077  Ten days ago in  California: Background on the Outbreak of H5N1 in Elephant Seals at Año Nuevo Natural Reserve , w...

AFD Blog `California DPH Advice to Public After #H5N1 Detected in Elephant Seals' afludiary.blogspot.com/2026/03/cali...

IJID: Lack of Respiratory Droplet Transmission of Two Recent Human Influenza A(H5N1) Viruses in Female Ferrets #19,076 Today we've a study that reminds us how much we've yet to learn about what it takes for a novel zoonotic virus - like HPAI H5Nx - ...

AFD Blog `IJID: Lack of Respiratory Droplet Transmission of Two Recent Human Influenza A(H5N1) Viruses in Female Ferrets' #H5N1 afludiary.blogspot.com/2026/03/ijid...

Asymptomatic, acute and persistent COVID-19 symptom changes over the course of three infections Data from a UK healthcare worker cohort published in 2024 examined how signs and symptoms of COVID-19 changed after 1, 2, or 3 SARS-CoV-2 lab-confirmed infections. Those with no symptoms through to those whose symptoms persisted for >12 weeks recalled their experience, and the cohort included vaccinated and unvaccinated people and spanned the presence of different virus variants. Humans not modelling The SARS-CoV-2 Immunity and Reinfection EvaluatioN (SIREN) study is a large cohort study of UK healthcare workers. The participants were tested each fortnight by SARS-CoV-2 PCR and regular antibody testing (serology).

Most acute and persistent COVID-19 symptoms decrease and asymptomatic infections increase over time, after multiple infections and with vaccination, but plenty remain.

UK Defra Announces New Avian Influenza Vaccine Trials Begin in UK #19,075 With agricultural losses mounting from avian influenza, more and more farmers are clamoring for the ability to protect their flock...

AFD Blog `UK Defra Announces New Avian Influenza Vaccine Trials Begin in UK' #H5N1 afludiary.blogspot.com/2026/03/uk-d...

OFFLU: Global Overview of Spread & Impact of H5 Clade 2.3.4.4b HPAI virus in Wildlife, 2020-2024 #19,074 Offlu has just published a 77-page overview on the impact of the  HPAI H5Nx virus on global wildlife during the opening years (2020...

AFD Blog `OFFLU: Global Overview of Spread & Impact of H5 Clade 2.3.4.4b HPAI virus in Wildlife, 2020-2024' #H5N1 #H5Nx afludiary.blogspot.com/2026/03/offl...

Vaccines: Investigation of Potential Cross-Protection Conferred by the Seasonal Influenza Vaccine Against Swine Influenza A Viruses of Pandemic Potential #19,073 Last week Spain reported a rare human infection with H1N1v swine influenza in a patient in Catalonia with no known history of ex...

AFD Blog `Vaccines: Investigation of Potential Cross-Protection Conferred by the Seasonal Influenza Vaccine Against #Swine #Influenza A Viruses of Pandemic Potential' afludiary.blogspot.com/2026/03/vacc...

J.I.D.: Development & Characterization of Candidate Vaccine Viruses against HPAI A(H5) Viruses for Rapid Pandemic Response WHO H5 CVV list (n=46) #19,072 Two days ago, in WHO: Candidate Vaccine Viruses for Pandemic Preparedness - Feb 2026 , we looked at the lat...

AFD Blog `J.I.D.: Development & Characterization of Candidate Vaccine Viruses against HPAI A(H5) Viruses for Rapid Pandemic Response' #H5N1 afludiary.blogspot.com/2026/03/jid-...

Nature Comms: The Risk of Kidney Disease Increases Following SARS-CoV-2 Infection Compared to influenza Nature Med. Review: Extrapulmonary manifestations of COVID-19 #19,071 Now that 90% of the world's nations are no longer reporting COVID in...

AFD Blog `Nature Comms: The Risk of Kidney Disease Increases Following SARS-CoV-2 Infection Compared to influenza' #COVID afludiary.blogspot.com/2026/03/natu...

WHO: Candidate Vaccine Viruses for Pandemic Preparedness - Feb 2026 Credit NIAID #19,070 In addition to deciding which influenza viruses to include in the next seasonal flu vaccine (see  WHO Recommendations f...

AFD Blog `WHO: Candidate Vaccine Viruses for Pandemic Preparedness - Feb 2026' afludiary.blogspot.com/2026/03/who-...

FluView Week 7: Influenza Remains Elevated & Additional Reports of Antiviral Resistance https://www.cdc.gov/fluview/surveillance/2026-week-07.htm l #19,069 Three months into this year's influenza season and flu activity remain...

AFD Blog `FluView Week 7: Influenza Remains Elevated & Additional Reports of Antiviral Resistance' #H1N1 afludiary.blogspot.com/2026/02/fluv...

WHO Recommendations for Influenza Vaccine Composition for the 2026-2027 Northern Hemisphere Influenza Season Credit ACIP   #19,068 Twice each year international influenza experts meet to discuss recent developments in human and animal influenza viru...

AFD Blog `WHO Recommendations for Influenza Vaccine Composition for the 2026-2027 Northern Hemisphere Influenza Season' #H3N2 #H1N1 afludiary.blogspot.com/2026/02/who-...

South Korea: MAFRA Extends Special Quarantine Period for 3rd Month (to March 31st) #19,067 On January 5th, South Korea ordered  Special Quarantine Measures Implemented for one Month to Prevent the Spread of HPAI ,  which ...

AFD Blog `South Korea: MAFRA Extends Special Quarantine Period for 3rd Month (to March 31st)' #H5Nx #ASF #FMD afludiary.blogspot.com/2026/02/sout...

California: Background on the Outbreak of H5N1 in Elephant Seals at Año Nuevo Natural Reserve California Parks #19,066 Yesterday, California Parks and UC Santa Cruz announced the first U.S. detection of H5N1 in Elephant Seals at t...

AFD Blog `California: Background on the Outbreak of #H5N1 in Elephant Seals at Año Nuevo Natural Reserve' afludiary.blogspot.com/2026/02/cali...

South Korea: H5N9 Rising #19,065 Last last year, South Korea's MAFRA Reported  Increased Infectivity & Pathogenicity of This Year's Avian Flu Strains , which - for...

AFD Blog `South Korea: #H5N9 Rising' afludiary.blogspot.com/2026/02/sout...

Nature Comms: Baloxavir outperforms oseltamivir, favipiravir, and amantadine in treating lethal influenza A(H5N1) HA clade 2.3.4.4b infection in mice CDC Influenza Antiviral Medications:  Summary for Clinicians - Jan 2026 #19,062 During any novel influenza pandemic - even one as long ant...

Which drug should countries be stockpiling in case of an #H5N1 pandemic? Maybe #baloxavir? afludiary.blogspot.com/2026/02/natu... #birdflu

Preprint: Near Real-time Data on the Human Neutralizing Antibody Landscape to Influenza Virus as of Early 2026 to Inform Vaccine-strain Selection Credit NIAID #19,064 Later this week the WHO is expected to convene their semi-annual vaccine selection committee to consider the makeup of ...

AFD Blog `Preprint: Near Real-time Data on the Human Neutralizing Antibody Landscape to Influenza Virus as of Early 2026 to Inform Vaccine-strain Selection' #H3N2 #H1N1 afludiary.blogspot.com/2026/02/prep...

Preprint: Hematogenous Neuroinvasion and Genotype-dependent Transmission of Influenza A H5N1 Viruses in the Cat Host Based on USDA Data #19,063 Based on limited - and admittedly opportunistic - surveillance, felines ( domestic cats, mountain lions, bobcat...

AFD Blog `Preprint: Hematogenous Neuroinvasion and Genotype-dependent Transmission of Influenza A #H5N1 Viruses in the #Cat Host' afludiary.blogspot.com/2026/02/prep...

Nature Comms: Baloxavir outperforms oseltamivir, favipiravir, and amantadine in treating lethal influenza A(H5N1) HA clade 2.3.4.4b infection in mice CDC Influenza Antiviral Medications:  Summary for Clinicians - Jan 2026 #19,062 During any novel influenza pandemic - even one as long ant...

AFD Blog `Nature Comms: Baloxavir outperforms oseltamivir, favipiravir, and amantadine in treating lethal influenza A(H5N1) HA clade 2.3.4.4b infection in mice' #H5N1 afludiary.blogspot.com/2026/02/natu...

South Korea: MAFRA Detects ASF DNA in Pig Feed Additive as Outbreaks Increase (n=18) #19,061 Just over a month ago (Jan 16th) South Korea reported their first African Swine Fever outbreak of 2026 , and since then 17 more ...

AFD Blog `South Korea: MAFRA Detects #ASF DNA in Pig Feed Additive as Outbreaks Increase (n=18)' afludiary.blogspot.com/2026/02/sout...

J. Inf.: Zoonotic Threat of Novel H6N2 Avian Influenza Virus with Internal Genes Exclusively Derived from H9N2, China, 2025 Transmission patterns between different hosts of  H6 viruses.   Credit: JOI: Prevalence and Transmission of Influenza A (H6) Viruses #19,06...

AFD Blog `J. Inf.: Zoonotic Threat of Novel #H6N2 Avian Influenza Virus with Internal Genes Exclusively Derived from #H9N2, China, 2025' afludiary.blogspot.com/2026/02/j-in...

New Jersey's Wild Bird Die-Off #19,059 The Northern Hemisphere is at - or near - peak avian flu for this winter season, with literally scores of outbreaks being reporte...

AFD Blog `New Jersey's Wild Bird Die-Off' #H5N1 afludiary.blogspot.com/2026/02/new-... h/t @FluTrackers

When You're in the Market For Bird Flu Based on USDA Data - Graph created with Gemini #19,058 Since the arrival of H5N1 in late 2021, the  USDA has reported  64 outbreaks  in li...

AFD Blog `When You're in the Market For Bird Flu' #H5N1 afludiary.blogspot.com/2026/02/when...

EID Journal: Vaccine-Like African Swine Fever Virus Strain in Domestic Pigs, Thailand, 2024 How ASF Spreads #19,057 We've a bit of a medical mystery today courtesy of an early release research article published this week in the EI...

AFD Blog `EID Journal: Vaccine-Like African Swine Fever Virus Strain in Domestic Pigs, Thailand, 2024' #ASF afludiary.blogspot.com/2026/02/eid-...

Pathogens: Clinical and Laboratory Findings in Cats with Confirmed Avian Influenza A/H5N1 Virus Infection During the 2023 Outbreak in Poland #19,056 Three summers ago, when domestic feline infection with HPAI H5N1 was still considered a fairly rare event, we followed an unusually ...

AFD Blog `Pathogens: Clinical and Laboratory Findings in #Cats with Confirmed Avian Influenza A/H5N1 Virus Infection During the 2023 Outbreak in Poland' #H5N1 afludiary.blogspot.com/2026/02/path...