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Jianhan Chen

@umassmdlab

Professor at UMass Amherst; computational biophysics: intrinsically disordered proteins, ion channels, protein nanopores, biomolecular condensates, multi-scale RNA and protein modeling, enhanced sampling

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An Intermediate Resolution Model of RNA Dynamics and Phase Separation with Explicit Mg2+ RNAs are major drivers of phase separation in the formation of biomolecular condensates. Recent studies suggest that RNAs can also undergo protein-free phase separation in the presence of divalent ion...

Excited to share our new coarse grained model of dynamic RNA for phase separation simulations. The model is still evolving and any feedback is welcomed!

www.biorxiv.org/content/10.1...

03.12.2024 03:13 ๐Ÿ‘ 4 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0