This is beautiful. I’m curious, if you take Brian hie and Peter kim’s approach with llms to “improve” your small protein domains, do you think you’ll see a systematic trend to more or less dynamics?
This is beautiful. I’m curious, if you take Brian hie and Peter kim’s approach with llms to “improve” your small protein domains, do you think you’ll see a systematic trend to more or less dynamics?
Suggestions for a chemically titratable promoter in human cell culture? Titration of dox with TetOn gives a bimodal response (largely changes on:off ratio). I miss my beautifully tunable yeast system from Azizoglu, Brent and Rudolf (elifesciences.org/articles/69549) #synbio #RNA
Amazing, well done.