Cancer and Immune Signalling Lab (CISL)

Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancer - PubMed Pancreatic ductal adenocarcinoma (PDAC) is driven by genetic alterations in the pancreatic epithelium (e.g., KRAS) coupled with dysregulated innate immunity that triggers tumor-promoting chronic inflammation. However, the identity of innate immune molecular regulators as therapeutic targets in PDAC …

Very pleased to share our latest published work on the role of the innate immune inflammasome adaptor ASC in promoting pancreatic cancer. Thanks to all in our multinational team!
pubmed.ncbi.nlm.nih.gov/41654528/
@saigenci.bsky.social
@natcomms.nature.com

Very honoured to be the first Australian recipient of the prestigious Japanese Cancer Association (JCA) International Award, presented at the annual JCA2025 conference in Kanazawa. Special thanks to my JCA colleagues, especially JCA President, Prof Masanobu Oshima.
@saigenci.bsky.social

Learn more about South Australia's new university for the future.

We're hiring! Looking for talented Post-doctoral researchers in our program at SAiGENCI (Adelaide University) to study the role of the immune system in cancer. See below for details.....
careers.adelaide.edu.au/cw/en/job/51...

Fellows advance immunotherapy and tumour inflammation research

Very grateful to the Ainsworth Foundation for their generous support and investment in our Tumour Inflammation and Immunotherapy Program at SAiGENCI.
www.adelaide.edu.au/newsroom/new...

Fellows advance immunotherapy and tumour inflammation research

Very grateful to the Ainsworth Foundation for their generous support and investment in our Tumour Inflammation and Immunotherapy Program at SAiGENCI.
www.adelaide.edu.au/newsroom/new...

Very well done, and congratulations!

SAiGENCI Annual Public Lecture 2025 YouTube video by Health & Medical Sciences - University of Adelaide

Wonderful to see so many people attend the Annual SAiGENCI Public Lecture last night to hear our research on the innate immune system, inflammation and immunotherapy in cancer. Fantastic talk also from my co-speaker Dr Mara Zeissig. Thank you to everyone.
www.youtube.com/watch?v=z2Kc...

<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library Positive research cultures provide the environment for scientists to explore ideas, grow as individuals, develop team science and create a positive impact on those around them. Here we focus on key a...

Academics get so jaded about institutions, when they reach a #leadership position many feel #researchculture is unactionable. Me and @deefitzgerald.bsky.social wrote a guide in @immunolcellbiol.bsky.social on leadership nurturing a positive culture 1/13

onlinelibrary.wiley.com/doi/10.1111/...

x.com/Mohamed_I_Sa...
Proud to be a part of this NHMRC Ideas Grant ($1M) team to investigate the role of proteases in lung cancer.
@University of Adelaide
@SAiGENCI

Big congratulations to Brendan Jenkins who has been selected as the recipient of the ICIS 2023 Distinguished Service Award! @Lab_Jenkins @ciiid_Hudson @Hudson_research @Monashuni @SAiGENCI @UniofAdelaide...

Research Group Leaders in “Tumour Inflammation and Immunotherapy Program” at SAiGENCI...

📢💻🧪 2 #PhD #Scholarships available @SAiGENCI:

1) Hybrid wet-dry: #multiomics to predict neoadjuvant response in #cancer

2) #Bioinformatics, comp-bio: large-scale #singlecell modelling and infrastructure

🔗https://researchers.adelaide.edu.au/profile/stefano.mangiola#my-research

Please share! 🙏