Such a disheartening finding... wapo.st/4d4DgLi
06.03.2026 21:36
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Backtracking on its advice has unfortunately become common at FDA. It's one thing to miss the mark, and altogether different if the mark keeps moving. wapo.st/4b0NGsW
Table showing patient willingness to enroll in clinical trials with/without conditionally approved drugs (N=1597). It lists willingness levels from 1(Not likely) to 7(Very likely), showing patient numbers and percentages for both scenarios.
Among cancer survivors surveyed, the presence of a conditionally approved drug reduced willingness to enroll in clinical trials, and many attributed higher levels of testing and efficacy to such drugs than warranted.
ja.ma/4qUd3m0
Trump’s envoy Jeff Landry said of Greenland that “small settlements are without permanent doctors, diagnostic tools, or specialist care — forcing residents to travel great distances for vital treatments that should be available at home.” That describes much of the U.S. Where is our hospital ship?
Spending millions of dollars to send a hospital ship to another country to serve a population of 57,000 people while simultaneously passing policies that kick 15 million plus Americans off of insurance. apnews.com/article/fact...
Unpredictability of late has come from the top down.2/2 www.iqvia.com/locations/un...
Sen. Cassidy report on reforming FDA written for a different FDA than we have now. He writes "...disconnect between the forward-leaning rhetoric and thought leadership of senior FDA officials and cautious reviewer practice creates further unpredictability." 1/2 www.help.senate.gov/imo/media/do...
Financial burdens keep too many people out of cancer clinical trials. 25 orgs ask the Trump administration for actions to ease those burdens. www.fightcancer.org/releases/rur...
A very big deal!
Some mornings I wonder if it wouldn't be easier to organize and launch a polar scientific expedition than get my kids up and off to school.
The normal operation of the government and issuance of research grants is a layered interdependent process, such that there are many places for it to grind to a halt, whether caused intentionally or not.
Join the #MRCTCenter and #EACTProject on December 9 at 10 AM ET for “Mitigating Financial Toxicity for Participants in Clinical Trials,” a webinar on the financial burdens of trial participation and strategies to reduce hardship. Link to the registration: lp.constantcontactpages.com/ev/reg/x4bhu...
Are you part of a STEM group seeking to take your public engagement to the next level? Research America offering $4k microgrants. Deadline Dec 1. www.researchamerica.org/civic-scienc...
We'll only know true impact in a couple of years when we see if these trials were ultimately completed and published. Broader takeaway, however, still stands that trials as well as research broadly (both ongoing and future) have been greatly impacted by this administration's funding cuts 5/5
No way to know whether data analysis would continue as planned without parent grant. Would like to see additional analysis to understand if trials changed status to terminated after grant cancellation or if they continued anyway.4/5
Reminder that it is wonderful if participants receive benefit from research, but underlying premise of research is that benefit accrues to future patients based on learning, thus potential harm is lost opportunity to gain knowledge as well as ethics of not learning from those who volunteered. 3/5
Article states "...more than 74 000 trial participants were affected." but should have said "Terminated grants funded trials in which 74,000 people had taken part." Depending on indiv circumstances-e.g. whether still getting treatment-patients might have not felt any individual impact. 2/5
Eye-catching headlines from recent JAMA paper exploring effects of funding cuts on trials. I'd argue some problems with characterization of data and how reported in press. No question, the cuts had big impacts, but need to characterize those impacts accurately. 1/5 jamanetwork.com/journals/jam...
Short-term plans are not traditional insurance. People buy insurance to protect them from unmanageable medical bills and short-term plans don't do that, which is why @acscan.bsky.social opposes them. www.washingtonpost.com/health/2025/...
End of an era, but cash in general is quickly falling out of use.
Consequential change to see Dr. Pazdur take reigns at CDER after initially turning it down. He's enormously qualified and a more traditional pick for this post, but in this administration not expected. Will he inject stability and predictability? www.washingtonpost.com/health/2025/...
The thing about science is that sometimes you get it wrong the first time, but the scientific process is unending, so there is still time to get it right. The fact that our understanding of science isn't perfect is not reason to abandon it. www.nytimes.com/2025/10/20/w...
I love the fact that a Nobel prizewinner was the last to learn of his award because he was hiking...https://www.nytimes.com/2025/10/07/health/nobel-prize-medicine-fred-ramsdell.html
It is not enough for a trial to exists somewhere in the U.S., it also needs to be close enough for patients to access, and for many Americans there is little easy access to research participation.
Unprecedented that six former surgeon generals appointed by presidents of both parties unite to denounce RFK Jr. and call out the danger he poses to public health. www.washingtonpost.com/opinions/202...
The NCI "bypass" budget is an unfiltered view of what could really move the needle in cancer research. The latest requests more money to get trial infrastructure into communities and rural areas, and seeks to offset lost grants due to forward-funding policies. www.cancer.gov/research/lea...
The solution? Spread NCI funding out to more community and rural site to boost infrastructure to conduct research. Read our blog summary of the paper here: www.cambridge.org/core/blog/20...
Giving everyone in the US with cancer a chance to take part in research can be made difficult by distance. We analyzed who does and doesn't have access to NCI funded sites and found nearly 38% would have to drive over 50 miles, and almost 17% over 100 miles. resolve.cambridge.org/core/journal...
I would have never guessed that NIH would get the money spent, but apparently they will. While a small victory, remember this was done by forward funding lots of grants meaning fewer grants and less research being done. To some degree this is a short-term accounting trick.
Thrilled to see the House Energy and Commerce Committee unanimously advance the #GiveKidsAChanceAct. Thank you for your leadership on behalf of children with cancer. We urge the full House to pass this bill without delay. #ChildhoodCancerAwarenessMonth www.fightcancer.org/policy-resou...