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05.03.2026 13:13
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Congratulations, @animrprfct.bsky.social! Best of luck and looking forward to watching you present in the finals for 3MT! @cmuscience.bsky.social
How does treatment induced antibiotic resistance happen in real-world infections? We analysed 25k Pseudomonas isolates from 180 patients in a clinical trial to find out! TLDR: The ecological and evolutionary paths are surprisingly diverse & complex even in patients receiving identical treatment…
#microsky
Starvation-independent alarmone production inhibits translation through GTP depletion
- bioRxiv from @heatherfeaga.bsky.social
#ppGpp #Bsubtilis
We call it Greenfield to confuse the Vikings. #pittsburgh
Congrats to Erin and Betsy for passing their qualifying exams last week!!!! Officially 3 PhD candidates in the lab @cmuscience.bsky.social now! 😎
Summer REU in biofilms! Pls share.
www.binghamton.edu/centers/biof...
Congrats to Sean, Will, and co-authors! Shoutout to @cmuscience.bsky.social Quantitative Biology & Bioinformatics (QBB) MS student Isabelle D'Amico from my lab for her creative work on this cool collaboration!
other key papers that inspired the TA’s lecture:
Peter Jorth’s study on biogeography within lungs during CF infection:
www.cell.com/cell-host-mi...
Joe Harrison, Boo Shan Tseng, et al‘s perspective on Eisha Mhatre & Vaughn Cooper’s biofilm evolution paper:
pubmed.ncbi.nlm.nih.gov/33187833/
Yep, you got it. We talked about how nutrients in the airways vary, impacting microbes. & how the physical structure of the whole respiratory tract supports microbial populations becoming isolated during chronic infection, leading to adaptive radiation like Darwin’s finches in the Galapagos.
In the same theme, TAs Betsy and Erin (PhD students in my lab) presented on thinking of migration of bacteria between upper & lower respiratory tract through the lens of island biogeography. Heavily inspired by this awesome paper & others pubmed.ncbi.nlm.nih.gov/24702670/
Our last two guest lectures in Ecology @cmuscience.bsky.social were part of our theme thinking of infection as an ecologist (human = environment). First, Dr. Yasmin Hilliam (Bomberger Lab at Dartmouth) discussed how respiratory viral infection changes nutrients in airways, impacting microbiomes.
Our latest guest lecture in CMU Ecology class was Dr. Gus Ramirez (CalState LA @zombiephylotype.bsky.social) discussing research cruises, ocean biogeochemistry, & microbe-octopi interactions at sea mounts. Stunning & mind boggling to hear how you sample this stuff that is 1000s of meters underwater.
What is the most profitable industry in the world, this side of the law? Not oil, not IT, not pharma.
It's *scientific publishing*.
We call this the Drain of Scientific Publishing.
Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...
Thread @markhanson.fediscience.org.ap.brid.gy 👇
The evolutionary and ecological consequences of cooperation
-in American Naturalist by @stuwest.bsky.social, @annadewar.bsky.social, @ryosukeiritani.bsky.social, Laurence Belcher, and @asgriffin.bsky.social
www.journals.uchicago.edu/doi/abs/10.1...
Isn't nature beautiful? 😅
Today’s guest speaker in Ecology @cmuscience.bsky.social was perfect for Halloween: Arkadiy Garber @ironark.bsky.social from the McCutcheon Lab at ASU, discussing bacterial endosymbionts that support the junk food diets of sap-feeding insects! 😈
Microbiologist Paula Welander studies fossils, but not dinosaur bones or ammonite imprints. Instead, she looks for microscopic clues left behind by microbes that lived millions of years ago.
My department at UTK is hiring! 🧪🧫 We are hiring two Assistant Professors, one in Microbial Drivers of Chronic Disease and one in Quantitative Microbe-Plant-Environment Interactions! Come join our growing department of microbiologists. Knoxville is a great place to live!
We had our first guest lecturer in my Ecology class @cmuscience.bsky.social today! Dr. Delaney Miller from the Handelsman lab at Wisconsin Institute for Discovery (@widofficial.bsky.social) & HHMI gave an absolutely beautiful talk on how microbes in the rhizosphere impact plant development.
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
How complex functions, with important physiological and evolutionary impacts get repeatedly and efficiently transferred across genomes?
That’s what we explored using one of the fastest-evolving loci in Bacteria: the capsule locus.
The paper: www.biorxiv.org/content/10.1...
Thread👇
AlphaFold model of the complex formed between HK2 and the SOX10 5′UTR (189–204 nts). The predicted RNA structure is shown in cyan, and HK2 protein is shown in green. HK2 residues and SOX10 mRNA nucleotides at the interaction interface are highlighted in red. Inset: schematic representation of the secondary structure of the SOX10 5′UTR (189–204 nts) predicted by Mfold, with the putative HK2-binding region (194–198 nts) marked in red.
Hexokinase 2 (HK2) is known for its metabolic role in #glycolysis. This study shows that it also functions as an #RNAbindingProtein that regulates mRNA translation, particularly of SOX10, promoting #melanoma cell proliferation independently of glycolysis @plosbiology.org 🧪 plos.io/3ViI1qL
Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation
Penicillium solitum over 8 years in a cheese cave => green-to-white shift
@currentbiology.bsky.social from @benwolfe.bsky.social with @kellerlab.bsky.social
www.cell.com/current-biol...
Neuroscientist Alison Barth @cmu.edu on the science behind Severance & work/life separation 🤓 www.cmu.edu/mcs/news-eve...
Happy to finally see this out! Bassam El Halfi (@bassamhafi.bsky.social - my first rotation student when I started my post-doc in @geiselbiofilm.bsky.social) did an amazing job investigating mechanisms of interspecies metabolic interactions. Check it out! #microsky
journals.asm.org/doi/10.1128/...
Awesome faculty position alert! Tenure-track assistant professor position in Evolutionary Biology, with a focus on organismal responses to environmental change.
Please help spread the word!
apply.interfolio.com/173889
On our way to the Parsek/Woz retreat in Leavenworth, WA!
Here is a demonstration of ice nucleation protein made by Pseudomonas syringe in my #Bio350 #Micronauts in my #Microbiology course at @univpugetsound @ASMicrobiology
