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Anita D'Souza

@dradsouza

Professor | physician-scientist | #mmsm #amyloidosis #immunotherapy #bmt/car-t | quality of life | health services research | hematology

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Latest posts by Anita D'Souza @dradsouza

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This #BlackHistoryMonth, ASH honors the Black pioneers in #hematology whose discoveries, leadership, and advocacy have shaped the field and continue to save lives. Their impact lives on in every breakthrough and every patient served.

18.02.2026 01:58 πŸ‘ 8 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

Looking forward to #ISA2026 in beautiful Montevideo in Nov 2026. Program now available www.isaamyloidosis.org/isa-2026-sym...
Abstract submission window: 3/2026-7/1/26.

04.02.2026 12:47 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

political appointees at NIH and why

Batt: the key thing is to not be political

She: dumbass you have 5x the political appointees big used to have

03.02.2026 16:48 πŸ‘ 10 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

Sen Baldwin now, asking about multi year funding. How is this not a huge setback for research? How many fewer grants were funded?
Batt: begins a stemwinder
Baldwin cuts him off and gives him the number, then talks about the labor HHS bill that limits MY

Baldwin now talking about huge increase in

03.02.2026 16:47 πŸ‘ 9 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
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This is a powerful line of questioning from Senator Hassan and an outrageous answer from Director Bhattacharya.

"If there were disruptions then it is the responsibility of the researchers that were managing the patients, not the NIH" because "I ordered that ... there would be continuity of care."

03.02.2026 16:25 πŸ‘ 209 πŸ” 70 πŸ’¬ 12 πŸ“Œ 20

Bernie: do vaccines cause autism? Yes or no
Batt: not the measles one
Bernie: no no, not measles, vaccines
Batt, very demure: I have not seen any evidence that they do

03.02.2026 15:30 πŸ‘ 10 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

Batt, muttering: thebestwaytostopmeaslesepidemicisbyvaccination
Bernie, waving his arms: SAY IT LOUDER!

03.02.2026 15:28 πŸ‘ 17 πŸ” 4 πŸ’¬ 3 πŸ“Œ 0
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These peptides have not been shown to cure or treat anything. Safety hasn't been established. Yet, many of the people taking stacks of them, injecting into their bloodstream, are the same ones who are against vaccines. nymag.com/intelligence...

27.01.2026 17:04 πŸ‘ 227 πŸ” 67 πŸ’¬ 12 πŸ“Œ 6
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Alex Pretti’s coworkers hold a moment of silence for him.

Devastating and infuriating.

Nurses want peace.

26.01.2026 23:48 πŸ‘ 385 πŸ” 79 πŸ’¬ 4 πŸ“Œ 1
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Wife and I in tears reading this…

26.01.2026 04:30 πŸ‘ 276 πŸ” 97 πŸ’¬ 3 πŸ“Œ 4
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β€œIt's not bullying if I do it to everyone”: What are the red flags of a toxic healthcare workplace culture? #MedTwitter responses from UK NHS healthcare professionals – A qualitative study The study aimed to understand NHS healthcare workers’ perceptions of toxic organisational cultures and behaviours, by undertaking an analysis of tweet…

Organisational toxicity in healthcare: three years ago I asked #MedTwitter to share their red flags. We got hundreds of replies - the thread oozed pain. Three people offered to help write it up… our paper was published last week.

www.sciencedirect.com/science/arti...

Please share it πŸ™πŸΌ #MedSky

18.01.2026 17:23 πŸ‘ 37 πŸ” 18 πŸ’¬ 3 πŸ“Œ 6
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Association between vaccinations and risk of dementia: a systematic review and meta-analysis AbstractImportance. Dementia is a highly prevalent issue in older people. Whilst the prevention of dementia is a public health priority, the role of vaccin

academic.oup.com/ageing/artic...

18.01.2026 20:36 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Not good to see the rise in p-tau181, a marker of brain inflammation tied to increased risk of Alzheimer's disease, in a prospective cohort (mean age 56 years) with #LongCovid and neurological symptoms

www.thelancet.com/journals/ebi...

15.01.2026 02:19 πŸ‘ 253 πŸ” 96 πŸ’¬ 8 πŸ“Œ 9
Happy Hanukkah
Happy Hanukkah YouTube video by Zohran Mamdani for NYC

It was such a joy to celebrate Hanukkah with Mandy, Kathryn and their son, Gideon. As Jewish New Yorkers across our city prepare to light candles and mark the seventh night today, I wish you and your families a Hanukkah full of light and love.

youtu.be/KIxAKyioXng

20.12.2025 13:58 πŸ‘ 17905 πŸ” 2702 πŸ’¬ 330 πŸ“Œ 381
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Tween and teen looked at the 67th ASH Annual Meeting website and pointed out: 6 7 πŸ˜‚ #ASH25 @ash.hematology.org

07.12.2025 17:20 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Fantastic Ham-Wasserman lecture by Chiara Bonini on T cell engineering & gene editing - also a beautiful example of what mentorship / leadership should be - acknowledging her mentors and collaborators & especially highlighting the work of her many mentees #ash25 @ash.hematology.org

07.12.2025 14:52 πŸ‘ 8 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Sharing our trial in progress, IMPACT AL, testing teclistamab combined with daratumumab in newly diagnosed #alamyloidosis at #ASH25 meetin. Excited to work with Drs Chakraborty, Lentzsch, and Sanchorawala, with funding from J&J and SU2C.

06.12.2025 23:36 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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β€˜They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission Engineered T cells that have been used to treat ulcerative colitis, rheumatoid arthritis and lupus show promising results.

β€˜They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission www.nature.com/articles/d41...

29.11.2025 02:50 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The CDC Data Project In the proposed FY26 budget, programs that help Americans live safer, healthier, longer lives are on the chopping block.

New-to-me but very helpful visualizations how all the actions of the past ten months are affecting the CDC www.cdcdataproject.org

04.11.2025 19:41 πŸ‘ 54 πŸ” 31 πŸ’¬ 0 πŸ“Œ 7
This is figure 2, which shows temperature–mortality relationship across Europe.

This is figure 2, which shows temperature–mortality relationship across Europe.

A study in Nature Climate Change quantifies the potential for extreme heat events in Europe to generate mass mortality and projects tens of thousands of excess deaths. go.nature.com/483zJc3 πŸ§ͺ

21.11.2025 17:20 πŸ‘ 24 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
The order of the colored limes is a bit confusing so let's look at them in order from the bottom to the top.

The bottom line of square yellow dots shows the suicide death rates by firearms in the Democratic voting states by age as you follow that line you get the firearm suicide rates by age from age nine through age 84. The age group 85+ is excluded because it is hard to interpret because nobody lives through it. 

The pattern is generally followed by each of the groups, from age 9 through 22 the firearm suicide rate goes up. Then it sharply shifts to nearly level line that slightly increases up to age 55 when all but Democratic firearm suicides decline until about age 70  when the rate slightly more than  doubles at the end. 

Next, let's do  the line of green diamonds, the total Democratic voting states, their being lower at the right end actually makes them lower than the Republican voting states firearm suicides. 

They follow the same pattern as the Democrats by firearms except they decline from age 55 to about 70. Then they increase like the others but at a less steep rate in increase. 

Next to the top is  the Republican's suicides by firearms. They follow the  Democratic voting states almost exactly to age 20 then they edge down to bouncing between two and three points below the Democrats total until age 65 when they exhibit the steepest increase in the final years. 

The last line is the red diamonds for the Republican total which is consistently the highest. They follow the pattern of the total Democrat line of dots but generally get closer to the total Democratic line  at the end. 

Here are the two letter abbreviations for states:
Dem Mix Rep  
CA	AZ	AL
CO	GA	AK
CT	IA	AR
DE	MI	FL
DC	MN	ID
HI	NH	IN
IL	NC	KS
ME	OH	KY
MD	PA	LA
MA	TX	MS
NV	WI	MO
NJ	 	MT
NM		NE
NY		ND
OR		OK
RI		SC
VT		SD
VA		TN
WA		UT
		WV
		WY

The order of the colored limes is a bit confusing so let's look at them in order from the bottom to the top. The bottom line of square yellow dots shows the suicide death rates by firearms in the Democratic voting states by age as you follow that line you get the firearm suicide rates by age from age nine through age 84. The age group 85+ is excluded because it is hard to interpret because nobody lives through it. The pattern is generally followed by each of the groups, from age 9 through 22 the firearm suicide rate goes up. Then it sharply shifts to nearly level line that slightly increases up to age 55 when all but Democratic firearm suicides decline until about age 70 when the rate slightly more than doubles at the end. Next, let's do the line of green diamonds, the total Democratic voting states, their being lower at the right end actually makes them lower than the Republican voting states firearm suicides. They follow the same pattern as the Democrats by firearms except they decline from age 55 to about 70. Then they increase like the others but at a less steep rate in increase. Next to the top is the Republican's suicides by firearms. They follow the Democratic voting states almost exactly to age 20 then they edge down to bouncing between two and three points below the Democrats total until age 65 when they exhibit the steepest increase in the final years. The last line is the red diamonds for the Republican total which is consistently the highest. They follow the pattern of the total Democrat line of dots but generally get closer to the total Democratic line at the end. Here are the two letter abbreviations for states: Dem Mix Rep CA AZ AL CO GA AK CT IA AR DE MI FL DC MN ID HI NH IN IL NC KS ME OH KY MD PA LA MA TX MS NV WI MO NJ MT NM NE NY ND OR OK RI SC VT SD VA TN WA UT WV WY

Here I display single year age total and by firearm suicide death rates by single year age up to age 84 for Democratic and Republican voting states. |See text for more information. πŸ§ͺπŸ’‘β˜ οΈ #Sociology #Population #Republican #Democratic

16.11.2025 14:08 πŸ‘ 21 πŸ” 6 πŸ’¬ 2 πŸ“Œ 1
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Coevolution of cooperative lifestyles and reduced cancer prevalence in mammals While cooperative mammals evolve reducing cancer prevalence, oncogenes can be maintained by selection in competitive species.

Why do whales and elephants have much lower rates of cancer than expected?
"Species with a lower cancer prevalence and mortality
risk are those with a higher presence of cooperative and caring habits, while the opposite is found....:"
www.science.org/doi/10.1126/...

15.11.2025 16:43 πŸ‘ 239 πŸ” 61 πŸ’¬ 5 πŸ“Œ 7
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It is important for all myeloma clinicians to know about the CAR-T toxicities that occur outside of the acute post CAR-T period, such as non-ICANS neurotoxicities, second primary malignancies, and IEC-enterocolitis. ---Benjamin Puliafito, MD #IMS25

18.09.2025 15:37 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Join us in Hall FG at 2:00 PM to congratulate this year's #IMS25 award recipients!

18.09.2025 17:39 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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18.09.2025 19:13 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

STEM trial by Dr Cohen- use of sequential cevostamab after BCMA CAR-T- feasible, safe, associated with high efficacy #IMS25 Late Breaking Abstract

18.09.2025 19:13 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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IMS President Philippe Moreau exhorts researchers to submit their best original work, first reports of important clinical trials, to the IMS Annual Meeting- the largest myeloma-focused annual meeting. #IMS25

18.09.2025 13:53 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Grab your cuppa Tim Hortons- day 2 of #IMS25 in #toronto has begun with an educational session on relapsed myeloma management.

18.09.2025 12:04 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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#IMS2025 kicks off at Toronto, CA!

17.09.2025 12:42 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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We are getting ready for YOU! Here’s a first look inside #IMS25 πŸ‘€ It all begins tomorrow at 8:00 AM. See you soon!

16.09.2025 16:27 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0