Elodie Couderc

Collaborative work from @merklinglab.bsky.social and @lambrechtslab.bsky.social @pasteur.fr

So what’s your pick: traditional genetics 🧬 or innovative mosquitomics 🧪🔬? Let us know your thoughts!

In our latest review in @cp-trendsmicrobiol.bsky.social , we compare and discuss different strategies for decoding #vector #competence.

New #review out 🚨 for mosquito enthusiasts 🦟 !

Have you ever questioned the approach you routinely use to investigate #mosquito-virus #interactions? ⬇️

www.sciencedirect.com/science/arti...

Huge thanks to my mentors and all the collaborators of my PhD project
@merklinglab.bsky.social, @lambrechtslab.bsky.social, @pmiesen.bsky.social, @tompvial.bsky.social et al., who made this exciting work possible

Using an in vivo CRISPR/Cas9-mediated approach, we provide the first dynamic insight of a Vago-like gene’s function during #flavivirus infection of #Aedes #aegypti 🦠. Our findings suggest that VLG-1 supports #DENV and #ZIKV virus by promoting its dissemination throughout the mosquito’s body. 🤯

Vago genes are often assumed to function as antiviral cytokine analogs in arthropods 📖. We conducted a phylogenetic analysis of Vago-like genes in insects 🪰🦟🐝 and revealed a new Vago-like family 🆕

Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes - BMC Biology Background Arthropod-borne viruses (arboviruses) such as dengue virus (DENV) and Zika virus (ZIKV) pose a significant threat to global health. Novel approaches to control the spread of arboviruses foc...

🚀 Excited to share (with a little delay) my first first-author publication on #Vago genes in #mosquitoes! 🦟 🦠 Have a look to see how we questioned a mosquito immunity dogma and challenged the existing understanding of Vago-like genes as antiviral factors ⬇️

bmcbiol.biomedcentral.com/articles/10....