Alireza Modirshanechi's Avatar

Alireza Modirshanechi

@modirshanechi

Postdoc at Helmholtz Munich (Schulz lab) and MPI for Biological Cybernetics (Dayan lab) || Ph.D. from EPFL (Gerstner lab) || Working on computational models of learning and decision-making in the brain; https://sites.google.com/view/modirsha

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23.10.2023
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Latest posts by Alireza Modirshanechi @modirshanechi

How are neural manifolds and single-neuron response properties related to circuit structure?

How degenerate are these relationships?

Theory and a plethora of examples can be found in the following paper, out today in Neuron 🌟

It was a privilege to co-supervise first author @lpezon.bsky.social!

06.03.2026 23:01 πŸ‘ 53 πŸ” 13 πŸ’¬ 1 πŸ“Œ 0
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Linking neural manifolds to circuit structure in recurrent networks Neural population activity can be described either by low-dimensional dynamics on neural manifolds or by single-neuron selectivities. Using a theoretical approach, Pezon et al. relate these two statistical descriptions to circuit structure in recurrent networks. Their results reveal both degeneracies and specific constraints in how circuit structure shapes neural activity.
06.03.2026 16:23 πŸ‘ 37 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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Linking neural manifolds to circuit structure in recurrent networks Dimensionality reduction methods are widely used in neuroscience to investigate two complementary aspects of neural activity: the distribution of sing…

Excited to share our new paper to be published in Neuron!

With Valentin Schmutz @bio-emergent.bsky.social and Wulfram Gerstner @gerstnerlab.bsky.social, we explore how circuit structure in RNNs shapes network computation and single-neuron responses.
www.sciencedirect.com/science/arti...

06.03.2026 17:11 πŸ‘ 37 πŸ” 11 πŸ’¬ 1 πŸ“Œ 1
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Maternal information sampling targets children's knowledge gaps According to recent computational approaches, when children are presented with information by knowledgeable others, children can make the pedagogical …

New @sfb1528.bsky.social and @rtg2906-curiosity.bsky.social publication. We show that mothers are worthy of the pedagogical assumption: they preferentially sample information that fills their child's knowledge gaps and children learn best from maternal sampling: www.sciencedirect.com/science/arti...

27.02.2026 07:56 πŸ‘ 15 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1

After several years of work, my lab is starting to put out our first papers on learning in a unicellular organism (Stentor coeruleus).

Here we show evidence for a form of associative learning in Stentor:
www.biorxiv.org/content/10.6...

26.02.2026 11:39 πŸ‘ 176 πŸ” 57 πŸ’¬ 5 πŸ“Œ 7
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🚨New pre-print🚨

osf.io/preprints/ps...

What if the relationship between smartphone use and mental health depends not just on specific harmful or beneficial activities, but also on how users transition between activities?

24.02.2026 13:39 πŸ‘ 51 πŸ” 20 πŸ’¬ 3 πŸ“Œ 3

One week left to apply!

23.02.2026 14:27 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Agouti integrates environmental cues to regulate paternal behaviour - Nature Expression of agouti signalling protein in neurons in the medial preoptic area is increased by group housing and negatively associated with care, and overexpression of Agouti reduces care and enhances...

Why are some males caring toward infants while others are neglectful or abusive? I'm so pleased to share work that my colleagues and I @princeton.edu have just published @nature.com (an explanatory thread to follow!) (1/8)

18.02.2026 17:05 πŸ‘ 140 πŸ” 59 πŸ’¬ 9 πŸ“Œ 7
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Gene editing treats a mouse model of a neurodevelopmental disorder An approach that specifically targets a single nucleotide corrected behavioural abnormalities in an animal model of Snijders Blok–Campeau syndrome.

This gene editing approach specifically targets a single nucleotide corrected behavioural abnormalities in an animal model of Snijders Blok–Campeau syndrome

go.nature.com/40j3rX3

20.02.2026 14:09 πŸ‘ 23 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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🚨 Hiring in Munich πŸ‡©πŸ‡ͺ: 2 open-topic PhD positions in human & machine learning (TVΓΆD E13 80%).
Start ~June 2026 (flexible). Deadline: March 2, 2026.
Apply/info: hcai-munich.com/PhD_Job_Ad.pdf
Reposts appreciated πŸ™

05.02.2026 13:03 πŸ‘ 28 πŸ” 19 πŸ’¬ 1 πŸ“Œ 2
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I just did the dumbest thing of my entire career to prove a much more serious point.

I tricked ChatGPT and Google, and made them tell other users I’m a competitive hot-dog-eating world champion

People are using this trick on a massive scale to make AI tell you lies. I’ll explain how I did it

18.02.2026 16:37 πŸ‘ 4855 πŸ” 2138 πŸ’¬ 86 πŸ“Œ 304

Come and join us in beautiful Munich! 🧠
We have a friendly, collaborative, and inclusive environment, where scientific rigour and curiosity are celebrated. πŸŽ‰

#psychology #AI #intelligence #cogsci #neurosky #neuroskyence #ScienceCareer #AcademicJobs #Researcher #ResearchOpportunities #JobSearch

06.02.2026 08:04 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Come and join us in beautiful Munich! 🧠
We have a friendly, collaborative, and inclusive environment, where scientific rigour and curiosity are celebrated. πŸŽ‰

#psychology #AI #intelligence #cogsci #neurosky #neuroskyence #ScienceCareer #AcademicJobs #Researcher #ResearchOpportunities #JobSearch

06.02.2026 08:04 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Iranians are experiencing a collective trauma. Thousands have been killed/injured in recent events, the economy is crippled & the threat of a wider conflict is real. This is especially difficult for those living in Iran, as many have lost (or fear losing) loved ones. www.nature.com/articles/d41...

03.02.2026 14:11 πŸ‘ 70 πŸ” 32 πŸ’¬ 1 πŸ“Œ 7
Our model jointly learns object embeddings and idiosyncratic weightings of psychological dimensions.

Our model jointly learns object embeddings and idiosyncratic weightings of psychological dimensions.

The results show improved accuracy on hold-out data as well as reliably measurable dimensional weights (up to ~8 dimensions) and summary stats thereof

The results show improved accuracy on hold-out data as well as reliably measurable dimensional weights (up to ~8 dimensions) and summary stats thereof

Do people's internal representations of natural objects differ? We (@ericschulz.bsky.social) show so by incorporating idiosyncrasies into neural nets to create better models of human behavior. We also reliably extract idiosyncrasies and map them to demographics. More: osf.io/preprints/psyarxiv/pxt9a

03.02.2026 08:11 πŸ‘ 15 πŸ” 3 πŸ’¬ 1 πŸ“Œ 1
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These days I drink Iranian tea everyday so I don't forget.

Media coverage of these events have been very poor in my internet bubble so far.

26.01.2026 13:29 πŸ‘ 16 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Iran report says 16,500 dead in β€˜genocide under digital darkness’ β€” The Times and The Sunday Times β€˜You have ten minutes to cry,” came the officer’s curt command to the couple as he revealed the corpse of their twentysomething daughter, gunned down in the historic streets of Isfahan. After searchin...

New report from doctors shows the Iranian regime slaughtered 16,500 protesters during the communications shutdown.

18.01.2026 18:04 πŸ‘ 1152 πŸ” 793 πŸ’¬ 74 πŸ“Œ 103
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Trump’s Fateful Choice in Iran Taking military action is risky. Falsely encouraging freedom fighters would be shameful.

β€œIf Trump chooses not to act, his encouragement of the Iranian people to rise up, his repeated promises of U.S. support, and his subsequent abandonment of them will be remembered as one of the most callous examples of presidential betrayal in modern history”

www.theatlantic.com/internationa...

18.01.2026 16:09 πŸ‘ 11 πŸ” 3 πŸ’¬ 3 πŸ“Œ 1

estimates of the death toll in Iran is now >16000

18.01.2026 16:23 πŸ‘ 11 πŸ” 4 πŸ’¬ 2 πŸ“Œ 0

With some trepidation, I'm putting this out into the world:
gershmanlab.com/textbook.html
It's a textbook called Computational Foundations of Cognitive Neuroscience, which I wrote for my class.

My hope is that this will be a living document, continuously improved as I get feedback.

09.01.2026 01:27 πŸ‘ 585 πŸ” 237 πŸ’¬ 16 πŸ“Œ 10

I don't know enough to have my own view on this paper or response, but to me this is science social media at its best: doing post publication peer review of papers that make big claims. Bravo @alexanderhuth.bsky.social

05.01.2026 19:43 πŸ‘ 30 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

This paper had a pretty shocking headline result (40% of voxels!), so I dug into it, and I think it is wrong. Essentially: they compare two noisy measures and find that about 40% of voxels have different sign between the two. I think this is just noise!

05.01.2026 17:22 πŸ‘ 238 πŸ” 99 πŸ’¬ 8 πŸ“Œ 9

Please repost to get the word out! @nkgarg.bsky.social and I are excited to present a personalized feed for academics! It shows posts about papers from accounts you’re following bsky.app/profile/pape...

10.03.2025 15:12 πŸ‘ 164 πŸ” 117 πŸ’¬ 8 πŸ“Œ 13

πŸš€ Deadline for this is this Sunday! πŸƒβ€β™€οΈ

02.01.2026 09:40 πŸ‘ 5 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Leveraging insights from neuroscience to build adaptive artificial intelligence Nature Neuroscience - Adaptive intelligence envisions AI that, like animals, learns online, generalizes and adapts quickly. This Perspective reviews biological foundations, progress in AI and...

Interested in the latest advances in neuroscience (neural dynamics and internal models) and how they can be leveraged to build smarter, adaptive AI?

➑️ My first real solo piece πŸ–€πŸ«Ά @natneuro.nature.com

rdcu.be/eWVmA

31.12.2025 08:00 πŸ‘ 121 πŸ” 35 πŸ’¬ 5 πŸ“Œ 1
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Way back in 1999, Kenji Doya sketched a big picture theory of the brain:

1️⃣The cerebellum is specialized for supervised learning
2️⃣The basal ganglia are for reinforcement learning
3️⃣The cerebral cortex is for unsupervised learning

How does this hold up in 2026? www.sciencedirect.com/science/arti...

01.01.2026 15:36 πŸ‘ 37 πŸ” 10 πŸ’¬ 3 πŸ“Œ 1
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Rethinking the centrality of brain areas in understanding functional organization Nature Neuroscience - Parcellation of the cortex into functionally modular brain areas is foundational to neuroscience. Here, Hayden, Heilbronner and Yoo question the central status of brain areas...

New Perspective from myself, Sarah Heilbronner and @myoo.bsky.social . β€œRethinking the centrality of brain areas in understanding functional organization” in Nature Neuroscience. 🧡

rdcu.be/eVZ1A

23.12.2025 13:02 πŸ‘ 253 πŸ” 99 πŸ’¬ 9 πŸ“Œ 10
 Predicted hair cortisol concentration (pg/mg) by birth mode

Predicted hair cortisol concentration (pg/mg) by birth mode

A trending PNAS article in the last week is β€œEvolved birth physiology meets modern birth practice: Sustained effects of planned cesarean delivery on child hair cortisol in Brazil.” Explore now: https://ow.ly/Lj1550XNIgO

For more trending articles, visit https://ow.ly/oIyQ50XNIcn.

24.12.2025 02:00 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Antidepressant treatment shouldn't be a guessing game. RELMED is working towards using advanced research to predict which medication is most likely to help each person along their individual path to recovery.

Postdoctoral research position in #ComputationalPsychiatry and #EEG as part of relmed.ac.uk trial testing reinforcement learning as biomarker for antidepressant treatment response. www.ucl.ac.uk/work-at-ucl/... @uclbrainscience.bsky.social @mikebrowning.bsky.social @relmed.bsky.social

21.12.2025 21:40 πŸ‘ 32 πŸ” 29 πŸ’¬ 1 πŸ“Œ 1

Our paper is finally out in Nature Human Behavior!!
@epfl-brainmind.bsky.social

22.12.2025 11:21 πŸ‘ 10 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0