Institute of Systems, Molecular and Integrative Biology 's Avatar

Institute of Systems, Molecular and Integrative Biology

@livuni-ismib

Cutting-edge, interdisciplinary research and teaching in the biological sciences at the University of Liverpool. #TeamLivUni πŸ’» liverpool.ac.uk/systems-molecular-and-integrative-biology

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20.11.2024
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Latest posts by Institute of Systems, Molecular and Integrative Biology @livuni-ismib

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Exciting news! Artificial Intelligence will be used to accelerate new medicine discovery in a University of Liverpool partnership secured following Mayor Steve Rotheram’s US trade mission.

Read the full story ▢️ news.liverpool.ac.uk/2026/02/05/n...

05.02.2026 10:48 πŸ‘ 0 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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🌍 Sustainability Week 2026 is coming! πŸ™ŒπŸΎ

Join us from 23-27 Feb for our annual week of events, activities and opportunities for students and staff to get involved in sustainability.

Tap the link below or check the MyLiverpool app to explore the full programme!

πŸ”— www.liverpool.ac.uk/about/sustai...

03.02.2026 13:41 πŸ‘ 7 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

@liverpooluni.bsky.social | @livunichil.bsky.social | @lpoolcityregion.bsky.social | @lcrmayor.bsky.social |

15.01.2026 14:24 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Blood sugar spikes linked to higher risk of Alzheimer's disease - University of Liverpool News Blood sugar spikes linked to higher risk of Alzheimer's disease

A new study led by researchers from the Institute of Systems, Molecular and Integrative Biology has found that spikes in blood sugar after meals may increase the risk of Alzheimer’s disease.

Read the full story ▢️ news.liverpool.ac.uk/2026/01/14/b...

14.01.2026 15:27 πŸ‘ 8 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0

Resharing & please pass it on!

ACCE+ PhD project on the molecular evolution of insectivorous mammals that eat toxic amphibians πŸ¦”πŸΈ. Jointly supervised with brilliant colleagues in @livuni-ismib.bsky.social & @mpi-ce.bsky.social & open to UK & international students. @shabmohammadi.bsky.social

22.12.2025 15:00 πŸ‘ 8 πŸ” 12 πŸ’¬ 0 πŸ“Œ 0
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Wishing everyone a joyful and festive holiday season!

πŸŽ„The HLS social media elves are now taking a little break but we'll be back in 2026!

@livuni-ismib.bsky.social
@livuni-ives.bsky.social
@livuni-iph.bsky.social
@livuni-ilcams.bsky.social

19.12.2025 16:01 πŸ‘ 0 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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World-leading researcher, Professor William Hope has secured Β£8 million from Wellcome to tackle antimicrobial resistance (AMR), a leading global health threat responsible for millions of deaths worldwide.

Read more ▢️ news.liverpool.ac.uk/2025/12/18/8...

18.12.2025 14:01 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
A navy blue title card that reads 'Science Jamboree celebrates a decade of STEM fun and discovery' in white text against a transparent image of a group of scouts taking part in an activity involving balloons.

A navy blue title card that reads 'Science Jamboree celebrates a decade of STEM fun and discovery' in white text against a transparent image of a group of scouts taking part in an activity involving balloons.

We recently celebrated the tenth annual Science Jamboree, featuring STEM fun and discovery with members of our Faculty and our friends in the Faculty of Science and Engineering. Activities included planetarium stargazing, the chemistry of 'dragons snot' and more!

πŸ”— bit.ly/48ECa55

#TeamLivUni

08.12.2025 15:33 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

@lincneurosci.bsky.social

21.11.2025 14:42 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
 A navy blue title card that reads ' New tool helps predict which brain tumours will require treatment' in white text. Pictured to the left is a transparent human body image that shows the brain.

A navy blue title card that reads ' New tool helps predict which brain tumours will require treatment' in white text. Pictured to the left is a transparent human body image that shows the brain.

New clinical tool developed by @liverpooluni.bsky.social and The Walton Centre shown to accurately predict whether meningiomas will grow or cause symptoms, helping doctors and patients make better-informed treatment decisions.

πŸ”— bit.ly/47QP6G4

#TeamLivUni | #braintumour

21.11.2025 14:41 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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⭐️ Fantastic talk from Evangelos Giampazolias today at our Liverpool Cancer Seminar Series on nutrient-host-microbiome interactions in cancer immunity πŸ‘πŸ»πŸ‘πŸ»
@livuni-ismib.bsky.social
@livunicancer.bsky.social
@cruk-mi.bsky.social
@giampazolias.bsky.social

18.11.2025 16:39 πŸ‘ 10 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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@liverpooluni.bsky.social and @newcastleuni.bsky.social researchers have uncovered how bacterial organelles assemble, opening new routes for bioengineering and climate innovation.

πŸ‘‰ news.liverpool.ac.uk/2025/11/10/n...

14.11.2025 12:43 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Join a dynamic research team led by Dr Carrie Duckworth -
2 PhD fully funded studentships are available aligned with the recently established North West Cancer Research gastric cancer organoid hub!

#Biotechnology #BioEngineering #PhDpositions
#CellBiology #CancerBiology

15.11.2025 14:52 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Fully-funded PhD opportunities to tell you about at @livuni-ismib.bsky.social

1. I'm leading a project to translate protein bioinformatics tools to make the lives of structural biologists easier. Your supervisory team includes Igor Barsukov, Ronan Keegan and David McDonagh

lnkd.in/ePaFHGZD

12.11.2025 09:03 πŸ‘ 0 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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(BBSRC NWD) A novel redox mechanosignalling nexus in the synapse that is misregulated in neurodegeneration at University of Liverpool on FindAPhD.com PhD Project - (BBSRC NWD) A novel redox mechanosignalling nexus in the synapse that is misregulated in neurodegeneration at University of Liverpool, listed on FindAPhD.com

🧠 Fully funded 4-year PhD studentship 🧠 Please repost

BBSRC NWD project with @parikki.bsky.social and @iamabyron.bsky.social

Come join us to look at how mechanical and oxidative stress signalling pathways converge on the synaptic scaffold protein talin.

www.findaphd.com/phds/project...

11.11.2025 10:29 πŸ‘ 4 πŸ” 9 πŸ’¬ 1 πŸ“Œ 1
A photo from left to right of Mr Mushfique Alam, Dr Georges Chalhoub, Dr Carrie Duckworth, Mr Nathan Stephens and Professor Mark Pritchard in front of a 'Faculty of Health and Life Sciences' branded wall.

A photo from left to right of Mr Mushfique Alam, Dr Georges Chalhoub, Dr Carrie Duckworth, Mr Nathan Stephens and Professor Mark Pritchard in front of a 'Faculty of Health and Life Sciences' branded wall.

NEWS | North West Cancer Research supports study to improve gastric cancer outcomes

The project led by Dr Carrie Duckworth, entitled OrganoXplore, aims to develop personalised treatment strategies to reduce deaths from gastric cancer

πŸ”— bit.ly/4osEqTO

#TeamLivUni

11.11.2025 12:06 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation. Induced protein proximity offers powerful new routes to modulate protein fate. While proteolysis-targeting chimeras (PROTACs) promote degradation through E3 ligase recruitment, the converse principle-...

Our latest preprint is out!
We developed an inducible β€œRapTag” system that uses ENTAC to chemically recruit USP15 to the unstable protein CTLA4. This induced proximity stabilises and slows down the rapid lysosomal turnover of CTLA4.
@livuni-ismib.bsky.social
www.biorxiv.org/content/10.1...

10.11.2025 16:34 πŸ‘ 4 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Partnership with CyanoCapture Ltd to develop bionanotechnology for targeted drug delivery - University of Liverpool News Partnership with CyanoCapture Ltd to develop bionanotechnology for targeted drug delivery

@liverpooluni.bsky.social and CyanoCapture Ltd are joining forces to develop the next generation of carboxysome-based targeted drug delivery systems, exploiting unique traits found in fast-growing cyanobacteria.

Read more πŸ‘‰

news.liverpool.ac.uk/2025/10/30/p...

31.10.2025 16:36 πŸ‘ 0 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Our group in @livuni-ismib.bsky.social are delighted to share our latest article in Nature Reviews Drug Discovery:
lnkd.in/d_uXvxM2
In quantitative systems toxicology, the achievements of the @IHIeurope.bsky.social Innovative Health Initiative TransQST consortium in improving drug safety.

29.10.2025 15:25 πŸ‘ 4 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

@livuninews.bsky.social

28.10.2025 14:56 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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NEWS | A major UK-wide study led by Dr Carolyn Young has revealed the profound impact of multiple sclerosis on health-related quality of life, with findings that could reshape how services and resources are allocated for people living with the condition

πŸ”— bit.ly/4qBhovG

#TeamLivUni

28.10.2025 14:38 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
A teal news title card that reads 'BBSRC Northwest doctoral programme in biosciences welcomes first cohort’ in white text. Pictured in the top right is a photo of the 31 new students at the programme launch event.

A teal news title card that reads 'BBSRC Northwest doctoral programme in biosciences welcomes first cohort’ in white text. Pictured in the top right is a photo of the 31 new students at the programme launch event.

The BBSRC NorthWest DTP has welcomed its first postgraduate cohort. The programme is a joint initiative by @liverpooluni.bsky.social and @manchester.ac.uk to equip early-career scientists with the skills to tackle the UK’s key bioscience and environmental challenges.

πŸ”— bit.ly/48JGwK4

#TeamLivUni

27.10.2025 14:06 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Photo in my lab

Photo in my lab

Celebrating the first wet-lab experiment in my group. Successfully carried out by Sophie, my first MRes student and research assistant in Liverpool @liverpooluni.bsky.social, and me. Thanks to colleagues in the APT group of ISMIB @livuni-ismib.bsky.social for sharing their experience. #nanopore

24.10.2025 18:05 πŸ‘ 9 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
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Great to share our British Science Festival experience β€˜Liverpool’s Party People’ with @livuni-ismib.bsky.social colleagues this afternoon.

Thanks @drlornayoung.bsky.social for the photo

22.10.2025 17:30 πŸ‘ 4 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
A collage of two photos of PhD students Konstantinos Prokopidis (pictured left) and Theano Kyriakou (pictured right) from the Faculty of Health and Life Sciences.

A collage of two photos of PhD students Konstantinos Prokopidis (pictured left) and Theano Kyriakou (pictured right) from the Faculty of Health and Life Sciences.

Congratulations to Konstantinos Prokopidis from @livuni-ilcams.bsky.social and Theano Kyriakou from @livuni-ismib.bsky.social, who have received the prestigious Professor John Glover Memorial Award πŸŽ‰

➑️ bit.ly/42wwOXI

#TeamLivUni

15.10.2025 14:16 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
A sky blue quote social card that reads β€˜β€œWe hope that through targeted viral engineering, this work has the potential to broaden therapeutic applications, improve efficacy and underpin the development of the next generation of vaccines and gene therapies.” Dr Joshua Gardner, Department of Pharmacology and Therapeutics’ in white text. Pictured to the left is a photograph of Dr Joshua Gardner.

A sky blue quote social card that reads β€˜β€œWe hope that through targeted viral engineering, this work has the potential to broaden therapeutic applications, improve efficacy and underpin the development of the next generation of vaccines and gene therapies.” Dr Joshua Gardner, Department of Pharmacology and Therapeutics’ in white text. Pictured to the left is a photograph of Dr Joshua Gardner.

NEWS | Congratulations to Dr Joshua Gardner, who has received a five-year @wellcometrust.bsky.social Early-Career Award to support his research into how prior exposure to viruses can impact vaccine safety and performance

➑️ bit.ly/4mSKbbR

#TeamLivUni

10.10.2025 13:33 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Alt text: A navy blue news title card that reads 'Significant global variation in the treatment of common bowel condition' in white text against a transparent image of a man clutching his abdomen.

Alt text: A navy blue news title card that reads 'Significant global variation in the treatment of common bowel condition' in white text against a transparent image of a man clutching his abdomen.

NEWS | New research has shown significant global variation in the treatment of diverticulitis, a common bowel condition.

The Bowel Research UK funded study revealed the use of antibiotics to treat diverticulitis is 'alarmingly high'.

➑️ bit.ly/4gRjxPn

#TeamLivUni

03.10.2025 09:43 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Alt text: A navy blue news title card that reads 'New insights into how pathogens build protein machinery for survival in the gut' in white writing. Pictured to the right is a diagram of the digestive system with diagrams of gut bacteria.

Alt text: A navy blue news title card that reads 'New insights into how pathogens build protein machinery for survival in the gut' in white writing. Pictured to the right is a diagram of the digestive system with diagrams of gut bacteria.

New research has revealed how pathogenic bacteria construct tiny protein-based compartments, offering new insight into how bacteria survive and thrive in the gut.

➑️ bit.ly/476v5uz

#TeamLivUni

03.10.2025 09:31 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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NEWS I Scientists at @liverpooluni.bsky.social have developed a new low-cost blood test that could make it easier to detect #Alzheimer’s disease at an earlier stage. Read all about it ⬇️

news.liverpool.ac.uk/2025/10/01/l...

@livunihls.bsky.social @livuni-ismib.bsky.social

01.10.2025 11:18 πŸ‘ 12 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Join us for coffee & cake 🍰 β˜•
Macmillan Coffee Morning
Friday 26 September
10:00 - 11:00
2nd floor breakout area, William Henry Duncan Building

Raising funds for Macmillan Cancer Support. There will be tea, coffee and a variety of cakes and other treats to enjoy together.

25.09.2025 11:48 πŸ‘ 0 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0