Lori Benedict BSN RN CDCES CMES

@AmDiabetesAssn names superb scientists recipients of the 2026 Banting Medal, Prof Takashi Kadowaki, and the Outstanding Scientific Achievement Award, Prof Timo Müller
www.prnewswire.com/news-release...

Screen shot of a phone display for refrigerator named “Coolio”

I named my refrigerator “Coolio”

Photo of penguins on the sand with water in the background. One penguin in the forefront standing on a mound of snow looks suspicious

I did not have this on my 2026 bingo card

GPR75 in glutamatergic neurons regulates body weight Wyler, S.C. et al. identify a critical neuronal population that is required for GPR75 to exert its obesogenic effects using targeted deletion and reactivation of Gpr75 in glutamatergic neurons.

Studies in mice demonstrate the importance of glutamatergic neurons in GPR75’s regulation of food intake and protection from #obesity www.cell.com/cell-reports...

Screenshot from phone app that displays refrigerator name “Coolio”

My refrigerator’s name is Coolio

Figure showing the effect of statin versus placebo on events listed in statin SmPCs, subdivided by component parts. Results for two outcomes with fewer than ten events are not shown in the figure, but are included in the appendix. FDR=false discovery rate. LFT=liver function test. RBC=red blood cell. RR=rate ratio. SmPC=Summary of Product Characteristics. *FDR significant at the 5% level; RR for results FDR-significant at the 5% level are indicated by black circles and RR for results not FDR-significant at the 5% level indicated by grey circles. †Excluded from FDR testing; RR for results excluded from FDR testing indicated by white circles.

Almost all side effects on statin labels not caused by statins, finds major meta-analysis; authors call for labels to be updated.

Find out more 👉 spkl.io/63324AsjHO

Heads are going to explode 💥

Cato Institute just nuked the lie. Immigrants have cut U.S. deficits by $14.5 TRILLION since 1994, slashing the national debt by a third.

All that “immigrants are bleeding us dry” noise? Absolute bullshit.
1/3

❤️

Photo of large T-Rex dinosaur in front of a house

Winter storm warning in #RVA
Remember, if you’re cold they’re cold, bring pets inside.

Screenshot of men’s bluejean bikini banana hammock swimsuit on sale from swim outlet

A.I. we know everything about you and will send you targeted advertisements

Samuel Alito flew two flags used by insurrectionists.

Clarence Thomas' wife plotted to overturn the 2020 election.

Both justices refused to recuse themselves from SCOTUS cases related to the January 6th plot.

It's a stain on our nation that this has effectively been forgotten.

It's an old and obvious pattern. An unpopular president - failing on the economy and losing his grip on power at home - decides to launch a war for regime change abroad.

The American people don’t want to “run” a foreign country while our leaders fail to improve life in this one.

The expanding landscape of GLP-1 medicines - Nature Medicine This Review discusses the expansion of glucagon-like peptide-1 (GLP-1) medicines beyond type 2 diabetes and obesity, outlining opportunities for new indications, key questions around benefits and long...

2026 will bring waves of innovation to GLP-1 medicines from mechanisms to modalities to molecules delivery systems and new indications. #weightloss #obesity A glimpse of the.future here www.nature.com/articles/s41...

Single-cell perturbations decipher ribosomal stress-surveillance regulators in type 2 diabetes - Nature Metabolism The authors use Perturb-seq analysis in human pancreatic islet beta cells, as well as in vivo and in vitro analyses, to identify potential therapeutic targets for type 2 diabetes, including ZZEF1, whi...

By extensive molecular and genetic analyses of #insulin production and T2D pathology in human pancreatic β  (EndoC-βH1) cells and related models, the authors provide potential therapeutic targets for #T2D #genetics www.nature.com/articles/s42...

Sending good vibes your way

me dressed up and exercising at the airport before my 8 hour flight

A flyer for the event says: Patina Studies December 6th, 2025 1 Columbus Avenue San Francisco, CA 1pm-6pm

If you're in San Francisco, there's a pop-up market this Saturday at 1 Columbus Ave. A bunch of menswear guys, along with shop owners, are selling stuff from their private wardrobes. Some of my stuff will be there. Ticket prices are $30 for 12pm-1pm preview hour, then $5 after 1pm.

Will blockbuster obesity drugs revolutionize addiction treatment? Scientists are testing whether GLP-1 drugs can help to cut cravings for cigarettes, alcohol and opioids — as well as food.

After disappointments in neurodegenerative disorders #Parkinsons #AlzheimersDisease will GLP-1 medicines prove useful with an effective safety and efficacy profile in substance use disorders? www.nature.com/articles/d41... 🧪

Effects of CT-388, a once-weekly signaling-biased dual GLP-1/GIP receptor agonist, on weight loss and glycemic control in preclinical models and participants with obesity Biased agonism of the glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide receptors (GLP-1R/GIPR) yields greater weight loss and bett…

Some new preclinical and clinical data for CT-388, a once weekly cAMP signal-biased dual GLP-1R/GIPR agonist with minimal GLP-1R/GIPR internalization #obesity #weightloss www.sciencedirect.com/science/arti... 🧪

💙💛💙💛💙💛💛

Bridging the variant-to-function gap in type 2 diabetes: advances and challenges - Diabetologia Type 2 diabetes is a polygenic, heterogeneous disease affecting over 530 million individuals worldwide, a number projected to rise to 1.3 billion by 2050. Genome-wide association studies have identifi...

On the cusp of closing the genetic association and mechanism gap while laying the foundation for future precision medicine approaches in type 2 #diabetes #genetics @diabetologiajnl.bsky.social link.springer.com/article/10.1...

when I need relief from *gestures everywhere* the dumpster fire I go to Jerryland for a dose of laughter medicine

thanks Jer

Old time appearing illustration of Jesus on a bike in the snow pulling a sled with a Christmas tree lying on its side

this is the year I send out holiday cards

Reporters must stop accepting this. Options:

-Laughing at him. Long and hard (combine with others)
-"It's your job to be informed"
-"How can Americans take you seriously when you always claim ignorance?"
-"I've never heard a speaker claim ignorance so often"
-"Nancy Pelosi knew what was happening"

Fingers crossed🤞

KDIGO 2025 IgA guidelines - Visual Abstract — NephJC KDIGO 2025 is here. IgAN management is evolving with precision risk tools, new therapies, and a stronger focus on kidney protection. Check out the visual abstract created by Natalia Nombera

⏩ Next #NephJC is on IgA nephropathy @kdigo.org guideline

🎨 Nice visual summary by @roxnonna23.bsky.social

www.nephjc.com/news/2025/10...

I Don't Know How To Explain To You That You Should Care About Other People Our disagreement is not merely political, but a fundamental divide on what it means to live in a society.

This 2017 HuffPo piece contains more wisdom & insight on current politics than 1000000 consultant polling reports.

Weight‐reducing treatments are associated with an improvement in depression, functional health status, and quality of life: A meta‐analysis of randomized controlled trials Aim To assess whether there is a beneficial or detrimental effect of weight reduction on mental health. Materials and methods Meta-analysis of randomized trials performed for weight loss, in which.....

Turns out that if you lose weight you feel better dom-pubs.onlinelibrary.wiley.com/doi/10.1111/...