Joshua Jacobs

Registration and Abstract submission are now open for #iNAV2026! Join us in beautiful Banff for what promises to be a thought-provoking conference featuring loads of exciting research. And please consider presenting your own work as a data blitz talk or poster presentation!
www.inavsymposium.com

I have moved my lab to @uchicago! Really excited to be here and collaborate with all the wonderful scientists and clinicians here.

Movie-watching evokes ripple-like activity within events and at event boundaries Nature Communications - The neural processes involved in memory formation for realistic experiences remain poorly understood. Here, the authors found that ripple-like activity in the human...

🧠 Paper out!

We investigated how hippocampal and cortical ripples support memory during movie watching. We found that:

🎬 Hippocampal ripples mark event boundaries
🧩 Cortical ripples predict later recall

Ripples may help transform real-life experiences into lasting memories!

rdcu.be/eui9l

Cholinergic blockade reveals role for human hippocampal theta in encoding but not retrieval Cholinergic dysfunction is a hallmark of Alzheimer's disease and other memory disorders. Yet, the neurophysiological mechanisms linking cholinergic signaling to memory remain poorly understood. In thi...

Hi Bluesky! First post here. Kicking things off with a new preprint.

🧠 Using human iEEG + pharmacology, we asked: is hippocampal theta required for retrieval?

Turns out it’s not. Instead, it may reflect a reinstated encoding mode.

Thread below.
www.biorxiv.org/content/10.1...

The direction and timing of theta and alpha traveling waves modulate human memory processing To support a range of behaviors, the brain must flexibly coordinate neural activity across widespread brain regions. One potential mechanism for this coordination is a traveling wave, in which a neura...

this is really cool, Earl! We saw something similar in humans. It was mentioned in this preprint, Figures 5&6. But unfortunately this result didn't make it into the final version of the paper. www.biorxiv.org/content/10.1...

Please come to our Wave Club meeting tomorrow, April 1, at 12pm ET!

Our presenter is Dr. Jon Kleen (UCSF), who will discuss traveling waves in the human hippocampus from microgrids. All are welcome! Register here: forms.gle/5Q4CPqTHAchH...

We're thrilled to have Arif Hamid speak next week about spatiotemporal dopamine waves that support reinforcement learning at our online monthly seminar series! Join us on March 4th at 12-1p ET!
@arifahamid.bsky.social

We're thrilled to resume our monthly seminar on neural traveling waves in February with Andrea Alamia! Join us on
February 4th at 12-1p ET!

Join us tomorrow for this exciting talk! Register for the mailing list or DM us for the zoom link
t.co/cvl42Ma9GG