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Samantha Wellington Miranda

@drsamwellie

Here for the science. Postdoc researching bacterial communication @UW. Chemical biology, microbiology, infectious diseases. Health & housing equity.

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01.10.2023
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Latest posts by Samantha Wellington Miranda @drsamwellie

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The Cystic-Fibrosis Breakthrough That Changed Everything The disease once guaranteed an early deathβ€”but a new treatment has given many patients a chance to live decades longer than expected. What do they do now?
07.03.2024 23:29 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1

Read the latest Microbial Primer from the Microbiology Society on Bacterial Growth Kinetics www.microbiologyresearch.org/content/micr...

06.03.2024 12:42 πŸ‘ 11 πŸ” 7 πŸ’¬ 0 πŸ“Œ 2
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Adaptive Evolution of Pseudomonas aeruginosa in Human Airways Shows Phenotypic Convergence Despite Diverse Patterns of Genomic Changes Abstract. Selective forces in the environment drive bacterial adaptation to novel niches, choosing the fitter variants in the population. However, in dynamic an

Adaptive Evolution of Pseudomonas aeruginosa in Human Airways Shows Phenotypic Convergence Despite Diverse Patterns of Genomic Changes academic.oup.com/mbe/article/... #MicroSky

03.03.2024 21:12 πŸ‘ 13 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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Basic science is not just a foundation - Nature Cell Biology Intellectual freedom for scientists, unconstrained by commercial interests and direct application, fuels unexpected discoveries. Curiosity-driven, basic science has yielded a deeper understanding of h...

β€œCuriosity-driven, basic science has yielded a deeper understanding of how life forms develop and function in their environment and has had wide implications for health and our planet. Investing in this is vital for scientific progress and is worth protecting in a democracy.” β€”Ruth Lehmann

17.01.2024 00:18 πŸ‘ 52 πŸ” 29 πŸ’¬ 1 πŸ“Œ 1

Are you an early-stage researcher seeking support to attend ASM Microbe? πŸ§ͺ🧬

The ASM Peggy Cotter Travel Award Program provides funds for outstanding early career Branch members to attend ASM Microbe.

asm.org/Travel-Award...

13.01.2024 16:51 πŸ‘ 26 πŸ” 27 πŸ’¬ 1 πŸ“Œ 1
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SOCfinder: a genomic tool for identifying social genes in bacteria Bacteria cooperate by working collaboratively to defend their colonies, share nutrients, and resist antibiotics. Nevertheless, our understanding of these remarkable behaviours primarily comes from stu...

Our new tool 'SOCfinder' to find social genes in bacteria is out now, in Microbial Genomics 🦠

www.microbiologyresearch.org/content/jour...

29.12.2023 15:57 πŸ‘ 32 πŸ” 18 πŸ’¬ 0 πŸ“Œ 0

New biosurfactant alert! We report that some Burkholderia species can produce methylated rhamnolipids, which are thus nonionic. Lack of charge of these methyl esters might have major implications for their biological functions, and future applications www.sciencedirect.com/science/arti...

05.12.2023 16:21 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

The journal Microbiology, published by the Microbiology Society, is looking to appoint two new Senior Editors to help shape panels in regulation, sensing & signalling and eukaryotic microbiology. Join us in advancing microbiological research. Express your interest: microb.io/3sUvKyh

05.12.2023 16:28 πŸ‘ 22 πŸ” 41 πŸ’¬ 0 πŸ“Œ 0

These two types of competition (kin and interspecies) may work together to tune signal sensitivity.

05.12.2023 14:22 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Using quorum sensing in Pseudomonas aeruignosa, we find signal sensitivity impacts the timing and level of gene activation. Signal hypersensitivity results in a defect in kin competition while hyposensitivity reduces fitness during interspecies competition.

05.12.2023 14:21 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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A balancing act: investigations on the impact of altered signal sensitivity in bacterial quorum sens... Quorum sensing (QS) is a widespread form of cell-cell signaling that regulates group behaviors important for competition and cooperation within bacterial communities. The QS systems from different bac...

I'm thrilled to share our latest paper out in the Journal of Bacteriology! We asked the question: Which evolutionary pressures tune sensitivity in cell signaling?

doi.org/10.1128/jb.0...

05.12.2023 14:19 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Widespread fungal-bacterial competition for magnesium enhances antibiotic resistance bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Excited to share this manuscript by @hsiehyp.bsky.social, describing how Candida albicans sequesters magnesium from Pseudomonas aeruginosa, reducing bacterial fitness. But this competition has the effect of conferring colistin resistance on P. aeruginosa! /1

www.biorxiv.org/content/10.1...

31.10.2023 01:11 πŸ‘ 6 πŸ” 1 πŸ’¬ 3 πŸ“Œ 0
Mycobacterium tuberculosis colonies [source: https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis]

Mycobacterium tuberculosis colonies [source: https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis]

Latent Mycobacterium tuberculosis Infections
by Roberto
A quarter of the world's population – that's two billion people – is estimated to be latently infected with Mycobacterium tuberculosis. This staggering number is often presented in scientific pub...
Read more > tinyurl.com/2rarexkr
#MicroSky 🦠🧫

19.10.2023 09:02 πŸ‘ 16 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1

Funded PhD position in my group: Evolution of resistance to novel antibiotics. Academic/industrial project in collaboration with Bactobio. Excellent opportunity to do interesting fundamental science and learn from academic and commercial settings.
www.findaphd.com/phds/project...

17.10.2023 09:45 πŸ‘ 14 πŸ” 15 πŸ’¬ 0 πŸ“Œ 1
Science | AAAS

Tracking down why what’s supposed to be the same bacterial growth medium can give such different results: an unexpected impurity!

16.10.2023 15:51 πŸ‘ 33 πŸ” 17 πŸ’¬ 2 πŸ“Œ 2

Starting now-ish in the IDWeek poster hall!

12.10.2023 16:06 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0