#BioTechnology

1 hour ago

Build with DNA hands-on science event with colorful DNA helix icon — Saturday 21 March, 10:00am–2:00pm

Make your own DNA friendship bracelet 🧬

Get creative with DNA and discover how its structure allows it to store and share the code of life.

Explore the full programme at the link below 👇

🧪⚙️🌱🔋

#ChemicalEngineering #Biotechnology #CambridgeUniversity #CamFest

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WAVE-based intensified perfusion cell culture for fast process development - PubMed The study demonstrated the feasibility of using the WAVE-based rocking type bioreactor in the N stage IPC process, which increases the flexibility in adopting IPC process. The results suggest that the rocking type bioreactor system could be a viable alternative to traditional stirred tank bioreactor …

4 hours ago

🧫 WAVE-based intensified perfusion cell culture for fast process development.
Biotechnology letters(2023)
#Biotechnology #Science

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Spatial Proteomics Reveals Differences in the Cellular Architecture of Antibody-Producing CHO and Plasma Cell-Derived Cells - PubMed Most of the recombinant biotherapeutics employed today to combat severe illnesses, for example, various types of cancer or autoimmune diseases, are produced by Chinese hamster ovary (CHO) cells. To meet the growing demand of these pharmaceuticals, CHO cells are under constant development in order to …

9 hours ago

📚 Spatial Proteomics Reveals Differences in the Cellular Architecture of Antibody-Producing CHO and Plasma Cell-Derived Cells.
Molecular & cellular proteomics : MCP(2022)
#Biotechnology #Science

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Florian Graichen

@floriangraichen.bsky.social

14 hours ago

#bioprocessing #biotechnology #fermentation #biomanufacturing #bioeconomy #circularbioeconomy #biotechnz #innovationnz #lifesciences #biotechevents | Florian Graichen Rotorua will host of New Zealand’s key bioprocessing events this May - and registrations are now open. On 13 May, the NZ Bioprocessing Forum hosted by the The Bioprocessing Network will bring togeth...

Rotorua will host of New Zealand’s key bioprocessing events this May - and registrations are now open.
#biotechnology #bioeconomy
www.linkedin.com/posts/floria...

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Florian Graichen

@floriangraichen.bsky.social

14 hours ago

#biotechnology #bioeconomy #science #innovation #research | Florian Graichen Thank you to BioTech New Zealand for an incredible three days at the Life Sciences Summit - what an atmosphere, and what inspiring conversations! It was exciting to showcase the Bioeconomy Science Ins...

Special thanks to BioTech New Zealand for hosting us at the Life Sciences Summit this week.
#biotechnology #bioeconomy
www.linkedin.com/posts/floria...

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Next-generation cell line selection methodology leveraging data lakes, natural language generation and advanced data analytics - PubMed Cell line development is an essential stage in biopharmaceutical development that often lies on the critical path. Failure to fully characterise the lead clone during initial screening can lead to lengthy project delays during scale-up, which can potentially compromise commercial manufacturing succe …

16 hours ago

🌱 Next-generation cell line selection methodology leveraging data lakes, natural language generation and advanced data analytics.
Frontiers in bioengineering and biotechnology(2023)
#Biotechnology #Science

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Quantification of glycated IgG in CHO supernatants: A practical approach - PubMed Post-translational, nonenzymatic glycation of monoclonal antibodies (mAbs) in the presence of reducing sugars (in bioprocesses) is a widely known phenomenon, which affects protein heterogeneity and potentially has an impact on quality, safety, and efficacy of the end product. Quantification of indiv …

22 hours ago

🌱 Quantification of glycated IgG in CHO supernatants: A practical approach.
Biotechnology progress(2021)
#Biotechnology #Science

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Department of Chemical Engineering and Biotechnology, Cambridge

@novogene-europe.bsky.social

1 day ago

Colorful abstract background with banner reading "The art of eco-conscious colour" and event details: Saturday 21 March, 10am–2pm.

The art of eco-conscious colour 🌈

Artist-in-residence Diana Scarborough explores how art and science can work together to create colour without cost to the planet.

Explore the full CamFest programme below 👇

🧪⚙️🌱🔋

#ChemicalEngineering #Biotechnology #CamFest

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Novogene Europe

1 day ago

Discover high-res #singlecell gene expression and #immuneprofiling with 5' GEX #scRNA-seq. Integrated #transcriptomics with expert support from sample prep to data interpretation.

#5PrimeGEX #Genomics #NGS #Bioinformatics #LifeSciences #Biotechnology #PrecisionMedicine https://tinyurl.com/ye23687s

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BioResire Research Labs

@bioresireresearch.bsky.social

1 day ago

Types of ELISA Quick Lab Guide from BioResire!
Direct, Indirect, Sandwich, Competitive—master antigen/antibody detection methods.

#ELISA #TypesOfELISA #SandwichELISA #IndirectELISA #DirectELISA #CompetitiveELISA #Immunology #Biotechnology #Biochemistry #LabTechniques #BioResire #Diagnostics

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Cell Engineering and Cultivation of Chinese Hamster Ovary Cells for the Development of Orthogonal Eukaryotic Cell-free Translation Systems - PubMed The investigation of protein structures, functions and interactions often requires modifications to adapt protein properties to the specific application. Among many possible methods to equip proteins with new chemical groups, the utilization of orthogonal aminoacyl-tRNA synthetase/tRNA pairs enables …

1 day ago

📈 Cell Engineering and Cultivation of Chinese Hamster Ovary Cells for the Development of Orthogonal Eukaryotic Cell-free Translation Systems.
Frontiers in molecular biosciences(2022)
#Biotechnology #Science

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BioResire Research Labs

@bioresireresearch.bsky.social

1 day ago

Chromatography Quick Lab Guide by BioResire!
Separate biomolecules via stationary/mobile phases in paper, TLC, column, HPLC.
Internships open: info@bioresire.in #Chromatography #HPLC #TLC #Biochemistry #MolecularBiology #LabTechniques #Biotechnology #BioResire #AnalyticalChemistry #LabEquipment

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Deciphering Metabolic Pathways in High-Seeding-Density Fed-Batch Processes for Monoclonal Antibody Production: A Computational Modeling Perspective - PubMed Due to their high specificity, monoclonal antibodies (mAbs) have garnered significant attention in recent decades, with advancements in production processes, such as high-seeding-density (HSD) strategies, contributing to improved titers. This study provides a thorough investigation of high seeding p …

1 day ago

📚 Deciphering Metabolic Pathways in High-Seeding-Density Fed-Batch Processes for Monoclonal Antibody Production: A Computational Modeling Perspective.
Bioengineering (Basel, Switzerland)(2024)
#Biotechnology #Science

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Physiology of Yeasts and Filamentous Fungi

@pyff-9.bsky.social

1 day ago

🎤 Keynote Spotlight at #PYFF9!
We’re thrilled to welcome Paola Branduardi (Univ. Milano‑Bicocca), a leading expert in microbial #biotechnology, #synthetic biology & #biorefineries.
Don’t miss her keynote in Valencia!
#Valencia2026

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Single-stage chromatographic clarification of Chinese Hamster Ovary cell harvest reduces cost of protein production - PubMed A single-stage clarification was developed using a single-use chromatographic clarification device (CCD) to recover a recombinant protein from Chinese Hamster Ovary (CHO) harvest cell culture fluid (HCCF). Clarification of a CHO HCCF is a complex and costly process, involving multiple stages of cent …

1 day ago

💊 Single-stage chromatographic clarification of Chinese Hamster Ovary cell harvest reduces cost of protein production.
Biotechnology progress(2023)
#Biotechnology #Science

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Machine Learning Models Identify New Inhibitors for Human OATP1B1 - PubMed The uptake transporter OATP1B1 (SLC01B1) is largely localized to the sinusoidal membrane of hepatocytes and is a known victim of unwanted drug-drug interactions. Computational models are useful for identifying potential substrates and/or inhibitors of clinically relevant transporters. Our goal was t …

1 day ago

💻 Machine Learning Models Identify New Inhibitors for Human OATP1B1.
Molecular pharmaceutics(2022)
#Biotechnology #Science

1 0 1 0

@carlus-2024.bsky.social

1 day ago

A new strategy could intercept pancreatic cancer before it even appears.
✔🙂 Another encouraging news from Groupe UIG.
Read: lnkd.in/eeK5jqkb
#PancreaticCancer #Oncology #ScientificResearch #Biotechnology #PrecisionMedicine #HealthInnovation #EarlyDetection

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School of Pharmacy & Biomolecular Sciences at LJMU

@ljmupbs.bsky.social

2 days ago

FameLab North West Final Get ready for an unforgettable night of big ideas and brilliant science! The North West Final of FameLab is coming to Liverpool!

Two members of our school are in the North West final of #FameLab. Dr Gavin McStay @gavinmcstay.bsky.social, senior lecturer in #biotechnology, and Cherene de Bruyne, #PhD student in #forensic science, will be talking about their research. Free tickets here www.eventbrite.com/e/famelab-no...

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Department of Chemical Engineering and Biotechnology, Cambridge

@byteandpieces.bsky.social

2 days ago

Toothpaste for elephants...? 🐘

Get hands-on with fundamental science at our Cambridge Festival Open Day.

📅Saturday 21 March
🕙10:00am - 2:00pm

Book your place at the link in our bio 🔗

🧪⚙️🌱🔋

#CamFest #CambridgeUniversity #ChemicalEngineering #Biotechnology

3 1 2 0

2 days ago

Shape-shifting ALIENS & Skinwalker Ranch: Travis Walton, DNA Secrets, and Human Infiltration Ever felt like you're being watched by something... not quite human? Welcome to the frontline of Non-Human Intelligence (NHI) research. In this episode, we peel back the layers of the mimicry phenomenon to ask the ultimate question: Are we sharing our cities with shape-shifting extraterrestrials? From the terrifying Travis Walton abduction to the interdimensional bleed-over at Skinwalker Ranch, we investigate the evidence-based reality of extraterrestrial infiltration. What you'll discover: - The Mimic Protocol: Why the beings Walton saw wore human masks to pacify their captives. - Portal Guardians: The truth about the Navajo Skinwalker and DNA manipulation shamans. - The Avian Connection: How Thoth the Atlantean and Carian extraterrestrials provided the genetic blueprints for modern medicine. - The Hitchhiker Effect: Why these entities don't just stay at the ranch—they follow you home. We bridge the gap between Ancient Astronaut Theory and Modern Genetic Science, exploring bio-synthetic drone bodies and epigenetic memory. Is Skinwalker Ranch a 1.6 GHz beacon for trans-dimensional biology? Or are we part of a long-term human-alien hybridization project overseen by avian deities? Seriously, the truth is way weirder than the movies. Stop looking at the stars and start looking at the person next to you. Subscribe now to join the disclosure movement and uncover the declassified truth of our non-linear history. Join the conversation and share this episode to wake up the world!

📣 New Podcast! "Shape-shifting ALIENS & Skinwalker Ranch: Travis Walton, DNA Secrets, and Human Infiltration" on @Spreaker #alienabduction #ancientaliens #biotechnology #disclosure #extraterrestrial #geneticengineering #interdimensional #metaphysics #mystery #nhi #nonhumanintelligence #portal

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In-line buffer exchange in the coupling of Protein A chromatography with weak cation exchange chromatography for the determination of charge variants of immunoglobulin G derived from chinese hamster ovary cell cultures - PubMed Immunoglobulin G (IgG) is the most common monoclonal antibody (mAb) grown for therapeutic applications. While IgG is often selectively isolated from cell lines using protein A (ProA) chromatography, this is only a stepping stone for complete characterization. Further classification can be obtained f …

2 days ago

🧪 In-line buffer exchange in the coupling of Protein A chromatography with weak cation exchange chromatography for the determination of charge variants of immunoglobulin G de…
Journal of chromatography. A(2024)
#Biotechnology #Science

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The Innovation

@theinnovation.bsky.social

2 days ago

Deng et al. propose cell editing—a technology inspired by endosymbiosis—for implementing complex functions into a host chassis that are currently difficult or impossible to achieve.
doi.org/10.59717/j.x...
#LifeSciences #syntheticbiology #cellediting #biotechnology

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N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling - PubMed Cell surface proteins carrying N-glycans play important roles in inter- and intracellular processes including cell adhesion, development, and cellular recognition. Dysregulation of the glycosylation machinery has been implicated in various diseases, and investigation of global differential cell surf …

2 days ago

🧬 N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling.
International journal of molecular sciences(2022)
#Biotechnology #Science

1 0 1 0

Analysis of fouling and breakthrough of process related impurities during depth filtration using confocal microscopy - PubMed Titer improvement has driven process intensification in mAb manufacture. However, this has come with the drawback of high cell densities and associated process related impurities such as cell debris, host cell protein (HCP), and DNA. This affects the capacity of depth filters and can lead to carryov …

2 days ago

💻 Analysis of fouling and breakthrough of process related impurities during depth filtration using confocal microscopy.
Biotechnology progress(2022)
#Biotechnology #Science

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Alice Frolov

@alicefrolov.bsky.social

2 days ago

RFLP: the OG of DNA fingerprinting 🔬

Restriction enzymes cut DNA → fragments separate by size → unique pattern emerges

Outdated tech? Maybe. But the principles — leveraging natural variation for identification—still guide genomics today

#MolecularBiology #DNAFingerprinting #Biotechnology #RFLP

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BioResire Research Labs

@bioresireresearch.bsky.social

2 days ago

Restriction Enzymes Quick Lab Guide by BioResire!
Type II like EcoRI & HindIII cut DNA precisely for cloning & gene mapping.
Internships
info@bioresire.in
#RestrictionEnzymes #RestrictionEndonucleases #TypeIIRE #EcoRI #HindIII #MolecularBiology #Biotechnology #Cloning #GeneticEngineering

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Department of Chemical Engineering and Biotechnology, Cambridge

2 days ago

Workshop tools with teal banners announcing Davidson Inventors Challenge Final on Thursday 26 March, two weeks to go.

Only two weeks to go until the 2025/26 Davidson Inventors Challenge final! 🔧

See what the next generation of innovators can do!

Find out more at the link below 👇

🧪⚙️🌱🔋

#ChemicalEngineering #Biotechnology #CambridgeUniversity #Davidsoninventorschallenge

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Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation - PubMed Chinese Hamster Ovary (CHO) cells have rapidly become a cornerstone in biopharmaceutical production. Recently, a reinvigoration of perfusion culture mode in CHO cell cultivation has been observed. However, most cell lines currently in use have been engineered and adapted for fed-batch culture method …

2 days ago

📈 Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation.
Biotechnology and bioengineering(2024)
#Biotechnology #Science

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Department of Chemical Engineering and Biotechnology, Cambridge