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Posts tagged #GENOME

#ClinicalAudit Awareness Week shows why collaboration, data, and innovation matter. At #Genome we empower #HealthcareTeams to turn insight into better outcomes 💙 Get involved, share your work, and celebrate data‑driven improvement!
🗓️ 22–26 Jun 2026 ‪
#CAAW26 #NQICAN

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The complete genome of the golden lancehead reveals how genes responsible for venom toxins evolved One of the most complete sequencing projects ever performed on snakes worldwide serves as a reference for all jararaca vipers, which may contribute to new discoveries about toxins and the conservation of the species on Queimada Grande Island in Brazil, where it is critically endangered.

11-Mar-2026
The complete #genome of the #goldenLancehead reveals how genes responsible for #venom #toxins evolved

https://www.eurekalert.org/news-releases/1119646 #science #snakes #ecology #evolution #snakeVenom

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Researchers develop new way to safely insert gene-sized DNA into the genome Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient’s cells. However, most genetic disorders are caused by dozens or even thousands of unique mutations spread across a gene; this diversity results in challenges of scale when it comes to developing customized therapies for many individuals. A more universal strategy could involve the precise insertion of an entire copy of a healthy gene into a specific location in the genome, which could, in principle, provide a single, widely applicable treatment for all patients irrespective of their mutation within that gene.   Taking a step towards developing genetic therapies at scale, researchers from Mass General Brigham and colleagues describe a novel, non-toxic approach for inserting gene-sized DNA in a study published in Nature.

11-Mar-2026
Researchers develop new way to safely insert #gene-sized #DNA into the #genome

https://www.eurekalert.org/news-releases/1119454 #science #geneTherapy

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From the genome to super-pangenome: a new paradigm for accelerated crop improvement - npj Science of Plants npj Science of Plants - From the genome to super-pangenome: a new paradigm for accelerated crop improvement

From the #genome to #super-pangenome: a new paradigm for accelerated #crop improvement

www.nature.com/articles/s44...

#PlantScience #SciComm @natureportfolio.nature.com @natrevgenet.nature.com @pangenomics.bsky.social @plantgenomes.bsky.social @plantgenomics.bsky.social @ahalllab.bsky.social

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GBE | Comparative Genomics and Phylogenomics of the Mustelinae Lineage (Mustelidae, Carnivora)

GBE | Comparative Genomics and Phylogenomics of the Mustelinae Lineage (Mustelidae, Carnivora)

Totikov et al. present a comparative and phylogenomic study of the Mustelinae, uncovering striking variation in genome-wide heterozygosity and genome size, marked homozygosity in some Asian lineages, and remarkable diversity in widespread species.

🔗 doi.org/10.1093/gbe/evag014

#genome #evolution

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GBE | Genomics of Sable (Martes zibellina) × Pine Marten (Martes martes) Hybridization

GBE | Genomics of Sable (Martes zibellina) × Pine Marten (Martes martes) Hybridization

Tomarovsky et al. resequenced sable, pine marten, and hybrids of these two mustelids, finding a broad spectrum of hybrid types with mosaic recombinant chromosomes that confirm hybrid fertility and indicate crossover is not suppressed.

🔗 doi.org/10.1093/gbe/evag018

#genome #evolution

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Breakthrough Research: This Electrolyte IS CAUSING Chronic Fatigue & Long Covid
Breakthrough Research: This Electrolyte IS CAUSING Chronic Fatigue & Long Covid YouTube video by Felix Harder

#LongCOVID?
#ATP #potassium
#calcium #sodium
✅ Independent Replication: #Mitochondria contain their own #genome & can replicate independently of the cell's nucleus
✅ Energy-Demand Driven: Mitochondria multiply with increased cell's energy needs, such as in muscle cells that are frequently stimulated

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IZFS Webinars | IZFS - International Zebrafish Society About | Upcoming Webinars | Previous Webinars | Sponsors | Sponsorship Opportunities

One week until the IZFS Webinar! Join us on 3/19 at 10 AM EDT for From Code to Coat: The 'complete' zebrafish genome and the developing epidermis. Register now at www.izfs.org/education/webinars

#IZFSWebinar2026 #Genome #ZebrafishResearch #DevelopingEpidermis

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GBE | A Chromosome-level Assembly and Functional Genomic Resources for the Model Annelid Capitella teleta

GBE | A Chromosome-level Assembly and Functional Genomic Resources for the Model Annelid Capitella teleta

Davies et al. assemble the genome of polychaete Capitella teleta, a model for evolutionary developmental biology, comparative genomics, conservation, and ecotoxicology, generating a 243 Mb chromosome-level genome, and publish a genome browser.

🔗 doi.org/10.1093/gbe/evag041

#genome #evolution

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👀 The bot is not wrong #Brassica #plant #genome #evolution #polyploidy #academicsky

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A family‐level phylogeny of liverworts (Marchantiophyta): New insights from mitochondrial sequences This study reconstructs the evolutionary history of liverworts using mitochondrial genome data. By analyzing phylogenetic relationships, our findings provide new insights into the origin of liverwort...

🚨Liverwort lovers...Don't miss this!
🧬Huang et al. reconstruct the evolutionary history of #liverworts using mitochondrial #genome data, providing insights into their origin AND shedding light on early land #plant #evolution!
🔗 doi.org/10.1111/jse....
@wileyecology.bsky.social
#nonseed #PlantSci

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Cas-SF01 (Cas12i3) in #oilseedrape

TTN PAM: 47% #genome vs. SpCas9 NGG: 16% → 3× wider range

→ Long deletions (>10bp) for complete KO
→ T0: 27.8% homozygous (BnOPR3, BnCLV3)
→ CBE: 13-19% C→T, no off-target

Bnclv3: multi-locule siliques ✓

onlinelibrary.wiley.com/doi/10.1111/...

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GBE | Evolution of Highly Repetitive Silk Genes in the Luna Moth, Actias luna

GBE | Evolution of Highly Repetitive Silk Genes in the Luna Moth, Actias luna

Foquet, @kkbugtime.bsky.social @paulbfrandsen.bsky.social @akitokawahara.bsky.social et al. chracterized silk genes in the Luna moth, finding that sericin gene duplications enable dynamic shifts in silk composition within and between species.

🔗 doi.org/10.1093/gbe/evag036

#genome #evolution

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📢 A new episode is out!

Brenda and Jason speak with Dr. Daniel Peeper (@peeperlab.bsky.social) at the Netherlands Cancer Institute about the use of function-based, #genome-wide screens to develop concepts for rational combinatorial #cancer treatment.

🎧 Listen now: https://bit.ly/3OVwMo6

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Long-Read Genome Sequencing Uncovers New Autism Gene Variants By utilizing long-read sequencing, an emerging technique that reads large sections of the genome at once, scientists at UC San Diego have revealed new genetic variants associated with autism spectrum ...

Researchers @sebatlab.bsky.social utilized long-read whole #genome sequencing and identified new #genetic variants associated with Autism. This enhanced the discovery of variants, leading to the potential for accurate testing and new therapies.
#AutismSpectrumDisorder
today.ucsd.edu/story/long-r...

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From #seed to whole #plant: An innovative visual marker system to enhance selection efficiency in #soybean #genome editing
☀️🌈🌱https://doi.org/10.1016/j.jia.2025.06.010
Researchers at Jilin Academy of Agricultural Sciences & WIMI Biotechnology
#MolecularBiology #GeneEditing

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Recurrent Chromosome Destabilization Through Repeat-Mediated Rearrangements in a Fungal Pathogen Abstract. Genomic instability caused by chromosomal rearrangements has severe consequences for organismal fitness and progression of cancerous cell lines.

Fouché, @oggenfussursula.bsky.social, McDonald & @danielcroll.bsky.social retrace chromosomal degeneration in a fungal pathogen, identifying the exact sequence triggers that initiate chromosome instability and perpetuate degenerative cycles.

🔗 doi.org/10.1093/gbe/evag037

#genome #evolution

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Assessing the Potential of Ancient Protein Sequences in the Study of Hominid Evolution Abstract. Palaeoproteomic data can provide invaluable insights into hominid evolution over long timescales. Yet, the potential and limitations of ancient p

@ipatramanis.bsky.social @lauritsskov.bsky.social Cappellini & Racimo show that phylogenetic inferences based on ancient protein sequence data may sometimes differ from DNA-based inference.

🔗 doi.org/10.1093/gbe/evag035

#genome #evolution #humanevolution

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Clinical risk factors like low birthweight, prematurity, and prolonged NICU stay can help identify infants most likely to benefit from genetic testing, streamlining diagnosis and care. bit.ly/40ieK1U #GIMO #NICU #Genome #GeneticTesting #RiskFactors #CriticalIllness

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NEW IZFS Webinar! From Code to Coat: The 'complete' zebrafish genome and the developing epidermis. Join Shawn M. Burgess (@burgesslab.bsky.social) and Mahendra Sonawane at 10:00 am EDT on March 19th! Register today at www.izfs.org/education/webinars #IZFSWebinar2026 #Genome #ZebrafishResearch

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Decoding the Avian Missing Gene Mystery: Dot Chromosomes Unmask Extensive Gene Loss and Novel Genetic Instability Abstract. The apparent absence of numerous conserved vertebrate genes from avian genomes has puzzled researchers for over a decade. In recent years, a subs

Hron, @dalibormiklik.bsky.social @hpaces.bsky.social et al. demonstrate that avian dot microchromosomes harbor widespread gene attrition; retained dot chromosomes genes exhibit a new form of dynamic genetic instability - sequence stuttering.

🔗 doi.org/10.1093/gbe/evag038

#genome #evolution #birds

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Predictors of Protein Evolution in the drosophilid Immune System Abstract. The evolutionary dynamics of immune genes are shaped by diverse selective pressures, yet the relative roles of gene-level traits, functional spec

@pankajd.bsky.social & @darrenobbard.bsky.social show that immune genes overall evolve faster at the protein level, but are less prone to copy-number changes than other genes in Drosophila.

🔗 doi.org/10.1093/gbe/evag034

#genome #evolution #drosophila

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Enlightening article review by Buell:

‘Hybrid potatoes: Rooting for heterosis’

tinyurl.com/jesfhwk2

#WIS

#PlantandEnvironmentalScience

#Homozygous

#Heterozygous

#Potato

#Rice

#Maize

#Solanaceae

#IncreasedVigour

#AgriculturalProductivity

#Genome

#Progeny

#GeneticLoad

C. Robin Buell:

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Enlightening article review by Buell:

‘Hybrid potatoes: Rooting for heterosis’

tinyurl.com/jesfhwk2

#WIS

#PlantandEnvironmentalScience

#Homozygous

#Heterozygous

#Potato

#Rice

#Maize

#Solanaceae

#IncreasedVigour

#AgriculturalProductivity

#Genome

#Progeny

#GeneticLoad

Fig.1

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Happy #InternationalWomensDay! 💙

Celebrating the women driving progress, safety, and innovation in #healthcare. At #Genome, their expertise turns data into action, strengthens #PatientCare, and helps build a safer, more equitable future for patients and staff.

#IWD2026 #GiveToGain

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Identical twins on trial: can DNA testing tell them apart? In a French criminal trial, conventional DNA analysis couldn’t distinguish between twin brothers, but emerging scientific methods could help in such cases.

Distinguishing #monozygotic #twins in a criminal trial: when conventional #DNA analysis is not enough
👉 whole #genome sequencing
👉 #mitochondrial DNA sequencing
👉 DNA #methylation analysis
www.nature.com/articles/d41...

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Molecular Complexity Constrained Early Amino Acid Recruitment into the Genetic Code Abstract. Previously proposed chronologies of amino acid incorporation into the genetic code rely on consensus rankings derived from prebiotic synthesis ex

Hashmi et al. reconstructed a complexity-based amino acid chronology, integrating 16 molecular complexity metrics, suggesting that molecular complexity constraints influenced substitution patterns during genetic code evolution.

🔗 doi.org/10.1093/gbe/evag012

#genome #evolution

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The #ERGA committees cover every step of the #genome generation pipeline, from sampling to communicating research results. They are #open to all members who wish to get involved:
www.erga-biodiversity.eu/community-co...

➡️ Choose your favorite, email them, and join today!

@ebpgenome.bsky.social

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With Evo 2, AI can model and design the genetic code for all domains of life
www.eurekalert.org
#dna #gentics #biotech #genome #stem #life #humanity #medical #futurehumans

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GBE | Recent Microbial Evolutionary Insights From Metagenomics

GBE | Recent Microbial Evolutionary Insights From Metagenomics

Moguel et al. publish a new Review on how metagenomics has revolutionized our understanding of microbial evolution, revealing lineages and functional adaptations, and reshaping our view of the Tree of Life.

🔗 doi.org/10.1093/gbe/evag029

🖌️ Laura Carrillo Olivas

#genome #evolution #microbesky

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