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Sometimes the giant cells in granulomatous inflammation are truly giant!

#nephsky #pathsky #renal #kidneypath

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A sample from the pathology teaching slide set on Lupus Nephritis and Thrombotic Microangiopathy (TMA), jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/

#KDIGO #pathology #renal #kidneypath

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Here is today’s #eyeSCANdy! Scanning EM of a normal glomerulus showing a glomerular capillary loop with interdigitating podocyte foot processes. 

Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

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There were also mesangial IgA deposits (Figure 3), which likely explain the patient's hematuria and proteinuria, since there was very little glomerular amyloid (Figure 4).

#renalpath #kidneypath #pathology #renal #pathsky

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The stain is a Congo Red viewed under fluorescent light with a red filter. It highlights interstitial amyloid deposits, which is the predominant pattern of deposition in LECT2 amyloidosis (confirmed by IHC stain, Figure 2).

#renalpath #kidneypath #pathology #renal #pathsky

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1/ This allograft biopsy shows the characteristic features of adenovirus infection.  

#TeachingPoints #kidneypath #renal #pathology

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This is the biopsy of a 62yo Hispanic female with hematuria and proteinuria. What is this stain and what is the diagnosis?

#DiagnoseThis #nephtwitter #pathtwitter #renal #kidneypath

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A sample from the pathology teaching slide set on Lupus Nephritis: Maintenance Therapy for Class Ill and IV LN, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/

#KDIGO #pathology #renal #kidneypath

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Here is today’s #eyeSCANdy! Scanning EM of a normal glomerulus showing a glomerular capillary loop with interdigitating podocyte foot processes.

Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

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1/ This electron microscopy shows marked GBM abnormalities, consistent with Alport's Syndrome (AS). The patient had genetic testing, which confirmed a COL4A3 mutation.

#renalpath #kidneypath #pathology #renal

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2/ Predominantly subepithelial deposits, in contrast, would be expected in most cases of membranous glomerulopathy.  

#TeachingPoints #kidneypath #renal #pathology

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In a 23yo M with proteinuria, hematuria and CKD, what is your diagnosis?

#DiagnoseThis #nephsky #pathsky #renal #kidneypath

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Here is today’s #eyeSCANdy! Acellular scanning EM of a normal glomerular tuft showing the subpodcocytic capillary loop basement membranes following removal of the podocytes. 

Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

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A sample from the pathology teaching slide set on Immunoglobulin and Complement-Mediated Glomerular Diseases with an MPGN Pattern of Injury, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/

#KDIGO #pathology #renal #kidneypath

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1/ The biopsy shows collapsing glomerulopathy, for which the differential diagnosis in a transplant recipient includes ischemia, calcineurin inhibitor nephrotoxicity, CMV infection, thrombotic microangiopathy, and donor-derived APOL1-associated nephropathy.

#renalpath #kidneypath

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This is the biopsy from a 41yo Middle Eastern female who received a renal transplant a few years prior and presents with AKI. What is your diagnosis? 

#DiagnoseThis #nephsky #pathsky #renal #kidneypath

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Here is today’s #eyeSCANdy! Acellular scanning EM of a normal glomerular tuft showing the subpodcocytic capillary loop basement membranes following removal of the podocytes. 

Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

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A sample from the pathology teaching slide set on Immunoglobulin and Complement-mediated Glomerular Diseases with an MPGN Pattern of Injury, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/

#KDIGO #pathology #renal #kidneypath

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In a renal transplant recipient, what is your diagnosis?

#DiagnoseThis #nephsky #pathsky #renal #kidneypath

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Oxalate Nephropathy & Renal Embolic Disease Collision Case | Collidescope Episode 10
Oxalate Nephropathy & Renal Embolic Disease Collision Case | Collidescope Episode 10 Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

What happens when oxalate nephropathy & renal embolic disease interact? How does this interaction impact kidney function? Find out the answer in our latest #Collidescope episode!

#renalpath #kidneypath #pathsky #renalsky

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Here is today’s #eyeSCANdy! Collecting duct showing ostia of an entering distal tubule.  

Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

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Oxalate Nephropathy & Renal Embolic Disease Collision Case | Collidescope Episode 10
Oxalate Nephropathy & Renal Embolic Disease Collision Case | Collidescope Episode 10 Nyd de videoer og den musik, du holder af, upload originalt indhold, og del det hele med venner, familie og verden på YouTube.

In this week's #Collidescope case, Dr. Charles investigates a case of oxalate nephropathy & renal embolic disease. Watch the episode to learn more about how these two diseases interact and affect kidney function. 

#renalpath #kidneypath #pathsky #renalsky

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Nephrocalcinosis secondary to a parathyroid adenoma

doi.org/10.1016/j.kint.2025.07.030

#NephSky #MedSky #AKI #kidneybiopsy #renalpath #kidneypath

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Oxalate Nephropathy & Renal Embolic Disease Collision Case | Collidescope Episode 10
Oxalate Nephropathy & Renal Embolic Disease Collision Case | Collidescope Episode 10 Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

What happens when oxalate nephropathy & renal embolic disease interact? How does this interaction impact kidney function? Find out the answer in our latest #Collidescope episode!

#renalpath #kidneypath #pathsky #renalsky

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A sample from the pathology teaching slide set on Immunoglobulin- and Complement-mediated Glomerular Diseases with an MPGN Pattern of Injury, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/

#KDIGO #pathology #renal #kidneypath

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Oxalate & Renal Embolic Disease Collision Case | Collidescope Episode 10
Oxalate & Renal Embolic Disease Collision Case | Collidescope Episode 10 Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

Dr. Charles is back with another #Collidescope case! Learn about how oxalate & renal embolic disease interact and affect kidney function! #renalpath #kidneypath #pathsky #renalsky

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The biopsy shows linear IgG staining along the GBM, and extensive fibrinogen staining within the Bowman space, consistent with crescent formation. These findings are diagnostic of anti-GBM disease.

#renalpath #kidneypath #pathology #renal

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The differential diagnosis for interstitial hemorrhage includes hemorrhagic necrosis in the setting of renal artery thrombosis, infection (e.g. herpes simplex virus, adenovirus, hantavirus, Rickettsia),...(1/2)

#TeachingPoints #kidneypath #renal #pathology

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In a patient with AKI and hematuria, what is your diagnosis?

#DiagnoseThis #nephsky #pathsky #renal #kidneypath

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(1/2) A case of florid ALECT2 type amyloidosis. This is a Hispanic patient who had not seen a physician in several years. Leukocyte chemotactic factor 2 type amyloidosis (ALECT2) is a form of amyloid of unknown etiology.  #renal #pathtwitter #kidneypath #underthescope

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