Erin Aboelnour, Ph.D.

LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development Long interspersed nuclear element 1 (L1) retrotransposons represent a vast source of divergent genetic information. However, mechanistic analysis of whether and how L1s contribute to human development...

New preprint from our lab. Led by the outstanding @anitaada.bsky.social and @raquelgarza.bsky.social. Funded by @asapresearch.bsky.social and @vetenskapsradet.bsky.social.

LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development

www.biorxiv.org/content/10.1...

Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function - Nature Communications Remyelination can restore neural function. Here, the authors characterize the drivers and limits of endogenous remyelination and explore a therapy that rescued remyelination deficits and accelerated n...

New paper out from the lab! Led by @gdfnunes.bsky.social and Lindsay Osso in collaboration with the lab of Dan Denman. Check it out! 🔬 🐭 🧠

www.nature.com/articles/s41...

The protein kinase C modulator bryostatin-1 therapeutically targets microglia to attenuate neuroinflammation and promote remyelination Protein kinase C modulation with bryostatin-1 enables innate immune cells in the central nervous system to promote myelin repair and regeneration.

Excited to share our new work identifying PKC as a druggable target for modulating microglia in order to enhance myelin repair. 🧵 #remyelination #multiplesclerosis www.science.org/doi/10.1126/...

Modeling the acutely injured brain environment in vitro. https://www.biorxiv.org/content/10.1101/2025.01.08.631921v1

Molecular and cellular dynamics of the developing human neocortex - Nature Tripotential intermediate progenitor cells are responsible for the local production of GABAergic neurons, oligodendrocyte precursor cells and astrocytes in the human neocortex.

Excellent work by @liwangneuro.bsky.social
Arnold Kriegstein and colleagues, deepening our understanding of the molecular and cellular dynamics of the developing human neocortex. The identification of a tripotential intermediate progenitor subtype is a key finding 🧪🧠🧬
www.nature.com/articles/s41...

MS brain atlas could pave the way for personalised treatment An international research team, including researchers at Karolinska Institutet, has mapped the genes expressed in the brain cells of people with multiple sclerosis (MS). The atlas, which is presented ...

news.ki.se/ms-brain-atl...

@annawilliamslab.bsky.social
@willmacnair.bsky.social
@deckardw.bsky.social
@karolinskainst.bsky.social
@edinburghuni.bsky.social
@cp-neuron.bsky.social
and many others....

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing Nature - A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects associated with T...

Thrilled to see this paper out!! 🧪

Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors!

Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social!

rdcu.be/d33uQ 🧵

3 reviews on planning, execution, & validation of transcriptomic experiments in neuroscience published in @natureportfolio.bsky.social #NatureNeuroscience.
A MUST READ if you're doing transcriptomics.
3 reviews, an amazing editorial, a beautiful cover – this is the issue of the year!
(mini thread)

The December issue of Nature Neuroscience is now live, featuring our Focus on Single-Cell Genomics! We hope that these consensus reviews from experts in the field will serve as a useful guide for neuroscientists regarding best practices for these approaches.

www.nature.com/neuro/volume...

‘A place of joy’: why scientists are joining the rush to Bluesky Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.: https://www.nature.com/articles/d41586-024-03784-6

There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.

A Place of Joy.

Hi Ethan, Thank you so much for helping our niche connect! Please include me, a new postdoc joining the glia field and excited to connect with new colleagues!

Oligodendroglia starter pack!

Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!

go.bsky.app/JgL2evN

There’s still time to register for the first-time reviewers workshop with @reviewerzero.bsky.social!

Geared toward people in the 🧠 sciences but useful and open to all ✨

Register 👇🏽 blackinneuro47.wildapricot.org/event-5883989

#Neuroskyence #Blackademics #PhDSky #AcademicSky #BlackInSTEM 🧪