Charlotta Böiers, MD, PhD

Chromatin Accessibility Shapes Developmental-Specific Lineage Plasticity in Hematopoiesis Cell differentiation is governed by dynamic changes in chromatin accessibility, and its dysregulation underlies multiple disease states. Prior to birth, development of the hematopoietic system constit...

Don’t miss our new preprint!
We mapped chromatin accessibility in human first-trimester HSPCs, revealing key fetal vs adult differences in hematopoiesis.
🔗 doi.org/10.64898/202...
#Hematopoiesis #StemCells #Chromatin #Epigenetics #LeukemiaResearch

Resolving the prenatal events of KMT2A::AFF1-driven disease initiation We here provide key insights into the KMT2A::AFF1 pre-leukemic phase using a novel murine model, of critical importance to human disease initiation.

Don´t miss our blog post highlighting our latest paper in Leukemia.

go.nature.com/4ltklea

Don't wait for the first scientific session to start your networking and learning at #ISEH2025 🏯 . Kick off your meeting experience with pre-meeting workshops and networking opportunities on 24 September. Add these on to your registration ➡️ www.iseh.org/2025Workshops

Three researchers receive Barncancerfonden funding to investigate the causes of childhood leukemia Lund University. This spring Barncancerfonden, the Swedish Childhood Cancer Foundation, awarded SEK 64 million to 29 researchers across the country. The funding includes positions of up to six years f...

Congratulations to everyone!
It’s incredibly exciting to see our lab getting recognition with the postdoc grant to Keiki.

www.stemcellcenter.lu.se/article/thre...

Three researchers receive Barncancerfonden funding to investigate the causes of childhood leukemia Lund University. This spring Barncancerfonden, the Swedish Childhood Cancer Foundation, awarded SEK 64 million to 29 researchers across the country. The funding includes positions of up to six years f...

🎗️What causes childhood leukemia to develop?

With funding from Barncancerfonden, 3 early-career researchers at Lund Stem Cell Center are investigating the origins & progression of the disease.

Read more in our full Q&A:
www.stemcellcenter.lu.se/article/thre...

#ChildhoodCancer #LeukemiaResearch

We report a murine KMT2A::AFF1 model with a unique pre-leukemic state confined to the embryo and marked by CD24. The expanded subset has pre-leukemic stem cell features, that can be linked to human disease, laying the foundation to target disease onset.

Ontogeny-specific induction of the KMT2A::AFF1-fusion drives development of a distinct CD24 positive pre-leukemic state - Leukemia Leukemia - Ontogeny-specific induction of the KMT2A::AFF1-fusion drives development of a distinct CD24 positive pre-leukemic state

Thrilled to share our latest research just published in Leukemia. www.nature.com/articles/s41...
Grateful to all co-authors for their dedicated effort and collaboration. @lundstem.bsky.social @lunduniversity.bsky.social

So nice to attend the European Hematology Association (EHA) Annual Meeting in very warm but beautiful Milano! A real pleasure to see our lab’s latest research presented — always inspiring to watch science move forward.
#EHA2025 #Research #Hematology

Read the latest highlights on articles in the #ExpHem May Issue and Special Issue on Bone Marrow Aging www.simplyblood.org

Lab Spotlight: Tremblay Lab Tremblay Lab Each month, Simply Blood spotlights a lab contributing to the fields of hematology, immunology, stem cell research, cell and ge...

Don´t miss the Lab Spotlight of Tremblay Lab on #SimplyBlood. Read about their latest projects and accomplishments on simplyblood.org.

This month on #SimplyBlood🩸we're featuring the Tremblay Lab @cedricstremblay.bsky.social based out of the University of Manitoba, Canada. Read about their latest projects and accomplishments on www.simplyblood.org

This week on #SimplyBlood 🩸 we're highlighting articles in the ExpHem Special Issue: New Culture Methods in Experimental Hematology from guest editor @krikirschner.bsky.social Read the highlights on www.simplyblood.org.

Outstanding contributions to our field and society acknowledged with this year’s ISEH awards. Presentations and award seminars at this year’s annual meeting in Kumamoto iseh.org/page/iseh2025

Amazing collection of reviews on developmental hematopoiesis from leaders in the field. Just out in @iseh.bsky.social journal, Experimental Hematology www.exphem.org/content/edit...

For 10 years #UniStemDay has brought 1000s of students to Lund University for a hands-on look at science. This year 200+ students explored stem cells, regenerative medicine & more—guided by our researchers, sparking curiosity & inspiring the next generation!

Explore the #UniStemDay2025 highlights ⤵️

This week on #SimplyBlood 🩸 the New Investigators Committee explores alternative career opportunities beyond academic science. If you're curious about a career transition or want to explore alternative paths beyond academia, read more on www.simplyblood.org

ISEH Highlights Women in Science On March 8th every year, the achievements of women are celebrated worldwide in conjunction with International Women's Day. It highlights the...

Today is International Women's Day. Don´t miss ISEH highlights women in science on Simply Blood: www.simplyblood.org/2025/03/iseh...

2025 Board of Directors Election - International Society for Experimental Hematology

@isehsociety.bsky.social members: Vote for the next generation of society leadership here www.iseh.org/page/2025Ele... Absolutely outstanding slate of nominees

ISEH interviewed our 2024 Award Winner for Leadership in DEI, Dr. Katherine King. Check out the interview in our latest #SimplyBlood🩸 blog post to hear tips and activities to build an inclusive lab environment and more! simplyblood.org

There’s still time to submit an abstract! Join us for what promises to be a great online symposium for all interested in hematology research! And you might win a travel grant for the 2025 Annual ISEH meeting in Japan… what more do you need 🤷‍♂️