I’ve been having some really fun experiences with LLMs over the past year learning how to do things in software that I never thought I’d be able to learn. It’s not perfect, but I have been able to meaningfully create a workflow for my data (from acquistion to archiving) that I’ve always dreamed of
Is the answer to everything not to only buy as much SLC flash as possible forever?
We are losing scientists from the government at an unprecedented rate - some were fired, but many more were forced out through trauma and fear. www.science.org/content/arti...
Zarr is great and so are you
@zarr.dev is literally the coolest
Excited to share our newest project using spatial transcriptomics with novel image analysis approaches to investigate the impact of biological risk factors for Alzheimer's disease (AD) - APOE haplotype, sex, and genomic ancestry - on molecular states in the locus coeruleus (LC 🔵) of the human 🧠.
“It’s hard to know if I should close down my existing projects and/or redouble my efforts writing new grant applications,” Joshua Jacobs, associate professor of biomedical engineering at Columbia University, told @thetransmitter.bsky.social.
By Natalia Mesa
www.thetransmitter.org/funding/nih-...
Brain as a computer arguments in shambles. Brain as toilet arguments reign.
cc @mishaahrens.bsky.social !
Woohoo! Go Ginny!
Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing.
www.biorxiv.org/content/10.1...
Here's what this means: it's probably unlawful forPOTUS to stop NIH funds from going to medical research, but POTUS can stop that medical research for a lengthy period of time while the Court of Federal Claims hears lawsuits
This, essentially, destroys the capacity for medical research in the US
The ideological cancellation of $800 million of scientific research grants because they supposedly focused on DEI was just backed by the Supreme Court. This is horrific on so many levels.
VAST is pretty neat, I’m excited to see what you accomplish with them!
Yes! Sharing neural recordings improves reproducibility and transparency, and reduces the need for new experiments - we should value it. And reuse is really happening: @steinmetzneuro.bsky.social's datasets (highlighted) have over 80k downloads! 🔥 figshare.com/authors/Nick...
Reminder that we still have time to fight this! This bill is being crafted & debated in the coming days and weeks. Organize NOW to do outreach and get people in your neighborhood contacting their reps. @standupforscience.bsky.social has resources. Instructions for Postcards-for-Science are here:
A puget systems computer and monitors on a moving cart. A green dinosaur called Rexy from the AO Racing Team sits on top to help.
Moving my awesome @pugetsystems.com machine with the help of the legendary @aoracingusa.bsky.social Rexy. Gonna be the fastest (and safest) move ever
tl;dr — this EO co-opts the language of open science to implement a system of political control wherein presidential appointees are given broad latitude to designate any number of reasonable scientific activities and inferences as scientific misconduct, and to penalize those involved accordingly.
1. It's Fustilarian Friday and today's drop is the "Restoring Gold Standard Science" executive order.
My read is that this is designed to (1) protect far-fringe figures such as the antvaxxers now heading our health agencies, and (2) kneecap efforts to use scientific evidence in regulatory policy.
🧪 Federal science funding cuts directly threaten public services. Reduced operations at NOAA, CDC, and EPA mean compromised weather forecasts, disease surveillance, and environmental safeguards.
HHMI has paused consideration for a new round of its Hanna Gray postdoc fellowship
Applicants feel it's the latest step in the academic pipeline contracting 🧪
www.statnews.com/2025/05/19/h...
Table: Top 10 funding programs of new grant terminations Funding Opportunity Numbers,Program Title,Terminated Grants,Grants Value PA-23-189, PA-21-071, PA-20-222,Research Supplements to Promote Diversity in Health-Related Research,191,$768,214,323 PA-20-185, PA-19-056, PA-20-184, PA-20-183,Research Project Grant,109,$290,364,678 PA-21-049, PA-20-251, PA-23-271, PA-21-052,Ruth L. Kirschstein National Research Service Award,76,$5,232,698 PAR-19-218, PAR-21-146,Undergraduate Research Training Initiative for Student Enhancement,58,$45,889,490 PAR-24-031, PAR-19-037, PAR-21-025,Initiative for Maximizing Student Development,38,$43,152,674 PAR-22-220, PAR-20-066,Postbaccalaureate Research Education Program,29,$97,054,509 PAR-21-271, PAR-21-272, PAR-19-343,Maximizing Opportunities for Scientific and Academic Independent Careers,22,$5,529,685 PAR-22-241,NIAID Research Opportunities for New and "At-Risk" Investigators to Promote Workforce Diversity,21,$21,601,155 PAR-21-313,Small Grants for New Investigators to Promote Diversity in Health-Related Research,18,$7,200,840 PAR-23-114, PAR-20-223,Enhancing Science, Technology, EnginEering, and Math Educational Diversity,12,$6,550,142
🚨 Over 700 previously undisclosed #NIH grant terminations were released this week, totaling $1.7B and nearly doubling our count of terminations to >1500.
Diversity supplements for research awards are a huge fraction, as well as service awards and training programs.
grant-watch.us/posts/700-ne...
It is pretty cool. The more I use some of this stuff the more I think it’s a miracle anything works at all.
I have learned that graphics programming is literally a miracle and I don’t understand how the hell people do this for a living. Just getting displays to refresh at appropriate time points if they aren’t at the same frame rate was so hard man.
NEW: Whistleblower records show that the NIH axed research grants – even after a federal judge blocked the cuts with an injunction.
www.propublica.org/article/trum...
🧵
The bill, which was approved today by the U.S. House of Representatives and heads next to a Senate vote, includes 20 percent less BRAIN Initiative funding than last year.
By @avaskham.bsky.social
www.thetransmitter.org/funding/u-s-...
It's hard to say this, but science (& research more generally) is just being **stopped** in the US right now. This is just one university, losing nearly a billion dollars in project funding pretty much overnight. That's people's jobs & the research that could save lives.
www.wsj.com/health/healt...
"The Trump administration has terminated $800 million in grants to Johns Hopkins University, spurring the nation’s top spender on research and development to plan layoffs and cancel health projects, from breast-feeding support efforts in Baltimore to mosquito-net programs in Mozambique."
