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HBio ISP

@hbio-isp

A @johninnescentre.bsky.social research programme to harness the remarkable biosynthetic capabilities of plants and microbes.

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16.01.2025
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Latest posts by HBio ISP @hbio-isp

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Funding Opportunities - Biofortification Hub Funding Opportunities The Biofortification Hub offers funding to support innovative research, collaboration, events and mobility between Academia and Industry. Type of funding

Funding opportunities for the Biofortification Hub are open for 2026 πŸŒ±πŸ…

Those working in #Biofortification in the UK in industry, organisations or academia can apply for:

β€’ Proof of Concept Awards
β€’ Business Interaction Vouchers

πŸ—“οΈ Deadline: 24 April 2026

@quadraminstitute.bsky.social

09.02.2026 23:02 πŸ‘ 4 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Sugar beet, oilseed rape, tomatoes and dandelions: four precision breeding projects win major funding to support UK agriculture | John Innes Centre The John Innes Centre and its industrial and academic partners have been awarded UK Government funding to help deliver four ambitious projects that unleash the potential of precision breeding…

🌱 Since the Precision Breeding Act, the UK Government has awarded funding for many interesting projects using #GenomeEditing, important for farmers and sustainable agriculture.
πŸ‘‡ Check out the four new projects at the @johninnescentre.bsky.social
www.jic.ac.uk/press-releas...

10.02.2026 15:26 πŸ‘ 10 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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How specific are heritable symbioses?

And what can we learn from swapping obligate symbionts across host species?

We address this in our latest, led by @inespons.bsky.social & in our collaboration w/ @microbiome.bsky.social 🦠πŸͺ² Out today in @natcomms.nature.com!

1/n
www.nature.com/articles/s41...

16.02.2026 07:24 πŸ‘ 115 πŸ” 70 πŸ’¬ 3 πŸ“Œ 3

If anyone is interested in working on these bacteria @johninnescentre.bsky.social has protocols, strains, plasmids and a genome database available here: streptomyces.org.uk

16.02.2026 20:01 πŸ‘ 11 πŸ” 13 πŸ’¬ 0 πŸ“Œ 1
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Here’s a sneak preview of the Microbe Zoo coming to Norwich Science Festival soon πŸ‘€

πŸ“…14 - 21 February 2026
πŸ“The Gallery, the Forum Norwich

➑️ buff.ly/gtZX6Us

@norwichmicro.bsky.social @johninnescentre.bsky.social @thesainsburylab.bsky.social @earlhaminst.bsky.social @uniofeastanglia.bsky.social

12.02.2026 10:02 πŸ‘ 26 πŸ” 17 πŸ’¬ 1 πŸ“Œ 0
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<i>Microbiology</i> Editors: Call for expressions of interest

Want some editorial experience? The @microbiologysociety.org flagship journal Microbiology has opened a call for new editors, more details here:

microbiologysociety.org/news/society...

23.01.2026 13:20 πŸ‘ 7 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0

First results chapter from Kelly-Rose Tulley’s PhD is published. It was a great team effort to get this finished. This work supports previous results on S. coelicolor OrrA and suggests its function is highly conserved. #microsky #streptomyces 1/2

01.02.2026 08:22 πŸ‘ 13 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0

Seed cannot be made available in the UK unfortunately.

29.01.2026 17:03 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

VACANCY - We're looking for a Postdoctoral Researcher to join the @philcarella.bsky.social Group, working in the field of Evo-MPMI (Evolutionary Molecular Plant-Microbe Interactions).

okt.to/yIlgTU

Closing date - 10 February 2026
Salary - Β£37,500 - Β£45,350
Contract - Full-time, 3 years

22.01.2026 13:51 πŸ‘ 6 πŸ” 15 πŸ’¬ 0 πŸ“Œ 0
The Norwich (UK) cathedral spire seen at sunset.

The Norwich (UK) cathedral spire seen at sunset.

New year, new goal of getting enough vitamin D 🌞

1 in 5 people in the UK are deficient in vitamin D during winter and spring πŸ“‰

Get involved in ViTaL-D to investigate whether @johninnescentre.bsky.social biofortified tomatoes lead to more vitamin D in the blood πŸ…

➑️ buff.ly/2sdniq5

24.01.2026 11:00 πŸ‘ 5 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
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EXPERT REACTION: Genetically modified purple tomato approved in Austra EXPERT REACTION: Genetically modified purple tomato approved in Australia A genetically modified purple tomato has received all necessary approvals for commercial sale in Australia, accord

Great news for the Australians!
Purple tomatoes, enriched in beneficial anthocyanins, developed in Cathie Martin's lab @johninnescentre.bsky.social will be available to consumers in Australia in 2026.
www.scimex.org/newsfeed/exp...

28.01.2026 16:07 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
The conserved two-component systems CutRS and CssRS control the protein secretion stress response in Streptomyces

Very happy to see this remarkable work published. Led by @tommclean.bsky.social and @ainsley-beaton.bsky.social. We show how Streptomyces bacteria sense & respond to misfolded secreted proteins. A great collaboration with @barriewilks.bsky.social

#microsky

1/2

journals.asm.org/doi/epub/10....

15.12.2025 14:39 πŸ‘ 25 πŸ” 18 πŸ’¬ 1 πŸ“Œ 0

Too excited by the science to include the link to the paper! Here it is: journals.asm.org/doi/10.1128/...

16.12.2025 04:30 πŸ‘ 13 πŸ” 7 πŸ’¬ 2 πŸ“Œ 0
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Need a winter warmer? Groundbreaking gene-edited tomato soup trial with higher levels of 'Sunshine' vitamin recruiting now - Quadram Institute Human trial of gene edited food, to understand whether biofortifying tomatoes in this way leads to higher levels of vitamin D in the blood

βœ… Are you aged over 18?
βœ… Live within 70 miles of Norwich?
βœ…Think you might be low in vitamin D?

Join the ViTaL-D study and help us understand if @johninnescentre.bsky.social tomatoes biofortified through gene editing could help boost vitamin D levels πŸ…

21.12.2025 16:01 πŸ‘ 7 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
Three volunteers standing behind an outreach stand with microbiology-themed activities on the table

Three volunteers standing behind an outreach stand with microbiology-themed activities on the table

Today we're supporting the Find my Future event at @johninnescentre.bsky.social with hands-on activities that highlight the diversity of micro-organisms.

Thanks to all our volunteers and the event organisers for helping us to engage with lots of students!

27.11.2025 14:20 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Postdoctoral Researcher (Salem Group) | John Innes Centre An exciting opportunity has arisen for a Postdoctoral Researcher to join the newly appointed group of Dr Hassan Salem at the John Innes Centre, working on cutting-edge science in the field of Crop…

VACANCY - We’re looking for a Postdoctoral Researcher to join Dr @hassansalem.bsky.social group, in the field of Crop Genetics.

www.jic.ac.uk/vacancies/po...

Closing date - 15 December 2025
Salary - Β£37,500 - Β£45,350
Contract - Full-time, 17 months in the first instance (potential up to 4 yrs)

03.12.2025 09:48 πŸ‘ 5 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

More broadly the research could also lead to insights into genetic regulation, biotechnology applications, and new strategies for tackling antimicrobial resistance, one of the major threats to human health in the 21st century.

05.12.2025 15:10 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

It also shows that the fold is versatile – not only binding to CTP, but also to other ubiquitous nucleotides including ATP and GTP, including the first examples of GTP-binding ParB-like proteins.

05.12.2025 15:10 πŸ‘ 0 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
The circular tree shows how thousands of ParB-like proteins are distributed and have evolved across bacteria, archaea, phages, and eukaryotes. The coloured rings highlight the origin of each protein and whether it retains key features, such as the canonical ParB structure or the ParA-binding sequence. Long branches reveal fast-evolving, highly diverged versions of the fold, offering a glimpse into how this ancient protein family has diversified across life.

The circular tree shows how thousands of ParB-like proteins are distributed and have evolved across bacteria, archaea, phages, and eukaryotes. The coloured rings highlight the origin of each protein and whether it retains key features, such as the canonical ParB structure or the ParA-binding sequence. Long branches reveal fast-evolving, highly diverged versions of the fold, offering a glimpse into how this ancient protein family has diversified across life.

NEWS - An exciting new landscape of protein-related discovery unfolds

An investigation into cellular components in bacteria has unexpectedly uncovered a feature with relevance across many life forms, paving the way for diverse research and applications:
www.jic.ac.uk/news/an-exci...

05.12.2025 15:10 πŸ‘ 7 πŸ” 3 πŸ’¬ 2 πŸ“Œ 0
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Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation | PNAS Nucleotide triphosphate (NTP)-dependent molecular switches regulate essential cellular processes by cycling between active and inactive states thro...

Now published. Thank you very much to our collaborative team, and very supportive editors and reviewers!!!

www.pnas.org/doi/10.1073/...

04.12.2025 19:22 πŸ‘ 44 πŸ” 12 πŸ’¬ 0 πŸ“Œ 0
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Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation Nucleotide triphosphate (NTP)-dependent molecular switches regulate essential cellular processes by cycling between active and inactive states through nucleotide binding and hydrolysis. These mechanis...

new preprint from our group & Antoine Hocher: www.biorxiv.org/content/10.1...
A fantastic collaboration with Antoine, with Jovana Kaljevic' initiated the collaboration and drives the project.

11.10.2025 11:36 πŸ‘ 67 πŸ” 34 πŸ’¬ 3 πŸ“Œ 3
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Congratulations to Charlotte Owen, winner of our HBio award. For playing a pivotal role in the set-up of spin-out company Hothouse Therapeutics, her exceptional talent in bioinformatics and her many contributions to the running of the Osbourn lab. @johninnescentre.bsky.social

03.12.2025 14:17 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Congratulations to Govind Chandra, winner of our @hbio-isp.bsky.social award. For the critical role he plays in bioinformatics data analysis, supporting colleagues and training new bioinformaticians @johninnescentre.bsky.social

21.11.2025 14:44 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

β€ͺWant to hear about exciting #microbial research from leading scientists? 🦠

The Centre for Microbial Interactions Conference is back next year with an amazing line-up πŸ‘‡

@norwichmicro.bsky.social

13.11.2025 07:20 πŸ‘ 6 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Applied Molecular Microbiology | John Innes Centre John Innes/Rudjer BoΕ‘koviΔ‡ – Summer Schools in Applied Molecular Microbiology Applications are invited for a summer school on Microbial Specialised Metabolites: Discovery…

EVENT - Apply today for the John Innes/Rudjer Boőković: Applied #Molecular #Microbiology Summer School (Microbial Specialised Metabolites: Discovery, Biosynthesis and Function)

πŸ—“οΈ 12 - 20 Sept 2026

πŸ“Inter-University Centre, Dubrovnik, Croatia

Deadline: 23 Jan 2026

www.jic.ac.uk/training-car...

07.11.2025 17:18 πŸ‘ 7 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Why are tomatoes being genetically altered for vitamin D? | BBC News They look and taste like any other tomato, but these tomatoes in Norfolk have been genetically altered to contain more vitamin D. Tomatoes traditionally lack being a good source for vitamin D, but…

πŸ“½οΈBBC News report on our ViTaL-D study now on Youtube

Together with @johninnescentre.bsky.social we're launching one of the first human trials of gene edited food, to understand whether biofortifying tomatoes in this way leads to higher levels of vitamin D in the blood after people have eaten themπŸ…

06.10.2025 10:45 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Rotation biology PhDs | John Innes Centre Prestigious studentships, for entry in October 2022, this multi-disciplinary PhD programme includes; plant science, microbiology, biological chemistry, applied mathematics…

Applications are now OPEN for the JIF Rotation PhD Programme

This prestigious 4-year #PhD programme trains graduate students in Plant and Microbial Sciences at the JIC, @thesainsburylab.bsky.social and @earlhaminst.bsky.social.

πŸ—“οΈ Closing date - 13 November 2025

www.jic.ac.uk/training-car...

08.10.2025 18:47 πŸ‘ 21 πŸ” 27 πŸ’¬ 0 πŸ“Œ 0
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Team JIC are having a cracking time in the β€œFuture of Farm and Agriculture” @farmersweeklyuk.bsky.social zone at New Scientist Live @newscientist.com this weekend 🌟🌾

We’re here on Monday too - come along and see stomata down a microscope and our wonderful wheat varieties!!

@dsw-isp.bsky.social

19.10.2025 15:00 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Professor Cristobal Uauy talking with Professor Sir Ian Chapman, UKRI Chief Executive in front of a CGI of JIC's new glasshouses

Professor Cristobal Uauy talking with Professor Sir Ian Chapman, UKRI Chief Executive in front of a CGI of JIC's new glasshouses

Professor Anne Osbourn FRS talking with Professor Sir Ian Chapman, UKRI Chief Executive in front of Chilean soapbark trees

Professor Anne Osbourn FRS talking with Professor Sir Ian Chapman, UKRI Chief Executive in front of Chilean soapbark trees

Professor Sir Ian Chapman, UKRI Chief Executive in the Germplasm Resources Unit, an example of BBSRC National Bioscience Research Infrastructure, with Simon Orford, Derived Germplasm Specialist

Professor Sir Ian Chapman, UKRI Chief Executive in the Germplasm Resources Unit, an example of BBSRC National Bioscience Research Infrastructure, with Simon Orford, Derived Germplasm Specialist

Professor Sir Ian Chapman, UKRI Chief Executive with Dr Simon Griffiths

Professor Sir Ian Chapman, UKRI Chief Executive with Dr Simon Griffiths

Thank you to Sir Ian Chapman, CEO of @ukri.org, and BBSRC's Dr Jef Grainger and Dr Lee Beniston FRSB for visiting us at Norwich Research Park yesterday, to see how plant and microbial science is supporting healthy plants, healthy people and a healthy planet 🌱🌍

24.10.2025 15:16 πŸ‘ 6 πŸ” 2 πŸ’¬ 2 πŸ“Œ 0
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Botanists unlock the Chilean medical marvel that Charles ... Vaccine properties of the soapbark tree to be cultivated in days rather than years by new process

Recently, we hosted a visit from @jamestapper.bsky.social at @theobserveruk.bsky.social, which included an interview and short tour with Prof. Anne Osbourn who explained the fascinating story of her group's work with the Chilean soapbark tree (Quillaja saponaria) πŸ—žοΈ

observer.co.uk/news/science...

16.09.2025 15:52 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0