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Leighton Pritchard

@widdowquinn

Computational biologist. Views/opinions mine, not my employer's. Repost != agreement. Not green, just pleasant. Fabian. =﹥÷ I can’t see DMs because of the Online Safety Act.

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12.09.2023
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Latest posts by Leighton Pritchard @widdowquinn

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Wait, what now?

12.03.2026 18:14 👍 0 🔁 0 💬 0 📌 0
Map of Iran overlaid across Europe. It's effing huge. Germany, Austria, Poland, the balkkans, loads of Eastern Europe.

Map of Iran overlaid across Europe. It's effing huge. Germany, Austria, Poland, the balkkans, loads of Eastern Europe.

The problem with how we draw maps is that countries near the equator appear 'small'. Iran overlaid on Europe.

Imagine trying to dominate an area this size with just air power or contemplating putting troops in when it's spent forty years preparing to fight exactly the kind of war that results.

12.03.2026 15:07 👍 184 🔁 77 💬 8 📌 3

How can we tap into the enormous functional diversity of microbes on this planet?

Join us at EMBL Heidelberg (8–10 Dec 2026) to learn about ongoing efforts to decode gene function and organisation in human gut microbes, and present your science.

12.03.2026 08:56 👍 22 🔁 22 💬 1 📌 0

We do that as well - the requirement to review our own outputs is what seems unusual.

12.03.2026 12:36 👍 0 🔁 0 💬 1 📌 0
Preview
First 6 Days of Iran War Cost U.S. $11.3 Billion, Pentagon Says

The 2026 National Science Foundation budget is $8.75 Billion.

12.03.2026 04:13 👍 4032 🔁 1875 💬 34 📌 107

We get asked to rate and review our own outputs for REF. This is in addition to being asked to explain in each category why we're proposing the output in the first place - so it's redundant as well as a cheap way to ensure at least one "4*" in the system…

12.03.2026 12:13 👍 0 🔁 0 💬 1 📌 0
Preview
Research Fellow (Postdoctoral) - School of Biosciences - 107071 - Grade 7 This post-doctoral position will contribute to both complementary programmes, developing ‘broadband’ metagenomic sequencing capabilities for rapid detection and characterisation of emerging and unknow...

ARTIC are hiring! Postdoctoral opportunity in metagenomics at the University of Birmingham

edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

12.03.2026 11:20 👍 3 🔁 9 💬 1 📌 2

Pretty sure what's described in this article is against the REF2029 code of practice (e.g. section 13).

Interested to see if there are any teeth to the CoP.

2029.ref.ac.uk/guidance/sec...

12.03.2026 11:43 👍 1 🔁 0 💬 0 📌 0
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Sheffield Hallam restricts TPS access to REF academics only Teaching staff at post-92 institution to be employed by subsidiary firm and lose right to access expensive pensions scheme

Sheffield Hallam’s new plan to save cash:

🔸 All teaching-focused staff to be employed by a subsidiary firm
🔸 All non-REF staff to be moved to a pension scheme with a lower employer contributions

#UKHE

11.03.2026 08:25 👍 5 🔁 6 💬 3 📌 6

When this is all done we should have a tax on everyone who said they had had enough of experts...

12.03.2026 09:04 👍 118 🔁 26 💬 2 📌 0

lmao let’s goooo

12.03.2026 09:35 👍 1580 🔁 237 💬 23 📌 7

Just stumbling around trying to figure out how the world works.

12.03.2026 07:45 👍 2487 🔁 880 💬 115 📌 72

It is quite amusing to me how so many people don’t understand scale .

You would have to have a fleet of around 100k trucks running 24/7 down a road twice the size of the M25

Volumes of oil transitioning this strait are around 20 million barrels a day.

Roughly 70% world trade volume

12.03.2026 08:43 👍 407 🔁 108 💬 69 📌 5

I loved this comparison of the two Menaces.

12.03.2026 09:38 👍 355 🔁 138 💬 13 📌 6

They should put a monkey on the £50 note and a pony on the £10 note to confuse the hell out cockneys.

11.03.2026 19:01 👍 1572 🔁 311 💬 2 📌 8
Image from their link showing evidence of fabricated references

Image from their link showing evidence of fabricated references

Holy smoke. What ultimately happened???

11.03.2026 19:01 👍 201 🔁 76 💬 9 📌 20
Principles of Boogie Management
 
 
Don't blame it on the sunshine
Don't blame it on the moonlight
Don't blame it on the good times 
 
Establish a collaborative working environment
coupled with individual accountability
to prevent a blame culture
from developing in the first place




Brian Bilston

Principles of Boogie Management     Don't blame it on the sunshine Don't blame it on the moonlight Don't blame it on the good times   Establish a collaborative working environment coupled with individual accountability to prevent a blame culture from developing in the first place Brian Bilston

Principles of Boogie Management.

11.03.2026 15:04 👍 383 🔁 110 💬 6 📌 5

How often an appropriate choice of benchmark is absent from a paper announcing a new technique or approach, and it takes papers like this to make the comparisons ;)

11.03.2026 17:41 👍 6 🔁 3 💬 0 📌 0
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Ars Technica: NIH director launches “Scientific Freedom” lectures with non-scientist

by John Timmer @arstechnica.com @jtimmer.bsky.social
Matt Ridley Jay Bhattacharya

bit.ly/4lnUtBH

11.03.2026 16:57 👍 4 🔁 5 💬 0 📌 1
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A single course of antibiotics can have lasting effects on your gut microbiome, with changes that last well beyond 4 years. Three types of antibiotics stood out for their long term disruptive impact (3 at left, Figure)
nature.com/articles/s41...

11.03.2026 17:04 👍 231 🔁 93 💬 11 📌 7

New paper showing that much of the apparent success of protein language models in predicting mutational effects is a mirage: These models mostly memorize sites. 1/
www.biorxiv.org/content/10.6...

11.03.2026 15:18 👍 145 🔁 58 💬 5 📌 3
11.03.2026 17:20 👍 607 🔁 154 💬 49 📌 13
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Obligatory meme.

11.03.2026 15:35 👍 313 🔁 43 💬 5 📌 1
11.03.2026 15:13 👍 165 🔁 44 💬 2 📌 1
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We’re recruiting new Research Group Leaders!
Why join?
🌍Work across EMBL’s 6 sites
🎓Participate in @embl.org courses and seminars
🔬Lead discovery-driven research in a collaborative environment
Apply by 11 April: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ResearchCareers @epetsalaki.bsky.social

11.03.2026 09:21 👍 15 🔁 18 💬 0 📌 0
Home - Pregnant Then Screwed

Just in case anyone else hadn't heard of this group until today:

"we:

> Push for legislative change that creates real equality at home and at work

> Provide free advice and support women to challenge discrimination"

pregnantthenscrewed.com

11.03.2026 14:38 👍 0 🔁 0 💬 0 📌 0

The shoe thing is low on the "important global matters" scale, but HIGH on the "I'll take things a deranged Roman emperor would do for $500, Alex" chart.

11.03.2026 13:42 👍 1993 🔁 333 💬 53 📌 21

jokingly, this is the entire discipline of bioinformatics (again, I kid).

11.03.2026 14:04 👍 14 🔁 4 💬 2 📌 0

"LLMs cope, but scholars would be better served if papers preserved structure and intent for machine consumption."

Oh god, just teach your fucking program how to parse a file like every other person dealing with every other file format.

11.03.2026 13:59 👍 29 🔁 3 💬 3 📌 2

How stupid and ignorant do you have to be to let Ezra Klein do an Issac Chotiner to you?

Watch the video to find out!

11.03.2026 14:07 👍 10 🔁 3 💬 1 📌 0