A couple years ago I never thought that I will hold the FELASA certificate. I started as a synthetic organic chemist, continued in bio-assays and now I am even allowed to work with animals. Looking forward to new tasks and many new things to learn🥳

Happy International Women's Day! 👩‍🔬

To celebrate we're highlighting some of the impactful work published with us in 2024/2025 led by women researchers worldwide. Read our collection👉 pubs.rsc.org/en/journals/articlecollectionlanding?sercode=dt&themeid=05cb992f-f484-49f0-a413-8c7fd2296258

#Chemsky 🧪

Discovery of Phototoxic Metal Complexes with Antibacterial Properties via a Combinatorial Approach | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Vilar and co-workers @InorgChem #iridium #antibacterial #combinatorial #S_aureus #MRSA #phototoxic #ROS #permeability #bactericidal

Congrats @dianamelis.bsky.social for her article in @chemicalscience.rsc.org. We describe the 1st use of bioorthogonal click chemistry with 188Re for radiolabelling of an anti-c-Met VHH Nanobody®. Great collaboration with the Opsomer/Ooms group
@chimieparistechpsl.bsky.social
doi.org/10.1039/D4SC...

Bin leider erst aus dem Urlaub zurück. Viel Spass dort!

Happy I could contribute to this project. Gratulation to Laura who did such a great and most of the work on this!

Toward the Treatment of Glioblastoma Tumors Using Photoactivated Chemotherapy: In Vitro Evaluation of Efficacy and Safety Glioblastoma multiforme (GBM) is highly aggressive, necessitating new therapies. Photoactivated chemotherapy (PACT) offers a promising approach by activating prodrugs with visible light at the tumor site. This study evaluated the anticancer activity of ruthenium-based PACT compounds in U-87MG glioblastoma cells and their safety in SH-SY5Y neuron-like cells. The compound [3](PF6)2 showed promising light-activated anticancer effects in U-87MG cells, while [1](PF6)2 was inactive, and [2](PF6)2 was nonactivated. Interestingly, in SH-SY5Y cells, light-activated [3](PF6)2 increased cell proliferation, similar to donepezil, without causing cell death. Increased Ca2+ uptake was observed, possibly via interaction with the AMPA receptor, as suggested by docking studies. These findings suggest ruthenium-based PACT compounds may serve as potential treatments for GBM, effectively attacking cancer cells while preserving healthy neuronal cells.

My first paper from my time at @unileiden.bsky.social is out🥳 Herein we studied various Ru cages for their safety and potential use against brain tumors. Thanks to my co authors Anja and Matthijs for their amazing work and Sylvestre for his input and the great Teamwork
pubs.acs.org/doi/10.1021/...

Gratulation! I hope you can also enjoy a bit of free and spare time before thr postdoc adventure starts

I also left Twitter due to several reason. Its nice that my feed is now again full of science

Postdoc opportunity at University of Southern Denmark: Has the time come for realizing quantum computing for transition metal complexes?

lnkd.in/dbCJcunq

Deadline: Feb 15, 2025
Start Date: March 1, 2025
Duration: 2 years
More info: kongsted@sdu.dk
RT appreciated 🙏 @chemjobber.bsky.social

Same tradition, different Lab. The this years Chemistree contains byproducts of our synthesis and BODIPY stars on top. The beauty of (Photo)Chemistry in one tree #photochemistry #fluorescence #chemistree

Ben Feringa, Nobel Prize in Chemistry: ‘A single cell is more complex than an entire city’ The Dutch scientist designs the world’s smallest machines, including light-activated drugs to improve treatments for cancer and infection

Urban planners at BlueSky, take notes! 🦋 🏙️ Ben explains why cells are the OG city builders, with more complexity than any metro ever could achieve. Find out about nanomachines, photopharma, the Simpsons and more in the interview made by @elpais.com

english.elpais.com/science-tech...

Bravo for @fabricefrank.bsky.social

In-depth interview. Former biologist turned computer scientist, Fabrice Frank, passionate about science, has since Covid launched into the hunt for scientific fraud. He has revealed several scandals of national magnitude.