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Drugs for Neglected Diseases initiative (DNDi)

@dndi.org

International non-profit developing safe, effective, and affordable treatments for the most neglected patients.

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Latest posts by Drugs for Neglected Diseases initiative (DNDi) @dndi.org

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In 2014, I visited eastern DRC, where @msf.org teams were treating sleeping sickness - the only available treatment was a drug so toxic it killed 1 in 20 patients. In 2026 I'm so proud that, thanks to @dndi.org, patients can be cured with a single dose of a groundbreaking new oral drug, acoziborole.

05.03.2026 10:41 πŸ‘ 6 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1
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Pandemic preparedness: Novo Nordisk Foundation renews its support to DNDi and THSTI to continue the development of broad-spectrum antivirals This grant will enable the continuation of a lead-optimization partnership initiated by DNDi and THSTI in March 2024, building on previous work that demonstrated the promise of this antiviral approach...

@novo-nordisk.bsky.social has renewed its support to DNDi and India’s THSTI to advance the development of a novel broad‑spectrum antiviral candidate targeting influenza and other viruses of pandemic potential, and strengthen pre-clinical research capacity for #pandemic preparedness.
πŸ‘‰ bit.ly/3N6Eo6y

04.03.2026 09:43 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Dr Wilfried remembers treating sleeping sickness patients with the old medicine which was so toxic it killed 1 in 20 patients.

πŸ’Š Acoziborole is a revolution since those dark days: it cures the disease with one-day treatment course & is effective for both stages of the disease. #1Dose1Cure

27.02.2026 14:50 πŸ‘ 14 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1

Thank you @msf.org for your unwavering support reaching this historic milestone for sleeping sickness! 🧑

27.02.2026 14:44 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thank you for sharing this great news for people affected by sleeping sickness! 🧑

27.02.2026 14:37 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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πŸš€ Huge news for people living with #sleepingsickness!

Acoziborole, a one-day, single-dose oral treatment developed with Sanofi, has received a positive opinion from @ema.europa.eu for the treatment of the most common form of sleeping sickness.

πŸ‘‰ bit.ly/46ZFpEi

27.02.2026 11:13 πŸ‘ 21 πŸ” 13 πŸ’¬ 2 πŸ“Œ 9

Neonatal sepsis remains a leading cause of morbidity & mortality worldwide. Clinical trials like NeoSep1 Part 2 are reclaiming the narrative for newborn survival in the Global South.

πŸ‘ Congratulations @gardp.bsky.social & partners for setting a new standard for neonatal healthcare. #AMR

18.02.2026 08:43 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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CEPI launches global plan to secure the future against epidemic and pandemic threats The new five-year strategyβ€”CEPI 3.0β€”was unveiled today as CEPI called on governments, philanthropies and partners to invest US$2.5 billion to strengthen the world’s disease defences.

Today marks the launch of the CEPI 3.0 Investment Case and Strategy.

CEPI 3.0 – our 2027-2031 strategy - is the next step in CEPI’s mission to transform the way the world tackles epidemic and pandemic threats.

Discover more in the press release ⬇️

13.02.2026 09:24 πŸ‘ 7 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1
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Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults Global efforts to eliminate onchocerciasis are hampered by the lack of a macrofilaricidal drug capable of killing adult parasites. Oxfendazole, a veterinary anthelminthic, exhibits macrofilaricidal a...

A Phase I study in healthy African adults assessed oxfendazole, a promising option for filarial diseases such as onchocerciasis. The findings suggest that a five day course of 400 mg daily, or 50 mg twice daily, reaches target exposure with low safety concerns. @PLOSNTDs doi.org/10.1002/psp4...

11.02.2026 15:43 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The future of African public health must be collaborative, data-driven & above all, people-centred.

The recent partnership between @dndi.org & @aphrc.bsky.social will be a gamechanger in strengthening the health ecosystem at large. #HealthEquity
Read moreπŸ”— bit.ly/4tynePW

10.02.2026 17:43 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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We’re at the 16th KEMRI Annual Scientific & Health (KASH) Conference 2026! Visit the DNDi booth to meet our team and learn about our work delivering safe, effective, and affordable treatments for neglected diseases. #KASH2026

11.02.2026 15:30 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Great to see the German NTDs Network bringing parliamentarians together to relaunch the parliamentary working group on neglected tropical diseasesπŸ‘ Thank you to the MPs who have committed to supporting global health and giving visibility to people affected by #NTDs.

09.02.2026 10:11 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Research Roundup: Nipah vaccine development, Single-dose HPV vaccine schedule, African-led research capacity-building In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

Last week, @dndi.org announced a new memorandum of understanding with the African Population and Health Research Center aimed at helping translate African-led research into transformative innovations and health policies.

www.ghtcoalition.org/blog/researc...

05.02.2026 14:30 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Governments play a critical role in ensuring that public investments in health innovation deliver public value. At #EB158, we urged WHO Member States to establish policies on conditions for publicly funded research. Our intervention at @who.int πŸ‘‰ bit.ly/4auqBj2

05.02.2026 16:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Analysis of the consultations on the InfoChagas digital platform Author summary Trypanosoma cruzi infection remains a significant global health challenge, with many individuals at risk facing difficulties accessing essential information and healthcare. To address t...

InfoChagas is an important source of support for people at risk of Chagas disease. This study shows that people in high burden countries use it for guidance on treatment access, transmission risks & referrals, helping reduce major care gaps. doi.org/10.1371/jour... @plos.org

04.02.2026 13:13 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Evaluation of Quality of Care in Chagas Disease Cardiomyopathy | Global Heart

Chronic Chagas heart disease is still difficult to manage. This study outlines what effective care should include at primary, secondary & tertiary levels with real world models showing how simple, scalable steps can improve diagnosis & treatment @worldheart.org globalheartjournal.com/articles/10....

04.02.2026 13:08 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The world remains far off track on health-related SDGs, and R&D gaps continue to undermine progress. At #EB158, we urged WHO Member States to ensure sustained investment in new and effective health tools. Our intervention at @who.int πŸ‘‰ bit.ly/4auqBj2

04.02.2026 08:35 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Despite some progress, the fight against many NTDs remains off track.

At #EB158 we urged Member States to fund NTDs, advance R&D, support inclusive research, & tackle climate-sensitive diseases.

Our intervention at @who.int πŸ‘‰ bit.ly/4auqBj2

03.02.2026 16:31 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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We are deeply saddened by the passing of Sir Nicholas White.

Through a decade as Chair of our Scientific Advisory Committee, Nick guided & strengthened our research with wisdom, integrity & deep commitment to the people we serve. We honour his remarkable legacy and extend our heartfelt condolences.

03.02.2026 13:23 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Poster for the vent. Text reads 'Building out Aedes mosquitoes: Eliminating dengue as an urban threat - a preliminary report from the Lancet Arboviruses Commission.'

Poster for the vent. Text reads 'Building out Aedes mosquitoes: Eliminating dengue as an urban threat - a preliminary report from the Lancet Arboviruses Commission.'

As urban populations grow & the climate warms, a @lshtm.bsky.social RAFT webinar explores how @thelancet.com’s Arbovirus Commission’s Building Out Aedes framework aims to help eliminate mosquito habitats & protect communities from diseases like dengue, Zika & more.

Join here: bit.ly/RAFTroadmapw...

03.02.2026 09:41 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Why India still carries the heaviest burden of neglected tropical diseases On World Neglected Tropical Diseases Day, experts say weak surveillance, underreporting, and gaps in trust are behind India’s toughest last mile.

β€œUnderreporting and weak surveillance continue to cloud the true burden of NTDs,” said Sanjay Sarin, our Asia continental lead, to @nature.com India. β€œCases are often missed in exactly the places where disease risk is highest.”
Read more ‡️
www.nature.com/articles/d44...

30.01.2026 14:52 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Imperial and DNDi strengthen partnership to accelerate treatments for neglected diseases Researchers from Imperial College London and the Drugs for Neglected Diseases initiative (DNDi) met on 19 January to strengthen a growing partnership...

On #WorldNTDDay, @imperialcollegeldn.bsky.social + @dndi.org strengthen their partnership to speed up new treatments for #NeglectedDiseases affecting 1 billion+ people worldwide. 🌍

From #AI to drug discovery, we’re working to turn science into real-world impact.

www.imperial.ac.uk/news/article...

30.01.2026 12:16 πŸ‘ 10 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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🌍 For #WorldNTDDay, we’re spotlighting @moniquewasunna.bsky.social (MSc Clinical Tropical Medicine, 1986; PhD Medicine, 1991) β€” whose leadership advancing equitable access to treatments and clinical research for NTDs across East Africa shows the impact of sustained collaboration.

30.01.2026 09:59 πŸ‘ 8 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1

We look forward to attending @globalhealthedctp3.bsky.social's Info Day on Thursday 5 February!

More info πŸ‘‰ bit.ly/3OcDaXC

30.01.2026 10:24 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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βš•οΈTomorrow is #WorldNTDDay🌐2026, and Chagas Coalition will be supporting it through a webinar with our colleagues from PAHO & @dndi.org. It's about data management related to these 21 neglected diseases

✍️ paho-org.zoom.us/webinar/regi...

On January 30, let's #BeatNTDs & call for #UniteActEliminate

29.01.2026 20:54 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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FGS Mislabeled as an STI: The neglected waterborne Parasite Costing African Women Their Dignity For millions of women and girls across sub-Saharan Africa, routine daily tasks fetching water, washing clothes, bathing in freshwater lakes

"For millions of women and girls across sub-Saharan Africa, routine daily tasks fetching water, washing clothes, bathing in freshwater lakes and rivers expose them to a hidden and devastating disease."
Read more πŸ‘‰ healthbusiness.co.ke/9841/fgs-mis... @HealthBizKE

30.01.2026 08:26 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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πŸ“’ Today is #WorldNTDDay!

Over 1B people are affected by neglected tropical diseases. Too many still lack safe & effective treatments.

πŸ‘‰ Share this post to support science, innovation & global health funding. #EndTheNeglect #BeatNTDs #UniteActEliminate

30.01.2026 07:01 πŸ‘ 4 πŸ” 5 πŸ’¬ 0 πŸ“Œ 3
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🚨 Neglected tropical diseases (NTDs) affect more than 1 billion people worldwide, yet effective treatments and diagnostics are still often unavailable, unsuitable, or unsafe.

#EndTheNeglect #beatNTDs #UniteActEliminate @dndi.org

27.01.2026 15:03 πŸ‘ 5 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Warm congratulations to Prof. Shyam Sundar on receiving the Padma Shri for his outstanding contribution to the diagnosis, treatment & control of #kalaazar. πŸ‘

A well-deserved honour recognizing a lifetime dedicated to improving care & outcomes for affected communities. #beatNTDs #leishmaniasis

28.01.2026 07:16 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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We are not ready for the next pandemic. Latest report from the #100DaysMission finds declining investment in R&D for pandemic countermeasures, with the state of the therapeutics pipeline particularly dire.

Read more πŸ‘‰ ippsecretariat.org/news/pandemi...
@ippsecretariat.org @drluispizarro.bsky.social

27.01.2026 15:37 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0