Super curious what AbbVie's antibody(/ies) is here that they're planning to use
AbbVie and ADARx Pharmaceuticals Announce Collaboration and License Option Agreement to Develop Next-Generation siRNA Therapies Across Multiple Therapeutic Areas news.abbvie.com/2025-05-14-A...
Great to see private financing activity lately in the cardiology space!
Lead is a lncRNA for nHCM about to enter the clinic.
HAYA Therapeutics Raises $65 Million in Series A Funding www.hayatx.com/news-and-pub...
Impressive fundraising. These guys raised $60M less than a year ago. All-in $245M, before starting a clinical trial.
RNA editing startup AIRNA raises $155M for liver and lung disease therapy - endpts.com/rna-editing-...
HERE COMES CHINA'S BOOMING BIOTECH SECTOR
New Odd Lots on yet another area where in the last few years, Chinese firms have suddenly rushed to the technological cutting edge. podcasts.apple.com/us/podcast/h...
Congrats to fellow LabCentral company Gensaic. Awesome news!
Novo bets up to $354M per target on Gensaic’s tissue-selective delivery tech www.fiercebiotech.com/biotech/novo...
This is just terrible for all of these prospective students and for American competitiveness
Graduate student admissions paused and cut back as universities react to Trump orders on research www.statnews.com/2025/02/19/t... via @statnews.com
Super interesting. Better control over synthesis enables better/other delivery approaches, more efficient and lower COGS production, etc.
First direct chemical synthesis of a gene over 1700 nucleotides long
www.chemistryworld.com/news/first-d...
Orig article pubs.rsc.org/en/content/a...
I hope people choose to stay and promote the importance of science for American competitiveness. Push back on harmful policies from here.
Trump policies spark fears of brain drain, threatening to undermine U.S. dominance in biomedicine www.statnews.com/2025/02/12/t... via @statnews.com
Interesting work towards unlocking greater and more localized brain delivery of gene therapy
Focused ultrasound widely broadens AAV-delivered Cas9 distribution and activity www.nature.com/articles/s41...
Sincerely hope this is reversed asap.
Trump administration suspension of global HIV treatment program sparks chaos and fear of lost lives www.statnews.com/2025/01/28/h... via @statnews.com
Atalanta gets $97M boost to take two siRNAs into clinic for rare neuro disorders - endpts.com/atalanta-get...
A bird's-eye view of a former Auschwitz II-Birkenau camp showing a wide dirt pathway flanked by parallel rows of barbed-wire fences. Groups of visitors walk along the path, surrounded by the remnants of brick structures and barracks, now reduced to foundations. Green grass contrasts with the somber history of the site, as the path leads toward a guard tower in the distance.
Auschwitz was at the end of a long process. It did not start from gas chambers.
This hatred was gradually developed by humans. From ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder.
Auschwitz took time.
We're looking to hire a future CMC leader as a Senior Scientist to drive bioconjugation chemistry! Please see the attached JD and email resumes/leads to recruitment@vratatx.com.
www.linkedin.com/posts/robert...
Great to see cardiovascular disease funding continue to take off. Big dollars and names here
Trio behind MyoKardia raise $300 million for new biotech firm focused on heart disease www.statnews.com/2025/01/10/k... via @statnews.com
Theoretical chemist Martin Karplus dies at 94 cen.acs.org/people/obitu...
Gene-editing field sees another merger, this time between Chroma Medicine and Nvelop Therapeutics www.statnews.com/2024/12/11/c... via @statnews.bsky.social
My culinary contribution for today - a potato focaccia pugliese. Happy Thanksgiving!
Every drug I used when I took care of kids with cancer had serious risks.
The only thing that could justify my using them was that their benefits outweighed their risks.
But without proof of efficacy, there’s no way to make that calculation.
Safety & efficacy are 2 sides of the same coin.
Sarepta Therapeutics Announces Global Licensing and Collaboration Agreement with Arrowhead Pharmaceuticals for Multiple Clinical and Preclinical siRNA Programs
ARWR to receive $500 million upfront, $325 million equity investment at a 35% premium
www.businesswire.com/news/home/20...
Novartis is buying gene therapy and neuroscience biotech Kate Therapeutics in a deal worth $1.1 billion.
endpts.com/novartis-buy...
Love this - “The best decisions are made [...] under capital constraint.” See you all around the LabCentral ecosystem.
Former NCI chief and serial biotech entrepreneur raise $70 million to start companies that fail fast www.statnews.com/2024/11/19/j... via @statnews.bsky.social
Sunday morning piano "lessons" from big sister
Relaying a statement from the other site from my district's congressman, Jake Auchincloss
New draft guidance from the FDA - Nonclinical Safety Assessment of Oligonucleotide-Based Therapeutics www.fda.gov/regulatory-i...
RIP Pulmatrix. I interned there a couple times, right before and right after senior year of college. Great people, interesting tech out of the Langer lab iirc.
Pulmatrix and Cullgen Announce Proposed Merger $PULM ir.pulmatrix.com/2024-11-13-P...
$RNA going after PLN and PRKAG2 (not part of BMS agreement)
Avidity Biosciences Announces New Precision Cardiology Development Candidates to Treat Rare Genetic Cardiomyopathies and Provides First Look at Next-Generation Technology Innovations aviditybiosciences.investorroom.com/2024-11-12-A...
Sarepta is discontinuing its SRP-5051 program www.parentprojectmd.org/sarepta-anno...
AbbVie to Acquire Aliada Therapeutics, Strengthening Focus in Alzheimer's Disease and Neuroscience Pipeline
Private co funded by JJDC, RACap, Orbimed, Sanofi Ventures. Platform delivers cargo across the BBB using TfR and CD98
www.prnewswire.com/news-release...
