@ahmig.es
bioinformatician, predoc researcher and PhD candidate @pathogenomics.bsky.social (@i2sysbio.es) | SARS-CoV-2 evolution and metabolic reconstruction of pathogens biotech BSc USAL & bioinfo MSc @uv.es 💻 github.com/ahmig | ahmig.es 📍 València, Spain
Happy Bioinformatics Day!🧬💻Celebrate the power of data for understanding life at every level. In @pathogenomics.bsky.social we combine experiments with bioinformatics to understand bacterial evolution, virulence, and infection dynamics. #SoyBioinformatica @paururo.bsky.social @ahmig.es @i2sysbio.es
3D rendering of a glass-like sculpturecof a metabolic network over a night photograph of a building
Sharing my entry for @i2sysbio.es's BioVision 2026! "MTB 20:02" is a night photograph of the metabolic network of M. tuberculosis hovering near our building at night (made in Blender, based on iEK1011)
methods 🤓👉 tangled.org/ahmig.es/biovision2026
#b3d
"you need to learn how to use gAI or you'll get left behind!"
counterpoint!
the absolute fastest way to render yourself unemployable is to build your skillset around a tool that does your thinking for you, that everyone has access to, and that one company can change or take away at any time
🥈🥈🥈🗣️🗣️‼️
🎖️ El #I2SysBio ha sido reconocido como el segundo instituto más sostenible del @csic.es
🟢Este logro es fruto del trabajo constante de nuestra Comisión de Sostenibilidad, impulsando iniciativas ambientales, sociales y económicas.
Euphoric for my institute @i2sysbio.es receiving the 2nd @csic.es Sustainability Prize. Proud of the tireless & impactful work of our Committee. Especially happy to share recognition with friends from IDAEA & @geo3bcn-csic.bsky.social. Congrats @icmabcsic.bsky.social and @ibmb-csic.bsky.social
2️⃣ Desde el @i2sysbio.es presentan sus medidas y, entre ellas, su trabajo para obtener las certificaciones internacionales de investigación sostenible
Happy birthday to one of my favourite haters, Charles Darwin
VIPERA v1.3.0 is out!! 🐍🐍🐍
under the hood: visualization decoupled from computation, faster allele freq distance calculations using a custom tool (afwdist) and improved performance
on the user side: same inputs and outputs, a few options removed or renamed, clearer docs and a prettier report
🧪👇
VIPERA v1.2.2 is out!! 🐍
now you can swap in different stats (useful for non-linear allele freq trends). also: new Docker images on release, containerized CI, updated envs, and minor bug fixes for smoother, reproducible intra-patient SARS-CoV-2 analyses
🧪👉 github.com/PathoGenOmics-Lab/VIPERA
Orbit diagram of interstellar object A11pl3Z
FACT THREAD on New Interstellar Object #A11pl3Z
This story unfolded pretty fast yesterday for a few reasons. The object was discovered on July 1st UTC by the Asteroid Terrestrial-impact Last Alert System, or ATLAS team. A #NASA funded survey at the University of Hawaii. atlas.fallingstar.com 🔭🧪
So uh, there's a new interstellar object discovered at Chile yesterday. Name is A11pl3Z, has a hyperbolic trajectory of eccentricity 14±4 (WTF). Currently appmag 18, 4 AU away from Earth, and coming to 2 AU perihelion this October.
(tagging🔭☄️)
Observing it with remote scope rn, calling astronomers..
On June 20, #I2SysBio (@csic.es - @uv.es) hosted Alva Saa from association PRISMA, who shared ten key measures to foster #LGTBIQA+ 🏳️🌈 inclusion in #science. The talk addressed actions like staff training, safe reporting channels, and collective visibility in research.
🌐 i2sysbio.es/communicatio...
VIPERA v1.2.1 is here!! 🐍🐍🐍
Our workflow for SARS-CoV-2 intra-patient evolution analysis now fully supports Snakemake 8/9 (with dedicated CI tests), BIONJ trees, richer reports, added config parameters, modular Snakefiles and more! 🧪👉 github.com/PathoGenOmics-Lab/VIPERA
A photo of a group of people with the Alhambra in the back
Just back from MCEB 2025 in Granada! I presented our year-long work expanding VIPERA🐍 to help us better track pathogen evolution, here at @pathogenomics.bsky.social - @i2sysbio.bsky.social. I learned so much and returned full of ideas! Thanks to @bcbhubcsic.bsky.social for funding my attendance! 🧪
Gentes de Bluesky, firmad esto que es importante: iniciativa ciudadana europea para prohibir las "terapias" de conversión de personas LGTBIQ+. NO es un change.org, puede suponer un cambio legal real. Y no lo dejéis para luego, que se acaba el sábado. eci.ec.europa.eu/043/public/#...
fotografía de buitre leonado
fotografía de buitre leonado
fotografía de buitre leonado
🐥 #birdwatching #birds
typeset version is out!! read about artifacts in #SARS-CoV-2 genomes (and more) from the comfort of your browser here 👇👇🧪
doi.org/10.1093/ve/v...
Un equipo multidisciplinar liderado por el Instituto de Biología Integrativa de Sistemas (I2SysBio), centro mixto del Consejo Superior de Investigaciones Científicas (CSIC) y la Universitat de València (UV), acaba de publicar un estudio que descubre una nueva perspectiva sobre la capacidad del virus SARS-CoV-2 para mutar e infectar a los humanos. Mediante una revisión de la base de datos genéticos del virus más utilizada durante la pandemia, el equipo de investigación halló ‘falsos positivos’ en su capacidad de reparación de las deleciones, un proceso que restaura secciones del genoma viral que afecta la capacidad del virus para replicarse o evadir el sistema inmunológico del huésped. En el trabajo, publicado en la revista Virus Evolution, participan investigadores del Instituto de Biomedicina de Valencia (IBV) del CSIC y del Instituto de Investigación Sanitaria La Fe (IIS-La Fe). El trabajo liderado por el grupo de Patogenómica del I2SysBio en colaboración con el grupo de Biología Viral del mismo instituto ofrece una perspectiva innovadora sobre ciertos cambios genéticos raros en la proteína spike del SARS-CoV-2, la ‘llave’ que utiliza el coronavirus para infectar nuestras células. La investigación se centró en los llamados eventos de reparación de deleciones en esta proteína, en los que el virus aparenta corregir su genoma.
Un equipo liderado por el @i2sysbio.bsky.social publica una investigación que halla errores en las secuencias genéticas del #coronavirus incluidas en la mayor base de datos mundial. También participan @ibv-csic.bsky.social y el IIS La Fe.
delegacion.comunitatvalenciana.csic.es/hallan-error...
By mining GISAID, researchers from I2SysBio uncover sequencing artifacts in SARS-CoV-2. Many repair mutations in the spike protein were due to errors in data processing. #covid19 #viruses #microsky🧪🦠💻🧬 More info: www.i2sysbio.es/communicatio... ⬇️
happy to share our new study! 🧪
while exploring how often #sars-cov-2 "repairs" deletions in BA.1, we found significant genome artifacts in GISAID 🤯 we compared with raw reads from ENA + tested the effects in vitro. turns out, data processing matters a lot 📉
check it out!! doi.org/10.1093/ve/v...
Oferta de beca de investigación en nuestro instituto con la excelente supervisora Mireia Coscollá @pathogenomics.bsky.social . Proyecto enfocado en bioinformática, tema patógenos 🧪🦠🧫🧬🖥👩🔬
#member
Our institute hosts the exhibition “Train the feminist gaze”, promoted by the City Council of Valencia @ajuntament-vlc.bsky.social to highlight the inequalities between women and men present in everyday life and in areas such as art or science 🧪 www.i2sysbio.es/communicatio... #WomenInSTEM 👩🔬
hi! I'd love to be added: scholar.google.com/citations?us... thanks!
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X
https://go.nature.com/42tH8Ai
Our research institute I2SysBio🇪🇸 has created a starter pack for researchers in systems biology, everybody is welcome, write us if you want to be added 🔬🧫🧬🖥🦑🦠🌱🦟🪳🪸🌾
a picture taken during my flash talk about large-scale data analysis based on our tool, VIPERA (Viral Intra-Patient Evolution Reporting and Analysis), at the I SEBiBC congress
Had a great time sharing an exciting new direction for VIPERA🐍 at the I congress of the Spanish Society of Bioinformatics and Computational Biology (SEBiBC)! Can't wait for the next one 🗣️🗣️
