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Aanchal

@origichals

Human | Learner | PhD researcher studying SUMOylation (SUMO:SIM interactions) using Biochemistry and Structural Biology approach @msuskiewicz.bsky.social lab @cnrs.fr

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18.11.2024
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Latest posts by Aanchal @origichals

-by Marianne Williamson, A Return to Love: Reflections on the Principles of "A Course in Miracles"

19.02.2026 19:05 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

It's not just in some of us; it's in everyone. And as we let our own light shine, we unconsciously give other people permission to do the same. As we are liberated from our own fear, our presence automatically liberates others.

19.02.2026 19:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

You are a child of God. Your playing small does not serve the world. There is nothing enlightened about shrinking so that other people won't feel insecure around you. We are all meant to shine, as children do. We were born to make manifest the glory of God that is within us.

19.02.2026 19:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Our deepest fear is not that we are inadequate. Our deepest fear is that we are powerful beyond measure. It is our light, not our darkness that most frightens us. We ask ourselves, 'Who am I to be brilliant, gorgeous, talented, fabulous?' Actually, who are you not to be?

19.02.2026 19:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

We celebrate the posters, the reports, the publications, the successful gels, the elution peaks,saturated curves, working controls and the tiny wins only we understand.

Different people. Different worlds.
One lab. One team.

-A student (frm team of Castaing/Suskiewicz at @cbm-upr4301.bsky.social)

12.02.2026 21:20 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

From sharing brains to sharing the AKTA slot,
from giving last-minute science advice to decoding mysterious results together,
from compulsory coffee breaks to β€œfive-minute” chats,
from stressed experiment days to random laughter in the lab, we show up for each other.

12.02.2026 21:07 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

We’re more than experiments and data points. We’re inside jokes whispered over centrifuges, shared snacks during long purifications, emergency buffers passed like treasure, borrowed pens that never quite return...

12.02.2026 21:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

One is owned by a cat.
Another probably wants five more.
One enjoys a good glass of wine.
Another appreciates a slow cigar.

We are students with different hobbies, different dreams, different cultures, different languages, and different stories.

12.02.2026 21:05 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

One of us is absolutely obsessed with capybaras.
Another can’t stop talking about dachshunds.
One lives and breathes anime.
Another is powered entirely by romance novels.
One expresses personality through funky socks.
Another could survive on potatoes alone.

12.02.2026 21:05 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

A gentle, fun reminder that science isn’t just about answers, but about the long, curious wandering that gets you there. Prof. Kleanthous shares his lab’s journey with warmth, making bacteriocins feel like companions along the way rather than just subjects of study.

02.02.2026 19:39 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algaeβ€”the pyrenoidβ€”to find out… 🧡

Preprint here!:
www.biorxiv.org/content/10.6...

@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid

30.01.2026 15:20 πŸ‘ 78 πŸ” 37 πŸ’¬ 1 πŸ“Œ 5

How are these JCs organized? Like everyome reads the paper and someone presents in a presentation, or some other way?

19.01.2026 16:25 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Oh yeah! When nothings' working in the lab, ShinChan is the go to. Science might give up, ShinChan won't :D

15.01.2026 17:52 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Stop scrolling and post two characters that bring you happiness :)

15.01.2026 14:06 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Client Challenge

Evolution’s cheat code in action: www.nature.com/articles/s41...

12.01.2026 08:59 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I updated ipSAE code to handle Boltz2 files properly -- non-standard chainIDs/order, PDB input as well as mmCIF; other pull requests. github.com/DunbrackLab/.... Also updated preprint--fixed Latin grammar error in title - very embarrassing and added new figure. www.biorxiv.org/content/10.1...

03.01.2026 11:06 πŸ‘ 15 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Magic incoming from our team soon....

02.12.2025 08:36 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

The truth is, every institute (especially mine, @cbm-upr4301.bsky.social ) is full of these unsung heroes- people who lift us up, keep us going, and make everything work. And appreciating them isn't just important… it's absolutely worth it!!!

02.12.2025 07:05 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Then there’s StΓ©phane, always ready with brilliant scientific suggestions like a walking, talking idea generator.

Christine, the financial wizard who guides us through budgets the way Gandalf guides hobbits.

Isabelle, whose posters for student defenses are so good they deserve their own exhibition

02.12.2025 06:56 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Like Franck, who heroically drives all the way to Paris so we can make it to a conference basically our logistical superhero,but with better conversation.

Or Laetitia, who embarks on an epic quest to find my lost poster box, as if she’s starring in β€œIndiana Jones and the Missing Research Artifact.”

02.12.2025 06:55 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

There are moments in life when certain people nearby just show up for you- no fanfare, no fuss, just pure goodness. And honestly? These people deserve a standing ovation, confetti cannons, and maybe even a parade.

02.12.2025 06:53 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Interesting. David Baker's paper states the same. I will try these, thank you so much Alexis.

24.11.2025 18:48 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

This is amazing! How many amino acids did you choose for designing the mini-binder? Also, are there any other criteria's you applied for this?

24.11.2025 15:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

C'est interessant. I wonder what the phosphorylation findings are....

21.11.2025 09:16 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thrilled to share our PI’s new publication exploring filament ambition of FAM118A/FAM118B in NSMB.

These proteins show remarkable self-assembly with clear implications for their biological roles, proving once again that structure n function go hand in hand or in this case, subunit by subunit.

17.11.2025 23:12 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Science just pulled up a chair at the kitchen table: a new paper explores the physics behind droplet outbursts when slicing onions
www.pnas.org/doi/10.1073/...

07.11.2025 18:10 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Grateful to be listed as an author in this insightful review. All credits to Marcin Sir for his generosity, considering my contribution was more of a cameo than a lead role.

06.11.2025 09:46 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Hydrophobic effect: oil droplets merging in water to hide their fears

SPR: measuring the rhythm of a heartbeat between two molecules (real-time tracking of association and dissociation)

Protein networks: a social graph- hubs, connectors, and transient acquaintances...

How would your Science be?

29.10.2025 20:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

ITC: warmth of a handshake (measures the heat released or absorbed during binding)

Multivalency: Velcro - strength from many tiny hooks (multiple weak interactions sum into stability)

SEC: Like watching who walks out of a crowded room together (Separates complexes by size and shape)

29.10.2025 20:40 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

X ray crystallography: a frozen poem written in diffraction spots

Binding energy landscape: mountain valley guiding a river into its lowest path (energy minimization)

Molecular dynamics: Like watching a city breathe in atomic time (every atom moves, interacts, and evolves)

29.10.2025 20:36 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0