Thomas Goetz

On medicine, with Dr. Eric Topol Whatever happened to matching drugs to our DNA?

Whatever happened to pharmacogenomics - matching drugs to our DNA? In new episode of Drug Story, @EricTopol tells me what happened - and why it still holds promise. www.drugstory.co/p/on-medicin...

Drug Story is now a featured show on Apple Podcasts!

Take a listen. podcasts.apple.com/us/podcast/d...

Bay Area cycling community rallies after Alex Pretti’s death Rides in San Francisco and Oakland are part of a global tribute to the nurse killed in Minneapolis by federal authorities.

My first byline at @sfstandard.com :

Bay Area cycling community rallies after Alex Pretti’s death

sfstandard.com/2026/01/30/a...

(i left a couple obv errors in there if u can c)

things I miss: in tha 80s punk groups would cover ‘stupid’ 70s songs.
eg
1. Replacements: Black diamond (Kiss)
2. Soul Asylum: jukebox Hero (Foreigner)
3. Sonic Youth: Sweet Jane (velvet Underground)
4. Killdozer: Sweet Home Alabama (Tom Petty)

@clarajeffery.bsky.social @romanmars.bsky.social

Thank you @davideagleman.bsky.social for having me on to talk drugs and Drug Story!

Now this is cool: Apple selected Drug Story as a featured New Show!

No idea exactly how this happens, but I expect it helps that so many folks have given Drug Story a generous 5 star rating at Apple Podcasts. (HINT, HINT)

‘Drug Story’ Explores the Disease Business one Med at A Time | KQED Airdate: Tuesday, January 6 at 9 AM In today’s world, it seems there's a remedy for every modern ailment. Anxiety. Diabetes. Heart disease. There’s a pill for that! But what do the drugs we take to ma...

The pros, cons, and controversies of prescription drugs - loved talking with Alexis Madrigal on @kqedforum.bsky.social this morning. Take a listen!
www.kqed.org/forum/201010...

For our first newsletter of the year, co-founder @thgoetz.bsky.social introduces his new podcast, Drug Story, that explores the state of health in the US and how we got here -- one blockbuster drug at a time: mailchi.mp/9729a35a1ac4...

One of my fave Gehry buildings was the house he built for himself in the middle of a neighborhood in Santa Monica, CA. Actually, he didn't build it - he bought an old bungalow and added to it until it became... this. en.wikipedia.org/wiki/Gehry_R...

Drug Story Trailer Introducing a new podcast about the disease business, told one drug at a time. First episode: January 6, 2026.

Did you know that Xanax is name-dropped in rap songs as much as Hennessy, Rolex, or Air Jordans?
My new project: DRUG STORY, a podcast about the disease business, one drug at a time.

The first episode drops on Tuesday, January 6.
check out the trailer here: www.drugstory.co/p/drug-story...

Pick: in history, Top 10 medications that have been/treated:

a) most significant drugs (pro/con) of past 100 years
b) most significant conditions of past 100 years
c) just a crazy story behind it or the disease?

(dropping a sneak preview of something cool this week)

How America Got Hooked on Ultraprocessed Foods (Gift Article) They promised convenience and cheap nutrition. But they became one of the greatest health threats of our time.

With the news on ultraprocessed foods this week, it's worth going back to this excellent explainer, from @alicecallahan.bsky.social, on how we got to where we are today: www.nytimes.com/interactive/...

I am super duper excited to read this. Charles Mann is so good at this stuff.

Two Hundred Years to Flatten the Curve How generations of meddlesome public health campaigns changed everyday life — and made life twice as long as it used to be

Shameless plug:

For a year, I've been working on a series about the vast systems that underlie life in most of the world. Built up over generations, these systems are the cathedrals of our time--but all too few of us know anything about them, and they're all at risk of failing. Here's the latest:

Happy to rake a read! 😁

If you need me today, I'm doing the fucking news.

“Good luck to all” is just …

Why urban designers should think like doctors ‘Architectural Epidemiology’ offers a radical prescription for cities: a new design framework that builds health into real estate.

Health in all design ...

www.fastcompany.com/91377661/why...

Ejaculation Frequency and Risk of Prostate Cancer: Updated Results with an Additional Decade of Follow-up Evidence suggests that ejaculation frequency may be inversely related to the risk of prostate cancer (PCa), a disease for which few modifiable risk fa…

As they say, I will just leave this… here. www.sciencedirect.com/science/arti...

Tremor?

Of course - just a little bump

Earthquake bluesky

apropos of nothing, here's the wine list at Mar A Lago lagomar.com/wp-content/u...

*Now* i get it - when people say "do your own research" - they mean once the NIH, CDC, NSF, and other government-funded science all shuts down.

This is true. My team at iodine did for $1.1m what a previous team had failed to do for $150m for fda. Instead of praise we got rousted.

The Great American Enshitification begins

if anybody is backing up gov websites, please add ies.ed.gov/ncee/wwc to the list - a clearinghouse of what works in education policy, hosted by dept. of education. essential documentation of how to teach!

Bryan Johnson is the living embodiment of Goodhart's law Bryan Johnson is an entrepreneur who is trying to use technology to avoid dying.

A really good assessment of how Bryan Johnson is chasing the wrong metrics, by Gregory Katz gregorykatz.substack.com/p/bryan-john...

David Sacks claims there's 'substantial evidence' that DeepSeek used OpenAI's models to train its own | TechCrunch David Sacks said there's evidence that DeepSeek 'distilled' knowledge from OpenAI's models, a process that Sacks equated to theft.

What I've read so far, the "evidence" is that they can't figure out how else DeepSeek could've done it, which, hrm.

Also, *if* someone stole OpenAI's data, call the police, using copyrighted material without paying its creators is a crime, good point.

techcrunch.com/2025/01/28/d...