Excited to share this preprint about the identification of TBK1 molecular glue degraders in a collaboration between NEOsphere Biotechnologies, @pmeier.bsky.social, and the Centre for Protein degradation @icr.ac.uk www.biorxiv.org/content/10.6...
It was a privilege to join the amazing Climb of Life to fundraise for the basic, translational, and clinical cancer research we do @ICR_London.
www.linkedin.com/posts/the-in...
In a couple of weeks Sonja and I are back in the beautiful Lake District for The Climb of Life, as we raise vital funds for the cancer research of the Institute of Cancer Research (@icr.ac.uk).If you would lke to supoort us, you can do so via this link. www.justgiving.com/page/sonja-r...
Applications for PhD studentships @icr.ac.uk are now open. Are you interested in a PhD in structural biology applied to proteins involved in cancer? Check out the PhD-project available in my group. You can apply via the ICR website. Closing date is 16 November 2016.
www.icr.ac.uk/study-and-ca...
Thank you for a great day with us @icr.ac.uk and wonderful drug discovery talk @hartungingo.bsky.social!
A nice blog about the acoustic dispensing robotics used in cancer drug discovery @icr.ac.uk. A big thank you to Mark Stubbs and Caroline Ewens for explaining it all! www.icr.ac.uk/research-and...
NEWS: NICE has recommended capivasertib for advanced #BreastCancer.
The decision makes the targeted drug available, in combination with fulvestrant, for some NHS patients with the most common type of breast cancer.
Read more about the history of the drug⬇️
www.icr.ac.uk/about-us/icr...
Fondly remember Jan for his enthusiasm, rigorous science, and the kind person that he was.
The Centre for Cancer Drug Discovery @icr.ac.uk looking fantastic in today's evening sun
Sharp et al (2024) Integrating fragment-based screening with targeted protein degradation and genetic rescue to explore eIF4E function. Nat Commun 15 10037 #TPD #FBDD #FBLD #MedChem #DrugDesign #DrugDiscovery #OpenAccess #chemsky 🧪
doi.org/10.1038/s414...
Today is #InternationalWomensDay 👏
We are incredibly proud to celebrate the women of the ICR who are dedicated, driven, and determined to make a difference.
You inspire us every day 👩🔬👩💻👩💼
#IWD2025 #AccelerateAction
Today Jan Drenth would have been 100 years, but sadly he passed away last week.
He was the founding father of structural biology in the Netherlands and his modesty, his gentle humor and his generosity set the spirit for the amazing environment in Groningen where i did my PhD.
It's #InternationalMotherLanguageDay 🌍
We're proud of our diverse community who are dedicated to defeating cancer.
Our staff and students from across the globe come from a variety of backgrounds and cultures, and speak different languages, but are united by one mission ♥️
We are recruiting a Higher Scientific Officer experienced in recombinant protein production and assay development to join an exciting collaboration to develop novel small molecule-controlled molecular switches to modulate CAR-T cell activity.
jobs.icr.ac.uk/vacancies/11...
Are you interested to work in cancer drug discovery? Come and join us, we are recruiting a protein crystallographer to strengthen our structure-based drug discovery efforts.
jobs.icr.ac.uk/vacancies/11...
📰 Prof Paul Workman, our former CEO, along with his team in our Centre for Cancer Drug Discovery, have made a breakthrough that could lead to new drugs for #chordoma — a rare #BoneCancer that led to the death of his mother.
Read more in @theguardian.com ⤵️
www.theguardian.com/science/2025...
On International Day of Women and Girls in Science, we're celebrating our awe-inspiring women helping to defeat cancer 👩🔬👏
Hear from Professor Ros Eeles, Professor Helen McNair
(The Royal Marsden NHS) and ICR PhD students Clara, Nivetha, and Anna about what #IDWGS means to them ⬇️
#WomenInScience
We’re delighted that The Scottish Medicines Consortium (SMC) has today recommended olaparib for use in advanced #BreastCancer.
The treatment offers the chance of longer, healthier lives for people with breast cancer caused by faulty #BRCA1 or #BRCA2 genes.
scottishmedicines.org.uk/about-us/lat...
Will these tools further exacerbate biases in the literature: if the opinion of those who write many papers gets fed into their training more than the opinion of those who write sparingly?
Scientists should use their precious time to do good science, not to write many papers...
I’ve unfortunately needed to add more material to my post from yesterday. The re-election of Donald Trump is looking like the biggest act of American self-destruction since the Civil War.
Same link, new title and some updates.
ICYMI
The Institute of Cancer Research have made amazing inroads in treating advanced prostate cancer with the new NXP800 drug.
So proud to represent the Institute - they embody the ambition and pursuit of pragmatic hope that Sutton, and the whole country, really needs.
Looking forward to speak at the 2nd Biophysics for Drug Discovery Summit (ter.li/39kb11) about the integrated biophysical approaches used in our BCL6 project. Collaborative drug discovery with Swen Hoelder, @chemb.bsky.social and @temt-icr.bsky.social at @icrlondon.bsky.social.
We have a vacancy in assay development, compound profiling, and screening to help progress the cancer drug discovery projects of the Centre for Cancer Drug Discovery @icrlondon.bsky.social. If you are interested please check out the details below.
jobs.icr.ac.uk/vacancies/11...
If you are interested in a PhD studentship in chemical biology linked to brain cancer in children, check out the position Gary Newton and myself have available. @icrlondon.bsky.social. www.icr.ac.uk/study-and-ca...
Beautiful and frosty morning @icrlondon.bsky.social today.
@cancerresearchuk.org Windsor Fellowship and Black in Cancer funded PhD place at @icrlondon.bsky.social and @imperialcollegeldn.bsky.social
Aimed at students from Black heritage background who want to pursue a career in cancer research : www.findaphd.com/phds/project... (1/2)
🆕 We're getting in on the act with an ICR research #StarterPack. Check it out! ⤵️
Let us know if you're a #cancer researcher at the ICR and The Royal Marsden but not in the pack. 💬
#CancerResearch #CanSky #OncSky
go.bsky.app/EGXU5V1
That awkward moment when someone publishes a paper saying that they can’t find any evidence that your compounds bind to what your own series of papers say that they bind to. . .
Great collaboration with @chemb.bsky.social!
