Grant Challen

Check out our new paper describing a previously unexplored relationship between DNMT3A and telomeres. A huge team effort! Comments and new collaborations welcome!

Pretty much every mid-40s dude tonight

Let’s go Happy !!

Cell-extrinsic factors contribute toward myeloid-biased expansion in Tet2-mutant clonal hematopoiesis Hematopoietic stem cells (HSCs) acquire somatic mutations throughout life, with the frequency of mutational incidence increasing with age [1]. Occasionally, certain mutations confer a fitness advantag...

Excited to see the first commentary in Experimental Hematology (@isehsociety.bsky.social)! Kudos to Aishwarya, Linde ‪@lindemileslab.bsky.social, and Grant @challenlab.bsky.social for highlighting recent papers in Exp Hem on cell-extrinsic factors in Tet2-mutant clonal hematopoiesis!! bit.ly/4k3pEAI

Special guest at lab meeting today thanks @thekinglab.bsky.social !!!

Stand up for science!

Trying to get the word out at WashU!

Believe it or not this is Kansas not Antarctica !!!