Simon Anders

MYTH: As commander-in-chief, Trump has the authority to take military action. FACT: It is unconstitutional for a U.S. president to declare war without the approval of the Knesset.

Trump’s War On Iran: Myth Vs. Fact https://theonion.com/trumps-war-on-iran-myth-vs-fact/

In Deutschland denken Frauen heute darüber nach, ihre Babys abzutreiben, weil die Wohnung zu klein ist. Keine bezahlbare Wohnung, keine Kinder. Und die CDU will die Partei von Familie und Heimat sein? In den 60er Jahren schuf die CDU "das Wohnungswunder"! Für Adenauer war…

Wissenschaftliche*r Geschäftsführer*in (w/m/d) - Zentrum für Molekulare Biologie der Universität Heidelberg - Universität Heidelberg Universität Heidelberg bietet Stelle als Wissenschaftliche*r Geschäftsführer*in (w/m/d) - Zentrum für Molekulare Biologie der Universität Heidelberg in Heidelberg - jetzt bewerben!

We are are searching a scientific manager for the ZMBH. This position requires a life sciences PhD & excellent German skills, therefore the advertisement is formulated in German. Very good English skills are needed as well. You are welcome to share the ad:
www.academics.de/jobs/wissens...

Benchmarking EGF signaling pathway inference using phosphoproteomics and kinase-substrate interactions - Nature Communications To what extent can large-scale approaches accurately reconstruct classic signaling pathways? Here, authors revisit the EGF pathway using phosphoproteomics and kinase-substrate interactions

Is the linear map of cell signaling a myth?
New research suggests the reality of cellular networks is more complex.
@savitski-lab.bsky.social & @saezlab.bsky.social combined experimental and computational expertise to test how we map kinase–substrate interactions.
www.nature.com/articles/s41...

Screenshot of an X post by Republicans Against Trump reporting claims that commanders at multiple U.S. bases told troops the Iran war is part of “God’s plan” and linked to Armageddon. Below is a photo of Trump standing with several evangelical leaders praying around him.

The religious right has infiltrated far into our military with disturbing consequences.

The main project of my PhD 🧬🔬 is out: we developed single-cell lentiMPRA, a lentivirus-based method to measure enhancer activity and transcriptomes at single-cell resolution. We then applied sc-lentiMPRA to fully synthetic enhancers 🧩...

🔗 doi.org/10.64898/202...

Now, synthetic enhancers with single cells - great work by @juruehle.bsky.social : www.biorxiv.org/content/10.6...

Screenshot of the "Does that use a lot of energy?" online app

Hannah Ritchie has built a fun little tool where you can compare energy usage of various products and activities.

This is super helpful imho, because it's so hard to develop intuitions even just about the scales involved here.

hannahritchie.substack.com/p/does-that-...

Chance and Consensus in Peer Review (1981) www.science.org/doi/10.1126/... tltle: it's a lottery system)

The molecular evolution of vertebrate organs Nature Ecology & Evolution - This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms...

Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here:
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜

Democrats Wear White Flag Pins To SOTU To Indicate Surrender

Democrats Wear White Flag Pins To SOTU To Indicate Surrender

THERE’S POWER IN BOYCOTTING!

See how thunderstorms create ghostly UV sparks on the tips of trees Thunderstorms can generate weak electrical discharges on the plants underneath, but until now, they had never been observed in nature

Thunderstorms can generate weak electrical discharges on the plants underneath, but until now, they had never been observed in nature

Press the Red Button, Dave A small study at LANL has real-world biosecurity relevance: evaluating whether AI can transfer tacit laboratory skill to novices.

Press the Red Button, Dave. A small study at LANL has real-world #biosecurity relevance: evaluating whether AI can transfer tacit laboratory skill to novices. doi.org/10.59350/6e0...

Illness Is rampant among children trapped in ICE’s massive jail in Texas The number of people held at the notorious Dilley immigration jail has nearly tripled since October.

THIS 👇is pure EVIL.

Cross-species comparison reveals therapeutic vulnerabilities halting glioblastoma progression - Nature Communications Understanding the growth dynamics of GBMs can help expand therapeutic options. Here, authors use a cross-species computational approach to compare GBM cells to healthy neural stem cells, identifying p...

📖 Our new pseudotime alignment tool ptalign identifies Wnt antagonist SFRP1 as central for glioblastoma cell activation, opening new avenues for patient stratification and therapeutic avenues.

🔗 lnkd.in/ees8bhNY
by @Leo Carl Foerster, Oguzhan Kaya et al.

#glioblastoma #pseudotime #neurobiology

ggannotate: interactively add annotations to your {ggplot2} plots by pointing and clicking github.com/MattCowgill/... #Rstats

Absolutely savage, I love it.

With all the excitement about AI giving us answers, we often forget that the real trick is to figure out what is the question.

8/ 🤘 For those about to rock (around the Christmas tree), we salute you 🎸🎄: Isabelle Seufert & our team from @dkfz.bsky.social & BioQuant & @akispapantonis.bsky.social, Philipp Mallm, @s-anders.bsky.social & Petros Kolovos labs with support from @spp2202.bsky.social & @mspacealliance.bsky.social.

1/ 🎄 We got our Christmas present today: "Two distinct chromatin modules regulate proinflammatory gene expression" is now published @natcellbio.nature.com doi.org/10.1038/s415.... Our study introduces a scATAC-seq-based framework for genome-wide analysis of gene regulation features.

Screenshot from project 2025 that says By statute or regulation, CDC guidance must be prohibited from taking on a prescriptive character. For example, never again should CDC officials be allowed to say in their official capacity that school children "should be" masked or vaccinated (through a schedule or otherwise) or prohibited from learning in a school building. Such decisions should be left to parents and medical providers. We have learned that when CDC says what people "should" do, it readily becomes a "must" backed by severe punishments, including criminal penalties. CDC should report on the risks and effectiveness of all infectious disease-mitigation measures dispassionately and leave the "should" and "must" policy calls to politically accountable parties. Conflicts of Interest. There was a time when the CDC could not take money

It is utterly catastrophic that RFK Jr. plans to end CDC recommendations for most childhood vaccines.

It’s a betrayal of science, ethics, compassion, and the people of the United States.

And it was also a specific goal of Project 2025 (page 254).

This is the most alarming story I’ve read today. Giving up the fight before it’s started

ISCO (Innovations in Single-Cell OMICS) will be back in beautiful Barcelona!

🗓️ 28th/29th of May 2026
📍Barcelona Biomedical Research Park @prbb.org (beachfront!)

Keynotes: @bartdeplancke.bsky.social and @bocklab.bsky.social

Submit your abstract and present your research!

www.isco-conference.eu

The CNRS is breaking free from the Web of Science From January 1st 2026, the CNRS will cut access to one of the largest commercial bibliometric databases, Clarivate Analytics'

One step in the right direction from @cnrs.fr . Here’s hoping others will follow and we can get some more space for actual science. 🧪 www.cnrs.fr/en/update/cn...

A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines Feng et al. present the first genome-scale CRISPR interference perturbation map with scRNA-seq readout across many genetic backgrounds in human pluripotent cells, pioneering population-scale CRISPR pe...

Happy to see this out now in Cell Genomics: A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines: www.cell.com/cell-genomic...

Ensembl 2026 Abstract. The Ensembl project (https://www.ensembl.org) is a public and open resource providing access to genomes, annotations, high-quality tools, and met

Our Ensembl 2026 paper is out!
Learn about 1,900+ new genomes, expanded pangenome support, new regulation interfaces, and what’s coming in our 2026 releases.
doi.org/10.1093/nar/gkaf1239

Postdoctoral fellow - Petsalaki Group - NetworkCommons Your group The Petsalaki, Saez-Rodriguez (EMBL-EBI) and Korcsmáros (Imperial College) groups develop cutting-edge computational and AI approaches to unravel cellular signalling and gene regulation fro...

#Postdoc alert! We are looking for motivated individual with experience in computational systems biology to join our NetworkCommons initiative to benchmark and democratise network contextualisation methods across multiple applications. Deadline Dec 17th link here: tinyurl.com/yrrzxa94

Comic. Panels up to the 10-year point are grayed out. New panels since the Ten Years comic, which chronicles the first ten years of PERSON 1's journey with cancer: (1) [two people in bed] PERSON 1 (woman): One more chapter? PERSON 2 (man): Don’t we both have to get up early? PERSON 1: Nnnnnggggh PERSON 2: Sure, good point. (2) [many people wearing masks, walking while looking at graphs on their phones] (3) [birds landing on people] PERSON 2 in beanie and scarf: Hah! They like *my* seeds best. PERSON 1 in scarf holding phone with a bird sitting on it: Wait, how do I take a picture of this one? (4) [two people rowing boats with tree landscape] (5) [Person 1 carries overflowing stack of things to Person 2 in bed] PERSON 1: I brought you honey lemon tea, more pillows, a cinnamon roll, Tylenol, another blanket, a– PERSON 2: It was just Appendicitis, I’m really– PERSON 1: *It is my turn to take care of you and I am going to do it right!* (6) [Two people in car] (7) [still in car) PERSON 1: Oh my god. PERSON 2: Oh my god. (8) [car driving] PERSON 1: Pull over! PERSON 2: I am! (9) [both people get out of car] (10) [Large colored panel of aurora borealis over water with both people looking on] (11) [Person 1 sits against tree while Person 2 lies on the ground] PERSON 1: Fifteen years. No sign of the cancer. (12) I *am* having some weird symptoms. Joint pain. Fatigue. I think I’m losing my close-up vision. PERSON 2: Yeah. Me too. (13) PERSON 2: I think we’re getting old. (14) PERSON 1: I guess that’s okay. PERSON 2: It’s all I wanted.

Fifteen Years

xkcd.com/3172/

Frikkin amazing stuff.