@dzne.science
Dedicated to advancing the scientific understanding of neurodegenerative diseases - from mechanisms to diagnosis, therapy, and prevention (such as AD, PD or ALS). 🔗 Imprint: https://dzne.de/en/imprint 🔗 Data Protection: https://dzne.de/en/data-protection/
New paper out: TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.: Feiten, Astrid Feentje; Dahm, Kilian; Schlepckow, Kai; et al.
Nature Communications Vol. 17, no. 1, p. 2002 | Thanks for sharing #dzne #papers
Blood phosphorylated Tau elevation in immunoglobulin light chain and transthyretin amyloidosis.
Stephan Kaeser, Stephanie Schultz, Anna Hofmann.
@natmed.nature.com (2026).
DOI: 10.1038/s41591-026-04272-2
🩸 A blood protein seen as an early marker of Alzheimer’s 🧠may also play a role in other diseases: Researchers at DZNE and @hih-tuebingen.bsky.social found elevated phosphorylated tau (pTau) levels in two rare conditions affecting the heart 💓 and kidneys.
👉 www.dzne.de/en/im-fokus/...
New paper out: Alterations in cerebrospinal fluid levels of myelin- and oligodendrocyte-related proteins in sporadic Creutzfeldt–Jakob disease: Maass, Fabian; Thomas, Carolina; Kurvits, Lille; et al.
Acta Neuropathologica Communications Vol. 14, no. 1, p. 51 | Thanks for sharing #dzne #papers
New paper out: A physically and mentally active lifestyle relates to younger brain and cognitive age: Behrenbruch, Niklas; Schwarck, Svenja; Schumann-Werner, Beate; et al.
GeroScience | Thanks for sharing #dzne #papers
New paper out: Proton channel Hv1 modulates microglial responses to neurological disorders: Stratmann, Maite; Gagliardi, Caterina; Capasso, Melania
Frontiers in biophysics Vol. 3, p. 1681011 | Thanks for sharing #dzne #papers
New paper out: Partizipation in der VersorgungsforschungParticipation in health services research: Hoffmann-Hoffrichter, Anna Louisa; Manietta, Christina; Rommerskirch-Manietta, Mike; et al.
Zeitschrift für Gerontologie und Geriatrie | Thanks for sharing #dzne #papers
New paper out: Social networks of people with dementia: Roles of informal and formal contact persons: Hofbauer, Lena M.; Knecht, Hanna L.; Rodriguez, Francisca S.
Journal of public health | Thanks for sharing #dzne #papers
New paper out: Clinical course and prognosis of chronic autoimmune neuropathies requiring intensive care: a retrospective cohort study.: Preßler, Hannah; Schwarz, Lisa; Streit, Simon; et al.
Journal of neurology Vol. 273, no. 2, p. 165 | Thanks for sharing #dzne #papers
New paper out: Serum levels of neurofilament light chain (NfL) and glial fibrillary acid protein (GFAP) in patients with asymptomatic and symptomatic carotid artery stenosis.: Jansen, Robin; Wagenhäuser, Markus U; Kölsche, Tristan; et al.
JVS-vascular science Vol.… | Thanks for sharing #dzne #papers
New paper out: Persistent viral control status is associated with enhanced innate immune responses in people with HIV-1: C. dos Santos, Jéssica; Groenendijk, Albert L.; Ruijten, Suzanne D. E.; et al.
iScience Vol. 29, no. 3, p. 114807 - | Thanks for sharing #dzne #papers
New paper out: Low number of patients qualifying for amyloid targeting immunotherapy.: Jessen, Frank
The journal of prevention of Alzheimer's disease Vol. 13, no. 3, p. 100516 - | Thanks for sharing #dzne #papers
New paper out: Dysphagia in Multiple System Atrophy Does Not Correlate with Serum Neurofilament Light Chain and Glial Fibrillary Acidic Protein.: Klietz, Martin; Pannewitz-Makaj, Katharina; Baacke, Franziska; et al.
Movement disorders p. mds.70092 | Thanks for sharing #dzne #papers
New paper out: Quantitative susceptibility mapping of brain iron in adult ADHD.: Schulze, Marcel; Autenrieth, Erik; Aslan, Behrem; et al.
Frontiers in psychiatry Vol. 17, p. 1735191 | Thanks for sharing #dzne #papers
New paper out: Phagocytes as plaque catalysts: Human macrophages generate seeding-competent Aβ42 fibrils with cross-seeding activity.: Konstantoulea, Katerina; Ramakers, Meine; Borrie, Sarah C; et al.
Proceedings of the National Academy of Sciences of the United… | Thanks for sharing #dzne #papers
New paper out: Zusammenführen, was zusammengehört: Neuropsychiatrie: Spruth, Eike Jakob; Gemenetzi, Maria; Altenstein, Slawek; et al.
Nervenheilkunde Vol. 45, no. 01/02, p. 10 - 11 | Thanks for sharing #dzne #papers
New paper out: Real-Time Emotion Recognition Performance of Mobile Devices: A Detailed Analysis of Camera and TrueDepth Sensors Using Apple's ARKit.: Aldenhoven, Céline Madeleine; Nissen, Leon; Heinemann, Marie; et al.
Sensors Vol. 26, no. 3, p. 1060 - | Thanks for sharing #dzne #papers
New paper out: Microglia-Derived Extracellular Vesicles from Alzheimer's Disease Patients Carry miRNAs Driving a Neuroinflammatory Response.: Arbaciauskaite, Skaiste; Silvestri, Simona; Luo, Pingyan; et al.
Molecular neurobiology Vol. 63, no. 1, p. 435 | Thanks for sharing #dzne #papers
New paper out: Informational complexity as a neural marker of cognitive reserve.: Stolp, Laura; Mandke, Kanad N; Mediano, Pedro Am; et al.
Brain and cognition Vol. 193, p. 106392 - | Thanks for sharing #dzne #papers
New paper out: The impact of lifestyle restrictions on memory in older adults.: McMaster, Jessica M V; Gellersen, Helena M; Korkki, Saana M; et al.
PLOS ONE Vol. 21, no. 2, p. e0342458 - | Thanks for sharing #dzne #papers
New paper out: Loss-of-function variants in the CAPN1 activator CD99L2 cause X-linked spastic ataxia.: Menden, Benita; Incebacak Eltemur, Rana D; Demidov, German; et al.
Nature Communications Vol. 17, no. 1, p. 1698 | Thanks for sharing #dzne #papers
New paper out: Longitudinal modeling of Post-COVID-19 condition over three years: A machine learning approach using clinical, neuropsychological, and fluid markers.: Walders, Julia; Wetz, Sophie; Costa, Ana Sofia; et al.
Scientific reports Vol. 16, no. 1, p. 6517 | Thanks for sharing #dzne #papers
New paper out: Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis.: Gao, Jincheng; Bader, Almke; Linder, Monika I; et al.
Cell death & disease Vol. 17, no. 1, p. 180 | Thanks for sharing #dzne #papers
New paper out: Fear of progression in Parkinson's disease: Role of age and occupational status.: D'Souza, Simone; Tekampe, Esther; Falkenburger, Björn; et al.
Journal of Parkinson's Disease Vol. 16, no. 1, p. 170 - 176 | Thanks for sharing #dzne #papers
New paper out: Serum NfL, but not GFAP, differentiates primary lateral sclerosis from adrenomyeloneuropathy and hereditary spastic paraplegia type 4.: Kessler, Christoph; Wilke, Carlo; Hengel, Holger; et al.
Amyotrophic lateral sclerosis & frontotemporal… | Thanks for sharing #dzne #papers
New paper out: Comparison of online radiologists and large language model chatbots in responding to common radiology-related questions in Chinese: a cross-sectional comparative analysis: Ji, Jiang; Li, Chenguang; Fu, Yibin; et al.
Quantitative imaging in medicine… | Thanks for sharing #dzne #papers
New paper out: The flexible synapse – How mossy fiber architecture adapts to changing needs: Bruentgens, Felicitas; Schmitz, Dietmar; Orlando, Marta
Progress in neurobiology Vol. 258, p. 102882 - | Thanks for sharing #dzne #papers
New paper out: Automatically measured speech intelligibility models bulbar-specific disease severity and progression in Amyotrophic Lateral Sclerosis.: Tröger, Johannes; Rouvalis, Andreas; Dörr, Felix; et al.
Amyotrophic lateral sclerosis & frontotemporal… | Thanks for sharing #dzne #papers
New paper out: Pioglitazone attenuates complement-mediated microglial synaptic engulfment in an Alzheimer's disease model.: Zu, Juan; Li, Cong; Cui, Mochen; et al.
Brain Vol. 149, no. 2, p. 668 - 679 | Thanks for sharing #dzne #papers