Trending
Sean Davis's Avatar

Sean Davis

@seandavi

73
Followers
13
Following
20
Posts
09.06.2024
Joined
Posts Following

Latest posts by Sean Davis @seandavi

Preview
Microbial Pathogenesis & Host Response Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

Alert! The abstract deadline for the Microbial Pathogenesis & Host Response meeting has been extended to July 7 meetings.cshl.edu/meetings.asp...

23.06.2025 20:24 👍 38 🔁 23 💬 1 📌 2
The RBioc Book A collection of chapters more than a book, but….

Course materials from the most recent iteration of the Statistical Analysis of Genome-scale Data course at @cshlnews.bsky.social.

seandavi.github.io/RBiocBook/

Thanks to many contributors and to several years' worth of students. Always a work-in-progress...

24.06.2025 17:50 👍 1 🔁 0 💬 0 📌 0

/2 Per @statnews.com:
At [NHGRI], the entire comms office was eliminated Tu, along w/the offices of policy, science education, procurement, & the whole division of management..
Bonham’s dismissal leaves the institute w/o anyone in charge or able to offer the final sign-off on issuing new grants.

02.04.2025 04:18 👍 3 🔁 1 💬 1 📌 0

They've put Christine Grady, chief of the department of bioethics at the NIH’s Clinical Center on admin leave. I've worked w/her a lot. A WONDERFUL bioethicist (& person—a saint!).
Fired for personal reasons? She's Fauci's wife.

They have no shame.

02.04.2025 04:13 👍 83 🔁 20 💬 4 📌 4

What are they doing? And why? @dahlialithwick.bsky.social

02.03.2025 13:15 👍 0 🔁 1 💬 0 📌 0

Added. Thanks, @trishaclare.bsky.social. For folks unfamiliar with eRA Commons (public.era.nih.gov), it is the online system that allows users to manage grants for the National Institutes of Health (NIH). While it is down, the NIH grants process will be further curtailed.

02.03.2025 14:42 👍 0 🔁 0 💬 1 📌 0

Given the recent and ongoing service interruptions in PubMed, National Library of Medicine, NIH Reporter, etc., I put together a status page that covers a few key resources and some NIH institute pages.
stats.uptimerobot.com/Zrqh8AhvKn
Let me know what other sites you'd like to see added.

02.03.2025 11:55 👍 20 🔁 10 💬 3 📌 1
Post image

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...

01.03.2025 18:07 👍 3134 🔁 1385 💬 61 📌 94
Preview
National Center for Biotechnology InformationTwitterFacebookLinkedInGitHubNCBI Insights BlogTwitterFacebookYoutube

Anyone else finding that ncbi.nlm.nih.gov and related subdomains are down right now?

01.03.2025 17:45 👍 0 🔁 0 💬 0 📌 0

The @bioconductor.bsky.social Zenodo community accepts any contributions related to or Bioconductor. It is a great way to share software, of course, but also slides, talks, posters, workflows, etc. All contributions to zenodo get a doi.

zenodo.org/communities/...

24.02.2025 21:29 👍 6 🔁 3 💬 0 📌 0
Preview
GBCC2025 Cold Spring Harbor Laboratory (CSHL), New York June 23-26, 2025

📣 GBCC2025 Abstracts & Registration Open!

Join us June 23-26, 2025, at Cold Spring Harbor Lab for the first Galaxy & Bioconductor Community Conference.

🗓 Abstract Deadline: April 1
🔗 Submit/Register: gbcc2025.org

#GBCC2025 #Bioconductor #DataScience #OpenSource

11.02.2025 22:01 👍 9 🔁 5 💬 0 📌 0
Post image

@msftresearch.bsky.social and @carnegiemellon.bsky.social published a study examining self-reported reductions in cognitive effort and confidence among knowledge workers utilizing #AI. Not the complete picture, but provides insight, challenges, and opportunities.
www.microsoft.com/en-us/resear...

11.02.2025 17:38 👍 0 🔁 0 💬 0 📌 0
Post image

scGPT-spatial: Continual Pretraining of Single-Cell Foundation Model for Spatial Transcriptomics https://www.biorxiv.org/content/10.1101/2025.02.05.636714v1 🧬🖥️🧪 https://github.com/bowang-lab/scGPT-spatial

10.02.2025 19:30 👍 7 🔁 4 💬 0 📌 0
Preview
GitHub - seandavi/state-cancer-profile-scraper: Bulk access and download state cancer profiles data Bulk access and download state cancer profiles data - seandavi/state-cancer-profile-scraper

The data at statecancerprofiles.cancer.gov are a valuable source of information about nationwide #cancer incidence and mortality. To address the lack of an API or data download, we have generated data extracts for dashboards, data integration, #epidemiology research, etc. github.com/seandavi/sta...

11.02.2025 00:00 👍 0 🔁 0 💬 0 📌 0
Preview
The Burden of Reviewing LLM-Generated Content Large language models (LLMs) in health care aim to reduce the cognitive and administrative burden for health care professionals. Yet the accuracy and completeness of LLM-generated material is still...

ai.nejm.org/doi/full/10....

08.02.2025 23:30 👍 0 🔁 0 💬 0 📌 0
A Cross-Sectional Study of GPT-4–Based Plain Language Translation of Clinical Notes to Improve Patient Comprehension of Disease Course and Management The 21st Century Cures Act provides patients with access to their clinical notes, but most patients, particularly those with limited health literacy, have difficulty understanding and utilizing the...

ai.nejm.org/doi/full/10....

08.02.2025 23:29 👍 0 🔁 0 💬 0 📌 0

In case folks are interested in contacting their congresspeople about the NIH indirect cuts with some estimates of what they would mean for institutions in their state, here are some estimates based on published F&A rates and funding ... let me know if you want a particular state

08.02.2025 14:14 👍 2163 🔁 833 💬 188 📌 79
Preview
‘Despair is not an option’ — how scientists can help protect federal research Government scientists in the US must be clear-eyed and continue to serve the public.

www.nature.com/articles/d41...

08.02.2025 19:10 👍 0 🔁 0 💬 0 📌 0

Thanks for the shout out. The real heros are the folks who submit data and the dedicated folks at NCBI GEO and NLM who maintain the data resources. We are reminded that such resources are not to be taken for granted....

08.02.2025 18:22 👍 1 🔁 0 💬 0 📌 0
Preview
How are researchers using AI? Survey reveals pros and cons for science Despite strong interest in using artificial intelligence to make research faster, easier and more accessible, researchers say they need more support to navigate its possibilities.

www.nature.com/articles/d41...

08.02.2025 11:59 👍 0 🔁 0 💬 0 📌 0
Preview
Integration of 168,000 samples reveals global patterns of the human gut microbiome The Human Microbiome Compendium is a unified database of publicly available human gut microbiome 16S samples, built with the integrated data from hundreds of independent projects. The compendium is us...

We’re thrilled that our first paper on the Human Microbiome Compendium, an integrated dataset of over 168,000 uniformly processed human gut microbiome samples, is officially out today in Cell! @richabdill.com @blekhman.bsky.social www.cell.com/cell/fulltex...

22.01.2025 17:31 👍 100 🔁 44 💬 3 📌 6
Preview
A foundation model for joint segmentation, detection and recognition of biomedical objects across nine modalities - Nature Methods BiomedParse is a foundation model for image analysis that uses a joint learning approach to jointly conduct segmentation, detection and recognition and offer state-of-the-art performance across a wide...

www.nature.com/articles/s41...

18.11.2024 18:40 👍 0 🔁 0 💬 0 📌 0
Preview
GitHub - dockur/macos: OSX (macOS) inside a Docker container. OSX (macOS) inside a Docker container. Contribute to dockur/macos development by creating an account on GitHub.

#macos in #docker.
github.com/dockur/macos

#mswindows in #docker.
github.com/dockur/windows

14.11.2024 15:22 👍 1 🔁 0 💬 0 📌 0
Preview
Natural Language Processing–Assessed Unmet Medical and Social Needs This cross-sectional study uses a large natural language processing model to examine unmet medical and social needs based on cancer-related fundraising stories in the US.

Application of ChatGPT in #oncology #research analyzed 91k US cancer crowdfunding stories and found that over one-third reported medical or social hardships like housing or food insecurity, with few meeting fundraising goals.
jamanetwork.com/journals/jam...

14.11.2024 13:53 👍 2 🔁 0 💬 0 📌 0

I've embraced these new technologies as both a student (aren't we all?) and an educator (of adults), encouraging students to experiment, share their experiences transparently, and understand that active learning can take many forms. Not all candy canes and roses, but this stuff is here to stay.

14.11.2024 13:38 👍 0 🔁 0 💬 0 📌 0
Preview
GitHub - seandavi/awesome-single-cell: Community-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc. Community-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc. - seandavi/awesome-single-cell

Six years on, github.com/seandavi/awe... is still going strong. Contributions welcome. Fastest growing category recently has been spatial transcriptomics.
#compbio #singlecell #transcriptomics #genomics #awesome-list

13.11.2024 19:25 👍 13 🔁 3 💬 3 📌 0
Post image

This is wild and futuristic. A virtual lab comprised of multiple A.I. (5) agents designed potent nanobodies vs SARS-CoV-2 with minimal human oversight. t.co/09smMPwHCY

13.11.2024 15:24 👍 111 🔁 31 💬 6 📌 3
Preview
Commit: Online Groups with Participation Commitments In spite of efforts to increase participation, many online groups struggle to survive past the initial days, as members leave and activity atrophies. We argue that a main assumption of online group de...

This paper argues that online spaces become ghost towns because it's too easy to lurk without contributing, and that asking people to regularly re-commit—or the incoming messages start getting muted—reverses the trend. arxiv.org/abs/2410.23267

It works! #cscw2024 paper by @popowski.bsky.social
.

01.11.2024 17:56 👍 37 🔁 13 💬 0 📌 2
Preview
A large-scale audit of dataset licensing and attribution in AI Nature Machine Intelligence - The Data Provenance Initiative audits over 1,800 text artificial intelligence (AI) datasets, analysing trends, permissions of use and global representation. It exposes...

A large-scale audit of dataset licensing & attribution in #AI text datasets. rdcu.be/dZzux Dataset licenses are frequently missing or wrong on popular dataset hosting sites.

Interactive Data Provenance Explorer: dataprovenance.org

#DataTransparency #AIethics #MachineLearning

08.11.2024 13:30 👍 1 🔁 0 💬 0 📌 0
Post image Post image Post image Post image

A framework for sharing of clinical and genetic data for precision medicine applications https://www.nature.com/articles/s41591-024-03239-5 🧬🖥️ https://github.com/G2Lab/PrecisionChain

03.09.2024 20:00 👍 6 🔁 2 💬 0 📌 0