Excited to share currently confirmed speakers for HCA Asia 2026 (lnkd.in/gEQPj3Gk)!
#SingleCell #Genomics #SpatialBiology #SpatialOmics #HumanCellAtlas #SingleCell #transcriptomics #multiomics #Spatial_transcriptomics
@ozsinglecell.bsky.social
@lornegenome.bsky.social
GPU-accelerated single-cell analysis at scale with rapids-singlecell #SingleCell ๐งช๐งฌ๐ฅ๏ธ
https://arxiv.org/abs/2603.02402
Differential analysis of genomics count data with edge #SingleCell ๐งช๐งฌ๐ฅ๏ธ
https://www.biorxiv.org/content/10.64898/2026.02.16.706223v1
Evaluating Single-Cell Perturbation Response Models Is Far from Straightforward #SingleCell ๐งช๐งฌ๐ฅ๏ธ
https://www.biorxiv.org/content/10.64898/2026.02.14.705879v1
Registration for the HCA Asia Meeting on 2-4 November, 2026 is now open! The #HCA2026Asia meeting will be held in Perth, Australia, and online, and is hosted by @alforrest.bsky.social. Please register at buff.ly/gADDEnC
๐ฅ๏ธ ๐งฌ #Genomics #SingleCell #Spatial #HumanCellAtlas
This was a great read, thank you for sharing.
A a figure showing comparison of connectomeDB2025 to other ligand-receptor pair databases.
connectomeDB2025: Quality matters!
โ
3,579 ligand-receptor pairs supported by 2,803 papers
โ
14 vertebrates
โ >2,900 unsupported pairs from other DBs excluded
connectomedb.org
academic.oup.com/nar/advance-...
@JARamilowski @sakura_maezono @rui_hou_ @weitao_lin @yen_yeow + team
@ginaravenscroft.bsky.social & #NARF are collecting impact statements from Australian researchers
โ Please consider sharing your story about the impact of Australia's chronic underfunding of science and biomedical research.โ
lnkd.in/g8A_PAZG
1/
Every opportunity politicians provide for you to tell them about how chronic underfunding of research in Australia is affecting your particular fields, people, working conditions etc. is extremely important.
Fill out the form here: lnkd.in/g8A_PAZG
If your #NHMRC ideas grant was unsuccessful and you have a story to share about the impact of this on your #biomedicalresearch, career, team - get in touch. Federal DOH have asked #NARF to collect stories of impact of low funding. #SaveOzScience #DiscoveriesNeedDollars #EMCRs
Last chance! Early bird rates and oral presentation abstract submissions for Lorne Genome ๐๐ง๐ ๐๐จ๐ฏ๐๐ฆ๐๐๐ซ ๐๐ญ๐ก, ๐๐๐๐ - only one week away: https://www.lornegenome.org/registrations
We have a fantastic lineup of national and international speakers: https://www.lornegenome.org/speakers. Join us!
velotest: Statistical assessment of RNA velocity embeddings reveals quality differences for reliable trajectory visualizations #SingleCell ๐งช๐งฌ๐ฅ๏ธ
https://www.biorxiv.org/content/10.1101/2025.10.26.683064v1
Igniting full-length isoform analysis in single-cell and spatial RNA-seq data with FLAMESv2 https://www.biorxiv.org/content/10.1101/2025.10.19.683327v1
Don't forget to register and submit an abstract for the ๐๐จ๐ซ๐ง๐ ๐๐๐ง๐จ๐ฆ๐ ๐๐๐๐!
๐๐ก๐ข๐ฌ ๐ฐ๐๐๐ค'๐ฌ ๐ฌ๐ฉ๐๐๐ค๐๐ซ ๐ฌ๐ฉ๐จ๐ญ๐ฅ๐ข๐ ๐ก๐ญ: ๐๐ซ๐จ๐ ๐๐ซ๐๐ง๐๐ ๐๐ง๐๐ซ๐๐ฐ๐ฌ, a leading systems biologist whose research focuses on mapping genetic interaction networks and protein localisation patterns in yeast and human cells.
The Fragile X mental retardation protein (FMRP) coordinates an epigenetic checkpoint in neural progenitor cells https://www.biorxiv.org/content/10.1101/2025.08.31.673358v1
Whole-transcriptome-scale and isoform-resolved spatial imaging of single cells in complex tissues #SingleCell ๐งช๐งฌ๐ฅ๏ธ
https://www.biorxiv.org/content/10.1101/2025.08.27.672533v1
๐งฌ The 2025 Emma Whitelaw ECR publication award is now open!
Full T&Cs and application form are on the AEpiA website www.aepia.org.au/emma-whitela...
We can't wait to see the exciting research that has been published over the last year!
#epigenetics #ECR #research #AEpiA
My generation had to deal with datasets where Excel had autocorrected gene names to dates. Future generations are going to have to deal with the hallucinations of slopbots.
Disentangling the influences of pre- and postnatal periods on human cortical microstructure https://www.biorxiv.org/content/10.1101/2025.08.12.669812v1
Especially important for all the microscopy Widdors out there.
Beautiful paper, congrats all involved.
Worth a watch:
Head of Signal, Meredith Whittaker, on so-called "agentic AI" and the difference between how it's described in the marketing and what access and control it would actually require to work as advertised.
This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u
A short thread follows 1/n
Extrinsic biological stochasticity and technical noise normalization of single-cell RNA sequencing data https://www.biorxiv.org/content/10.1101/2025.05.11.653373v1
Can't remember who said it, but using ChatGPT for your college essays is like using a forklift to move the weights around at the gym.
It's the process that's important to your development, not the end product.
It was new to me and our lab as well. Thanks for sharing.
genomebiology.biomedcentral.com/articles/10....
Quite an indictment of some of the current single cell "virtual cell" foundation models. Even for the relatively mundane applications, cell labeling, batch correction etc, they are poor compared to much simpler & cheaper methods.
A package of research papers from the MICrONS (Machine Intelligence from Cortical Networks) consortium in Nature and Nature Methods provides a detailed map of mouse brain cell structure and connections, offering insights into how they relate to activity in the mouse brain. ๐งช
How accurate are 'gene regulatory networks' inferred from scRNA-seq data?
This comprehensive analysis in @naturemethods.bsky.social concludes:
1. The areas under the precision-recall curve are moderate
2. Methods not using pseudotime-ordered cells are more accurate
MeCP2 controls dendritic morphogenesis via miR-199a-mediated Qki downregulation https://www.biorxiv.org/content/10.1101/2025.04.04.642981v1
