James Conway

@alzheimersresearchuk.org

I’m speaking at the Alzheimer’s Research UK Conference 2026 about our new paper, “Intestinal macrophages modulate synucleinopathy along the gut–brain axis”. Can’t wait to connect, share research, and learn alongside researchers at every stage of their careers.
#ARUKconf

Targeting the gut's immune system could tackle early stages of Parkinson's New research reveals how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice led by scientists at the UK D...

New research has revealed how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice co-led by Dr @soyonhonglab.bsky.social & Dr Tim Bartels @ukdri.ac.uk @uclqsion.bsky.social @uclbrainscience.bsky.social

Targeting the gut's immune system could tackle early stages of Parkinson's New research, led by Dr Soyon Hong and Dr Tim Bartels at the UK DRI at UCL, has revealed how Parkinson’s spreads from the gut to the brain, with the hel

Could targeting the gut's immune system tackle the early stages of Parkinson's? 🧠

A new study from @soyonhonglab.bsky.social & Tim Bartels (UK DRI at UCL) has revealed how Parkinson’s spreads from the gut to the brain - with the help of immune cells.

Read more 👉 www.ukdri.ac.uk/news-and-eve...

Intestinal macrophages modulate synucleinopathy along the gut–brain axis - Nature Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understa...

Our paper is finally out!

We position intestinal muscularis macrophages as early initiators of α-synuclein pathology and dopaminergic neurodegeneration in Parkinson’s models. They also drive local CD4⁺ T cell expansion, which subsequently migrates from gut to brain

www.nature.com/articles/s41...

The glia‐immune network: Astrocytes and oligodendrocytes as microglial co‐ordinators in health and disease Abstract figure legend The glia-immune network involves the communication(s) of glia via immune signalling pathways. In neuro-homeostasis these pathways have been shown to modulate key processes such...

New topical review from Verity Mitchener,
Mille Thackray and Lorena Arancibia-Cárcamo of
@ukdri.ac.uk on the glia-immune network in health and disease, with a focus on how astrocytes and oligodendrocytes coordinate microglia in Alzheimer's disease pathology

Cryo-Et image of a brain extracellular vesicle

Benjamin Ryskeldi-Falcon’s @brfalcon.bsky.social group in the LMB’s Neurobiology Division, with Karen Duff's group at the UK DRI, have discovered that tau filaments are tethered to the membranes of extracellular vesicles in #Alzheimers

Read more: www2.mrc-lmb.cam.ac.uk/cryo-et-reve...
#LMBResearch

🧠Sharing this Starter Pack again as the list has now reached 80 people! A great mix of Profs/PIs/Post-docs/PhDs/Technicians.

Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋

go.bsky.app/S6FfsTp

Can I be added too please? - I’m a postdoc working on synucleinopathies