Ackermann Lab

The next chapter for SPP 2363 has begun!🌟 The second funding phase is officially underway. A warm welcome to all the new PIs and students! We're excited to build upon the momentum of our first phase and and driving new discoveries together🚀
#spp2363 #MML #Collaboration #Network

Late-Stage C–H Diversifications with Ambiphilic α-Bromoboronates: Versatile Access to Transformable meta-Boroalkyl Scaffolds The ruthenium-catalyzed meta-C–H alkylation is an increasingly powerful strategy in the arena of remote C–H activation. Currently, the synthesis utility of this strategy is compromised owing to its re...

🚀 Fresh off the press in ACS Catalysis!
Check out our efficient and modular approach with Ru-catalyzed meta-C–H functionalization using readily available α-bromoboronates, achieved under exceedingly mild conditions with high chemo- and site-selectivity. 👏

pubs.acs.org/doi/10.1021/...

Register now for the Beilstein Organic Chemistry Symposium “Technologies shaping future directions in synthesis”, 📅 October 14–16, 2025, in Limburg, Germany. 
🔗 https://tinyurl.com/nmpnwhzr
#BeilsteinShapingSynthesis2025

@annagslater.bsky.social
@catalysis-lab.bsky.social
@tnoel82.bsky.social

Multiple Atropo Selectivity by κ2‐N,O‐Oxazoline Urea Ligands in Cobaltaelectro‐Catalyzed C─H Activations: Decoding Selectivity with Data Science Integration Cobaltaelectro-catalyzed C─H activation enables simultaneous construction of indoles with up to two distinct C─N chiral axes. High stereoselectivity derives from newly developed chiral κ2-N,O-oxazoli...

Check out our newly designed κ²-N,O-oxazoline urea ligands enabling multiple atropo-selective outcomes in Co-electrocatalyzed C–H activations. MVLR model reveals ligand-substrate synergy backed by mechanistic insight.🔍 Now in ChemistryEurope doi.org/10.1002/ceur...
Big congrats to the team! 🎊

Integrating a multitask graph neural network with DFT calculations for site-selectivity prediction of arenes and mechanistic knowledge generation - Nature Synthesis A multitask graph neural network is developed with mechanism-informed reaction graphs for site-selectivity prediction of ruthenium-catalysed C‒H functionalization of arenes. The extrapolative predicti...

Now online & open access:

Article by Xinran Chen, Zi-Jing Zhang, Xin Hong & Lutz Ackermann

Integrating a multitask graph neural network with DFT calculations for site-selectivity prediction of arenes and mechanistic knowledge generation

www.nature.com/articles/s44...
#ChemSky

Struktur eines Nickel-Komplexes ermittelt durch Röntgenstrukturanalyse Foto: Ackermann Group

Prof. Dr. Lutz Ackermann Foto: Universität Göttingen

Nachhaltige Wege in der #Molekülherstellung: Ein Forschungsteam unserer Uni (@catalysis-lab.bsky.social) nutzte Nickel und Kobalt, um chemische Reaktionen zu beschleunigen und nachhaltige Energiesysteme zu fördern – mit #Wasserstoff als Nebenprodukt:
s.gwdg.de/tVER3W; doi.org/g87mkn

🎉 Congratulations to Tristan von Münchow @tvonmuenchow.bsky.social on successfully defending his PhD thesis! 🎓 Tristan has made significant contributions to enantioselective 3d metallaelectro-catalysis ⚡🧪. Wishing him all the best in his future endeavors!💐

Enantioselective C–H annulations enabled by either nickel- or cobalt-electrocatalysed C–H activation for catalyst-controlled chemodivergence Nature Catalysis, Published online: 07 March 2025; doi:10.1038/s41929-025-01306-9Controlling the selectivity of electrocatalysed C–H activation with earth-abundant base metals can increase its synthetic impact. Now chemodivergence of an electrocatalysed…

New online! Enantioselective C–H annulations enabled by either nickel- or cobalt-electrocatalysed C–H activation for catalyst-controlled chemodivergence

The collections feature authors including @hayneschemlab.bsky.social, @akhuc.bsky.social, @karabren.bsky.social, @demirselly.bsky.social, @unsworthchem.bsky.social, @chemashlee.bsky.social, @bessettatiana.bsky.social, @catalysis-lab.bsky.social & @flpchemist.bsky.social, with more articles to come!

Difunctionalization of bicyclo[1.1.0]butanes enabled by merging C−C cleavage and ruthenium-catalysed remote C−H activation - Nature Synthesis The high fraction of sp3-hybridized carbon atoms (Fsp3) in cyclobutanes makes them promising bioisosteres for arenes. Now by combining bicyclo[1.1.0]butane C–C activation with remote meta-C–H function...

Now online & open access:

Article by Shan Chen, Zhimin Xu, Binbin Yuan, Xue-Ya Gou & Lutz Ackermann

Difunctionalization of bicyclo[1.1.0]butanes enabled by merging C−C cleavage and ruthenium-catalysed remote C−H activation

www.nature.com/articles/s44...
#ChemSky

It’s always a joy inspiring the next generation of scientists! 🎉🎄🎅
Had a wonderful time exploring the wonders of science with our young guests. 🔬
@ResearchWohler @UniGoettingen
#ScienceIsFun🧪 #KinderUniGÖ #CuriousMinds✨ #NextGenScientists

Thank you very much for the hospitality and great organization @ISCHA2024 in Bombay

We’re happy to announce our presence on Bluesky. Follow us @catalysis-lab.bsky.social for updates, insights, and discoveries!
#Chemistry #Catalysis #science

website at www.ackermann.chemie.uni-goettingen.de