Casey Greene's Avatar

Casey Greene

@casey.greenelab.com

Chair of the Department of Biomedical Informatics at the University of Colorado School of Medicine. Research: transcriptomics, machine learning, public data - pick two of three. He/him. Views mine, not employer's.

4,713
Followers
471
Following
81
Posts
01.05.2023
Joined
Posts Following

Latest posts by Casey Greene @casey.greenelab.com

Preview
CU Anschutz Recruits National Leader to Launch Functional Personalized Medicine Initiative CU Anschutz welcomes Alice Soragni to launch a Functional Personalized Medicine Initiative using rapid tumor organoid testing to guide treatment decisions.

Happy to share this new, very intentional chapter. I have left UCLA after 14 years to join the University of Colorado Anschutz as Professor of Biomedical Informatics and Neurosurgery and the inaugural Marsico Chair in Excellence in Functional Precision Medicine/n

news.cuanschutz.edu/dbmi/cu-ansc...

10.02.2026 21:32 πŸ‘ 192 πŸ” 30 πŸ’¬ 40 πŸ“Œ 1

This fall, the Data Lab is hitting the road to present some of our tools and projects during these exciting events. Here’s where you can find us! 🧡

08.09.2025 15:52 πŸ‘ 0 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Negative grant review: "This is not a research application, it's a rambling discourse about contemporary issues in bioinformatics"

Negative grant review: "This is not a research application, it's a rambling discourse about contemporary issues in bioinformatics"

Happy upcoming Pioneer Award Application Day to all who celebrate. I was mentioning that the best review comment I've ever gotten came from the related DP2 (New Innovator) mechanism. Enjoy this throwback to #GrantReviewGreatstHits as the deadline gets closer! May you all do better than I've done!

30.08.2025 14:09 πŸ‘ 41 πŸ” 2 πŸ’¬ 2 πŸ“Œ 1
Preview
Beyond AlphaFold: how AI is decoding the grammar of the genome Scientists are seeking to decipher the role of non-coding DNA in the human genome, helped by a suite of artificial-intelligence tools.

"I want to vibe code the genome"

β€”the illustrious @casey.greenelab.com

as quoted by @jperkel.bsky.social @nature.com 🧬πŸ–₯️ #MLSky www.nature.com/articles/d41...

18.08.2025 21:42 πŸ‘ 22 πŸ” 10 πŸ’¬ 1 πŸ“Œ 0
Preview
a man is dancing with dinosaurs in the background Alt: A man is fending off dinosaurs in Jurassic Park

Day 3 of vibe coding the genome: velociraptors now code review pull requests.

19.08.2025 02:28 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Two people on the Anschutz Health Sciences Building patio on a cloudy day at the CU Anschutz Medical Campus. They are overlooking Denver and the mountains

Two people on the Anschutz Health Sciences Building patio on a cloudy day at the CU Anschutz Medical Campus. They are overlooking Denver and the mountains

CU Anschutz 🀝UCLA

We were thrilled to host @alice.soragnilab.com from UCLA at @cuanschutz.bsky.social. She’s teaming up with @casey.greenelab.com to drive innovation and improve patient outcomes. This collaboration is a powerful example of how partnerships accelerate scientific discovery.

15.08.2025 20:25 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

What is the point of published abstracts?? Does anyone find them useful for anything? As if we don't already have enough clutter in the literature 😳

23.07.2025 14:00 πŸ‘ 19 πŸ” 4 πŸ’¬ 11 πŸ“Œ 2
Post image

Now up in #BOSC2025 is our Ed Board Member @monimunozto.bsky.social talking about the AI/ML readiness of biomedical data through the Bridge2AI project #ISMBECCB2025 #ISMB2025

21.07.2025 16:27 πŸ‘ 7 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
A deep profile of gene expression across 18 human cancers Data for "A deep profile of gene expression across 18 human cancers"

Study 50K cancer transcriptomes through deep learning. data: figshare.com/articles/da...
paper www.biorxiv.org/content/10....

02.07.2025 14:15 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Preview
Deep profiling of gene expression across 18 human cancers - Nature Biomedical Engineering Using unsupervised deep learning to generate low-dimensional latent spaces for gene-expression data can unveil biological insight across cancers.

FYI I'm pretty sure this one ended up getting published after peer review here: www.nature.com/articles/s41...

02.07.2025 14:16 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Preview
AI in Healthcare: Results Over Hype What is AI in healthcare? How is my doctor using AI? An artificial intelligence expert explains how healthcare is uses AI for patients, medical research.

This Q&A with @casey.greenelab.com provides a nice summary of the current state of #ArtificialInteligence in healthcare, future developments on the horizon, and the potential opportunities and pitfalls of these technologies - for both providers and patients.

20.06.2025 19:23 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Screenshot of US-Africa Frontiers of Science Engineering and Medicine webpage.

Screenshot of US-Africa Frontiers of Science Engineering and Medicine webpage.

Bioinformatics is one of the areas covered in this US-Africa Frontiers of Science, Engineering, and Medicine Symposium. Feb 2026. Applications open through July 31, 2025:

www.nationalacademies.org/event/45168_...

04.06.2025 13:23 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
AI in Healthcare: Results Over Hype What is AI in healthcare? How is my doctor using AI? An artificial intelligence expert explains how healthcare is uses AI for patients, medical research.

AI isn’t here to replace your doctorβ€”it’s here to help them spend more time with you. @casey.greenelab.com explains how @cuanschutz.bsky.social researchers are using AI to improve patient care, streamline hospital operations, and build trust through transparency and real-world results.

03.06.2025 15:33 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Post image

Thread: Multi-omics sounds coolβ€”until you actually try it. Here's are the nuances.
1/
You’ve got RNA-seq.
Methylation.
Proteomics.
Time to β€œintegrate” the data.
But how? And why?
Let’s break it down.

19.05.2025 13:21 πŸ‘ 19 πŸ” 4 πŸ’¬ 3 πŸ“Œ 0
Preview
a cartoon of homer simpson and his family in a car with the words are we there yet ALT: a cartoon of homer simpson and his family in a car with the words are we there yet
10.05.2025 13:24 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Wow! Congratulations :)

10.05.2025 13:23 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Open Science Meeting Fund 2025

✴️ Request for proposals! ✴️

@navigation.org is funding focused gatherings to tackle key challenges in Open Science. We support meetings that define solvable problems and quickly move ideas toward implementation.

Deadline: June 15, 2025

os.nav.fund/meeting-fund

#OpenScience

02.05.2025 21:23 πŸ‘ 20 πŸ” 15 πŸ’¬ 2 πŸ“Œ 0
AI for Open Science - Request for Proposals

✴️ REQUEST FOR PROPOSALS! ✴️ @navigation.org is seeking bold projects at the intersection of AI and Open Science. We support innovative applications that make science more transparent, efficient, and trustworthy. Deadline: July 15, 2025. os.nav.fund/ai-for-os/ #openscience #AIforScience

25.04.2025 16:54 πŸ‘ 19 πŸ” 21 πŸ’¬ 0 πŸ“Œ 0
Preview
Science Under Threat in the United States: Research turns hope into reality Two scientists describe how an acute myeloid leukemia diagnosis underscores the need for continued federal support for research and access to care.

Life-saving treatments exist because of decades of research, but cuts to NIH-funded research put that progress at risk.

When the unthinkable happens, will the care we need still be there? We must protect this lifeline.
#StandUpForScience @casey.greenelab.com @annagreene.bsky.social

03.04.2025 15:12 πŸ‘ 5 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Me too!!

27.03.2025 23:00 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Last year, I was surprisingly diagnosed with AML. Attacks on science that we currently face threaten future scientific discoveries that can benefit individuals' health. This should scare us all. Read more about my story and thoughts on this below (with @casey.greenelab.com).

26.03.2025 15:57 πŸ‘ 9 πŸ” 7 πŸ’¬ 0 πŸ“Œ 1

We recently announced new ways to participate in the Open #SingleCell #PediatricCancer Atlas (OpenScPCA) project. Researchers who contribute their expertise may become eligible for a grant! Keep reading for more details about the unique 2025 grant categories. 🧡

17.03.2025 16:11 πŸ‘ 6 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

Excited to see my dissertation work published in Cancer Research @theaacr.bsky.social πŸŽ‰! A big thank you to my chair, Jen Doherty and committee including @casey.greenelab.com for their mentorship on this project! Check out the highlights of our study below if interested πŸ§¬πŸ˜€

11.03.2025 18:19 πŸ‘ 3 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Homepage - openRxiv openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

11.03.2025 13:20 πŸ‘ 2565 πŸ” 847 πŸ’¬ 55 πŸ“Œ 42
Preview
Arc Virtual Cell Atlas launches, combining data from over 300 million cells | Arc Institute Arc Institute today launched the Arc Virtual Cell Atlas, a growing resource for computation-ready single-cell measurements, starting with data from over 300 million cells. The initial release of the A...

Today, we're launching the Arc Virtual Cell Atlas, a growing resource for computation-ready single-cell measurements. arc-website-git-ben-virtual-cell-atlas-tool-arc-institute.vercel.app/news/news/ar...

25.02.2025 14:03 πŸ‘ 39 πŸ” 17 πŸ’¬ 1 πŸ“Œ 3
Preview
Integration of 168,000 samples reveals global patterns of the human gut microbiome The Human Microbiome Compendium is a unified database of publicly available human gut microbiome 16S samples, built with the integrated data from hundreds of independent projects. The compendium is us...

We’re thrilled that our first paper on the Human Microbiome Compendium, an integrated dataset of over 168,000 uniformly processed human gut microbiome samples, is officially out today in Cell! @richabdill.com @blekhman.bsky.social www.cell.com/cell/fulltex...

22.01.2025 17:31 πŸ‘ 100 πŸ” 44 πŸ’¬ 3 πŸ“Œ 6

We did a thing! Read below if you want to learn more :)

22.01.2025 17:41 πŸ‘ 14 πŸ” 1 πŸ’¬ 1 πŸ“Œ 1
Preview
Integration of 168,000 samples reveals global patterns of the human gut microbiome The Human Microbiome Compendium is a unified database of publicly available human gut microbiome 16S samples, built with the integrated data from hundreds of independent projects. The compendium is us...

Today we report a new compendium of human gut microbiomes with >168,000 samples

By analyzing this massive dataset, we discovered distinct microbiome patterns across the globe, and show we can predict where a person lives just from their gut bacteria

Now out in Cell:

www.cell.com/cell/fulltex...

22.01.2025 17:12 πŸ‘ 200 πŸ” 77 πŸ’¬ 10 πŸ“Œ 14

Woo! True credit to @vincerubinetti.bsky.social :)

10.01.2025 15:11 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0