Congrats!! 🥳
10.03.2026 20:15
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Congrats!! 🥳
Recently out: “Uniform dynamics of cohesin-mediated loop extrusion in living human cells”. In this study led by brilliant former PhD student Thomas Sabaté we use live cell microscopy and polymer simulations to characterize how DNA loops and TADs form in human cells by cohesin-driven extrusion. (1/4)
Very excited for this meeting!
We have extended the abstract deadline by a week! Looking forward to seeing you many of you here!
This is a fantastic #biophysics job opportunity to join us in Dresden @mpipks.bsky.social! Apply by the 3rd of April!
Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development!
@karengrace12.bsky.social @nicolettapetridou.bsky.social
🔗 doi.org/10.1242/dev....
We summarised the many roles of material phase transitions in development (and they are not just mechanical 🤔)
Amazing and so well deserved! 🥳🥳
I’m thrilled to share that I will join @gustaveroussy.fr as a Group Leader!
Our objective: to understand how mechanochemical feedbacks regulate tumor dynamics and plasticity, with the overarching goal of bridging tissue mechanobiology and tumor pathophysiology using human organoids.
Best possible lab for a PhD / postdoc! Stay tuned for future openings and wonderful science.
From models to molecules: self-organized and instructed modes of developmental patterning www.nature.com/articles/s41... - nice piece by @davidbrueckner.bsky.social
After being reviewed as a preprint in Elife our paper about endogenous FGF signaling in 2D human gastruloids is now published in Development:
journals.biologists.com/dev/article-...
In a really fun collaboration with Max Wilson’s lab at UCSB, we’ve developed a simple model that can capture the non-monotonic expression of Wnt target genes with respect to frequency in periodic (optogenetic) Wnt pulses: elifesciences.org/articles/107.... Great work Sam, Olivier, Naomi and Ryan :)
New preprint! We show how mesoscopic nonequilibrium fluctuations in active gels emerge from the breaking of detailed balance at the molecular scale. Warning: Long technical paper ahead! Enjoy! @mpipks.bsky.social @ub.edu @ubics.bsky.social @icreacommunity.bsky.social
arxiv.org/abs/2601.20483
Our latest: A gene selection method for single-cell RNA-seq that identifies developmental & spatial patterns missed by other analysis pipelines
ESFS: A Noise-Resilient Framework for Feature Selection and Marker Gene Discovery in Single-Cell Transcriptomics | bioRxiv www.biorxiv.org/content/10.6...
Our review on Marr's levels in embryonic development is now out in @prxlife.bsky.social !
journals.aps.org/prxlife/abst...
Visiting @hhmijanelia.bsky.social just before the winter storm hits! So much awesome science here!
Prof. Fiona Doetsch has been awarded the 2026 Louis-Jeantet Prize for Medicine!
Her discoveries reveal how neural stem cells support lifelong brain plasticity and repair. 🧠
Read more: www.biozentrum.unibas.ch/news/detail/...
Welcome to Basel @robinjournot.bsky.social !! :)
My time at @institutcurie.bsky.social is done! Over the past months, I completed my PhD, published my first first-author paper in DevCell (www.cell.com/developmenta..., and submitted my first last-author manuscript to bioRxiv (www.biorxiv.org/content/10.1...).
Feb 1 deadline approaching for our @kitp-ucsb.bsky.social QBio summer course on Physical Principles of Morphogenesis in Plants and Animals. @streichan.bsky.social
@maurazimmermann.bsky.social @maizel-lab.org @yusuke-mori.bsky.social @akankshi.bsky.social @nicolettapetridou.bsky.social
Interested in the biophysics of organoids? We just published a review in Dev Cell—take a look! dlvr.it/TPyTb8 #Organoids #Biophysics
Self-organized or instructed?
My @natrevgenet.nature.com Journal Club traces how classic papers revealed two modes of developmental patterning & why the debate between Turing and Wolpert is as timely as ever for organoid engineering today
www.nature.com/articles/s41...
And here is the PDF of the 4th course @college-de-france.fr. You will find the justification and presentation of geometric representation of cell decisions, a parsimonious mathematical model for signalling and cell state transitions
tinyurl.com/yc7u296j
Here is the link to download the PDF of my course#5 on Biological computation. I present & discuss Self-tuning, Adaptation and Learning in biological (non-neuronal) systems, in particular during embryonic development.
This course contains various personal ideas/proposals.
tinyurl.com/hcpwsbtm
Please find below the link to watch the VIDEO of my course#5 @college-de-france.fr on Biological computation. I present and discuss Self-tuning, Adaptation and Learning in biological (non/neuronal) systems, in particular during embryonic development.
Enjoy!
tinyurl.com/4pv95an9
Super nice to see this awesome set of lectures online! A really timely perspective on biology through the lens of information, which inspires much of our own research as well.
Munro, E., Nance, J., & Priess, J. R. (2004). Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo. Developmental cell, #EpithelialMechanics www.sciencedirect.com/science/arti...
This was a fun theory collaboration led by amazing postdoc Alex Zhang, in collab with Gasper Tkacik (ISTA)
Throughout this work, we found it really helpful to organize our thinking along 'Marr's three levels of analysis':
1. the computational problem
2. the algorithmic solution
3. biophysical implementation
Check out our review laying out this conceptual framework here: buff.ly/NE4JEOA