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06.06.2025 21:35
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So fascinating.
“As a tracked target approaches the visual midline, the hemisphere about to receive the target shows a ramp-up of activity well before the crossing time, as if it is anticipating the target. Further, activity in the sending hemisphere remains high well after the crossing…”
Such a great song. The Dropkick Murphys do a very respectable cover of it worthy of a listen or two.
“Overall, the findings of the study reignite the discussion on the robustness of the pain pathway’s organization, where multiple mechanisms ensure the persistence of
pain sensation.”
US-based physios who help people in pain: if you are interested in gaining additional support and recognition for the work you do please express your interest in establishing pain rehabilitation as its own distinct clinical specialty area in ABPTS.
umiami.qualtrics.com/jfe/form/SV_...
based on our current understanding of consciousness and development/learning do you suspect we would perceive hunger/thirst differently if, from the moment of our birth, we were supplied with adequate nourishment via IV fluids and TPN?
Thank you Prof Hofer
I’d love to read this but don’t have institutional access. Any chance you have pdf to share? Thank you in advance.
Okay, no worries. Thank you just the same.
I’d love to read this, but I don’t have institutional access. Any chance you could share pdf? Thank you, in advance.
This seems very promising and gives hope to many who are suffering. I’m curious, given your background and expertise what are your thoughts on the premise (growing body of evidence) that endogenous opioids’ primary influence on reducing pain is via regulating affect (vs nociception).
“Resist the urge to find a structural target. Rather, listen carefully, thoughtfully and deeply. Explore their concerns and engage their beliefs. Only once you begin to connect with them on a human level should you start the process of updating their generative model, at a pace of their choosing.”
All of Disintegration since I really have to listen to the entire album to make myself feel complete
I’ve often wondered if it’s more of what I don’t say than what I do say that matters most when helping healthcare consumers improve their understanding of pain and self-management skills.
www.petalcollaboration.org/uploads/1/4/...
Unfortunately, I can’t DM you since you don’t follow me
Would love to read it, but I don’t have access. Any chance you have full text version handy to email? Many thanks.
Analgesia for the Bayesian Brain: How Predictive Coding Offers Insights Into the Subjectivity of Pain
“Ketamine can also alter top-down modulation through psychological dissociation...” Beyond the established anti-nociceptive role opioids play in modulating pain perception, how do we assess the impact of their dissociative effects?
link.springer.com/article/10.1...
you strike me as more of a William Cutting sort of leader - charismatic, principled, but just a bit off…
Thanks so much for creating this. Would love to be added.
Friston’s FEP is, without a doubt, one of the more complex ideas I’ve attempted to comprehend on more than just a superficial level, and I’ve found these papers helpful along the way:
gershmanlab.com/pubs/free_en...
www.mrcbndu.ox.ac.uk/sites/defaul...
I personally enjoy reading a wide variety of writing styles, but they have a point
asmepublications.onlinelibrary.wiley.com/doi/full/10....
Does Active Inference Provide a Comprehensive Theory of Placebo Analgesia?
www.sciencedirect.com/science/arti...
what role might AI serve in our ongoing process of developing more effective care models for helping people in pain?
pmc.ncbi.nlm.nih.gov/articles/PMC...
excellent read if you’re interested in learning more about future directions in cognitive and computational neuroscience
direct.mit.edu/books/oa-mon...
New grad physio reading list:
Aches and Pains - Louis Gifford
Surgery, the Ultimate Placebo - Ian Harris
How Emotions Are Made - Lisa Feldman Barrett
Being You - Anil Seth
Explain Pain Supercharged - Moseley/Butler
The Embodied Mind - Varela, Thompson, Rosch
Two of the more concerning phenomena in healthcare: a surgeon with an open OR and a boat payment to make, and a researcher trying to prove themselves right.
“I know enough to know that I don’t know enough” -mpc