In this observational cohort study of women at risk of acquiring HIV, David Mukasa and colleagues report that initiating HIV preexposure prophylaxis did not associate with an increased incidence of bacterial sexually transmitted infections 🧪 #PrEP #HIV #MedSky
In this target trial emulation study, Shih-Chieh Shao and colleagues investigate the risk of hypomagnesemia in type 2 #diabetes when treated with GLP1-RAs or SGLT2 inhibitors compared to DDP4 inhibitors, using data from the TriNetX global collaborative network 🧪 #T2D #MedSky
plos.io/3NsrnV8
The #COVID-19 pandemic raised concerns about diagnostic delays and treatment disruptions in childhood #cancer. Using national registry data, Kampitsi and colleagues examine patterns in childhood cancer incidence and survival before and during the COVID-19 pandemic in Sweden🧪
plos.io/40fbyUF
Global health architecture is at a structural inflection point. In this Perspective, Ebere Okereke discusses priorities for sustainable progress, including restoring country agency, strengthening national institutions & securing sustainable health financing🧪🌍 #globalhealth #MedSky
plos.io/3N9RiAK
In this genome-wide association study, Richard A Armstrong and colleagues investigate the genetic architecture of postoperative delirium after major surgery and its relationship with related cognitive conditions 🧪🧠🧬 #MedSky
plos.io/4lbRcW3
March is #Endometriosis Awareness Month, and this Editorial by Alex Tosun (@atosun.bsky.social) discusses why greater awareness, education, funding and research for this systemic condition is imperative to redefining pain, equity, and investment in women’s health 🧪🌻 #Medsky
plos.io/4slvscE
This article is accompanied by a Perspective by Giorgia Sulis and Derek MacFadden, which explores behavioral, equity, and governance challenges in tackling #AMR, and how clinical decision support tools can assist in "better, not just fewer" antibiotic prescriptions🧪
plos.io/4skgtjg
In this pragmatic cluster non-randomized trial, Alexandra Kulinkina and colleagues investigate the effectiveness of a clinical decision support algorithm for guiding antibiotic prescribing in pediatric outpatient care in Rwanda 🧪 #MedSky #AMR #antibiotics
plos.io/3MDJiIl
In recognition of Rare Disease Day, this Perspective by Tudor Groza & co discusses how AI can transform rare disease care when organized around patients, outlining a patient-clinician-AI triad spanning diagnosis, clinical trials, & individualized therapies🧪 #RareDiseaseDay
In this study, Qingyu Li and colleagues analyze data from survey responses of an e-consumer cohort in China to understand adherence to event-driven and daily HIV pre-exposure prophylaxis 🧪 #MedSky #HIV #PrEP
plos.io/4cPdI4K
In this modeling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries 🧪 #MedSky #TB
plos.io/4ryyBFX
In this observational study, Jessica Potts and colleagues investigate health inequalities associated with the transitions in kidney therapy modality or death in the UK Renal Registry 🧪 #Medsky
plos.io/4aZlLe2
Conference attendance! PLOS Medicine Senior Editor Alison Farrell (@alisonfarrell.bsky.social) will be attending CROI 2026 in Denver, Colorado, next week. If you want to discuss your research, the journal, Open Access publishing, or more, do reach out and say hi! #CROI2026
Community health workers (CHWs) play a vital role in health services, but remain inadequately compensated. In this Policy Forum article, Temesgen Ayehu &co discuss healthcare reform needed in Sub-Saharan Africa to improve pay & enable integration of CHWs into civil service programs🧪
Air pollution & comorbidities such as hypertension, stroke, and depression are established risk factors for #Alzheimer’s disease (AD). In this study, Yanling Deng & co investigate whether these comorbidities mediate or amplify the effects of fine particulate matter (PM2.5) on AD 🧪🧠
plos.io/4s2zIha
What role should generative artificial intelligence (GAI) play in healthcare? In this Perspective, Arun Thirunavukarasu discusses whether #GAI should be designed to follow treatment guidelines rigidly, provide individualized recommendations, or be somewhere in between 🧪 #AI #Medsky
plos.io/4tDx0jL
In this prospective cohort study, Thomas McDonnell and colleagues examine the relationship of creatinine muscle index (CMI)—an estimate of glomerular filtration of creatinine—with sarcopenia and mortality in a non-dialysis chronic kidney disease population 🧪 #MedSky #CKD
plos.io/4tILvTj
In this modeling study, Natalie Carvalho and colleagues assess the cost-effectiveness of simultaneously introducing rotavirus, pneumococcal conjugate, and human papillomavirus vaccination in the Pacific Island countries Samoa, Tonga, Tuvalu and Vanuatu 🧪 #MedSky
plos.io/4tEMwf9
What are the molecular mediators underlying the link between adiposity & renal cancer? Using evidence from observational & Mendelian randomization analyses, Karine Alcala & co assess obesity‑related risk factors as potential mediators in the development of renal cancer 🧪 #MedSky
In this multi-center, randomized controlled trial, Betina Durovni and colleagues assess the acceptability and safety of a short-course #tuberculosis preventive therapy taken daily or weekly for different durations by persons recently exposed to tuberculosis 🧪 #MedSky #TB
plos.io/4bTs5oh
The Lancet Commission proposed an update in January 2025 on the definition of #obesity. In this observational study, David Lui and colleagues investigate the effect of this new obesity definition on the classification of individuals as overweight in two Chinese cohorts 🧪 #MedSky
plos.io/4aHWg0F
Despite many antihypertensive options, uncontrolled #hypertension remains pervasive. In this Perspective, Luke Laffin & Steven Nissen discuss the promise & challenges of aldosterone synthase inhibitors as the next breakthrough treatment of uncontrolled hypertension🧪 #CVD #MedSky
In recognition of International Day of Women and Girls in STEM, this Editorial by Aparajita Chattopadhyay reflects on the gender gap in #STEM in India, outlining socio-cultural & infrastructural factors, recent promising trends, and what is needed to continue these transformations 🧪
Given recent advancements in digital technology, this systematic review and meta-analysis by Jack Le Vance and colleagues assesses whether teleultrasound is feasible, acceptable, diagnostically accurate and cost effective for antenatal care 🧪 #MedSky
plos.io/4raBqgo
In this study, Cameron M. Gee and colleagues investigated whether targeting spinal cord perfusion pressure via cerebrospinal fluid drainage after acute traumatic spinal cord injury leads to better neurologic recovery than standard mean arterial pressure targets 🧪 #MedSky
plos.io/4tpmoEZ
In this mathematical modeling study, Alvaro Schwalb and colleagues estimate the global burden of viable Mycobacterium tuberculosis—that which can cause disease and be transmitted—to help guide disease prevention efforts 🧪 #tuberculosis #MedSky
plos.io/4aqzIQV
We are deeply saddened by the passing of Professor Sir Nicholas White. His pioneering research transformed malaria treatment worldwide, & his insight & generosity as an Academic Editor were invaluable to PLOS Medicine. Our thoughts are with his family, colleagues, & those whose lives he touched
Optimal glycemic targets for women with gestational diabetes mellitus (GDM) are unclear. In this study, Lisa Douglas & colleagues investigate the effects of different glycemic targets during pregnancy in women with GDM on the health of mothers & their children 🧪 #MedSky
plos.io/4tmvh1V
Abstract deadlines are coming up for the @keystoneSymposia.bsky.social #CancerImmunotherapy meeting this March in Québec.
Learn more about key dates and submission details:
hubs.la/Q03Xlgbv0
#KSCancerImmune26
