Swapnil Hiremath 🍁🇨🇦

Whoah

AI = African Intelligence

(Seems familiar to the Meta moderation workforce, but worse)

Read the whole thing

WKD cake

Celebrating #WorldKidneyDay in Ottawa with a special cake

Kidney Health for All #WKD

💚 Today on World Kidney Day, we urge action to be taken on prevention, awareness, treatment access, and environmental risk reduction. 🌎️ Let's come together to build a healthier, more equitable, and more sustainable future for kidney health. 💚

RFK Jr’s pick to review Covid vaccines authored misleading research, experts say HHS calls MIT professor ‘more than qualified’ for advisory panel and calls ‘attacks’ on him ‘politically motivated’

Is this a correction or what😳

www.nature.com/articles/s41...

Tells you how much journals hate doing retractions 🤷🏽‍♂️

From RFK’s pick to review COVID vaccine safety:

First 6 Days of Iran War Cost U.S. $11.3 Billion, Pentagon Says

The 2026 National Science Foundation budget is $8.75 Billion.

Nicole Kidman - Wikipedia

she's a workaholic who knows that her name attached to something can get it greenlit so she uses that power to uplift women in film promoting original projects.

she is my statuesque botox ozzie queen and I would die for her. en.wikipedia.org/wiki/Nicole_...

I love the idea that *this* US government, which has been nabbing landscapers and five year olds knows where Iranian sleeper cells are but just hasn’t gotten around to doing anything about it yet.

National Cancer Institute has distributed <1% of its annual budget almost halfway through the FY2026. Graph has NCI research grants distributed from Oct 1 to March 12 annually, as per reporter.nih.gov data.
Congress has passed budget to support cancer research. NIH refuses to fight cancer.

It's unlikely that 80% of all labs are stat labs ... I suspect more likely the 6am loop to draw "daily cbc/lytes/creatinine x5" routine labs sucking patients dry for nebulous indications

a cartoon drawing of a hand holding a red stamp Alt: a cartoon drawing of a hand holding a red stamp

Nephrologist approved ✅

splash slide

Happening tomorrow - in person

@pisces01.bsky.social will be presenting at the @uottawa.ca #NephGR

Fish oil for Dialysis

#NephSky

The y-axis is the rate of blood draws that occurred between 4:00 and 7:00 am, per 100 blood draws. The x-axis is the calendar date. Each line corresponds to an individual hospital.

Frequency of early morning blood draws in Ontario hospitals

jamanetwork.com/journals/jam...

early = 4 to 7 AM

The authors point is that disturbs sleep 🛌 (good point) - more delirium, QoL too?

Nephrologist POV: I want labs ASAP, need to make decisions ASAP 🤷‍♂️

#NephSKy #MedSky

Figure one showing more divers with high dose furosemide

Research letter, pilot trial from Mayo ($locked)

pubmed.ncbi.nlm.nih.gov/41802270/

Diuretic resistance is mostly inadequate furosemide dose. Torsemide not needed™️

(Incidence of deafness 🧏🏽‍♂️ not reported)

#NephMadness 2026: POCUS – Stop Guessing, Start Scanning Submit your picks! | @NephMadness | @nephmadness.bsky.social | NephMadness 2026   Abhilash Koratala @NephroP Abhilash Koratala, MD, FASN, FNKF, is a nephrologist–intensivist and Associate Professor…

The first #NephMadness commentary lands - and it suggests POCUS in AKI from Dr POCUS himself

ajkdblog.org/2026/03/10/n...

Which makes me think the Ottawa choice of POCUS in ESRD is right 🤔 though Anna Burgner plays 4D chess 😳

The meds people might get may depend on what their insurance will cover or which one their nephron is most familiar with, or which constellation the moon is in 🤷🏽‍♂️

And less to do with which makes most sense

#NephMadness

And we may never know which one (incl. anti-APRIL only) is best or most effective.

Figure 1. M1 Association With Focal Segmental Glomerulosclerosis (FSGS) or Steroid-Resistant Nephrotic Syndrome (SRNS), Non-FSGS Chronic Kidney Disease (CKD), and Controls in APOL1 High-Risk (HR) Genotypes

An APOL1 variant (M1) that seems to be protective

In JNO from the Columbia Genomics consortium

jamanetwork.com/journals/jam...

Vertex to Seek US Approval After Promising Late-stage Results for Kidney Drug Vertex Pharmaceuticals said on Monday that its experimental drug sharply reduced a key sign of kidney ⁠damage in a late‑stage trial, putting the company on track to seek...

B cell therapies in IgAN advance: povetacicept from Vertex

www.medscape.com/s/viewarticl...

#NephMadness timing was perfect for this

Atacicept has competition now (and there’s the Chinese Telitacicept)

Opinion: Emergency departments are the lighthouses of our health care system. But the lights are starting to flicker ERs are a safety net for those who lack primary care, have substance use disorders or are unhoused. They are meant to be open every hour of every day, no matter what

Emergency departments are the lighthouses of our health care system. But the lights are starting to flicker. They are meant to be open every hour of every day, no matter what, by @casinoshiftmd.bsky.social
www.theglobeandmail.com/opinion/arti... via @theglobeandmail.com

Closest vote: 🐶 versus 🐈🤷🏽‍♂️

Cleanest/unanimous vote: POCUS

Our choices where #BlueRibbonFail is most likely: C3G (Dx over Rx) or Trolls (BKV over CMV)

#NephMadness

More pictures from the Ottawa #NephMadness party

The fellows really did get quite animated for their second bracket 😂

graphical abstract

Preoperative Continuation of RAAS Inhibitors in Hypertensive Patients Undergoing Noncardiac Surgery

🔗 academic.oup.com/ajh/article/... 🔒

Med-Mastodon is Over. Mastodon is still alive. — NephJC Med-Mastodon - the instance - is over

Med-mastodon is going away.

Migrate now if you still have an account there

www.nephjc.com/news/med-mas...

Please vote for the #NephJC kidneys! 🏆
Sign up for the newsletter to get a ballot.
2026 #NephJCKidneys vote begins — NephJC

a close up of a statue of yoda with the words `` patience i have '' written below him . ALT: a close up of a statue of yoda with the words `` patience i have '' written below him .

As much as I love kidney biopsies, still believe we can maximize nephroprotective 💊. So many Q for the phase 3 RCT #nephjc

I sincerely thank all my #NephJC 2025-2026 interns!
This is our last discussion. They are #FOAMed heroes.
We could not do what we do without them. ♥️

a man in a suit says i couldn 't agree more Alt: a man in a suit says i couldn 't agree more

💯 this

#NephJC

Everything said and done, once it reaches clinical practice - implementation is going to be pretty hard, coz the already established treatments are much simpler. And getting a patient to agree to an invasive procedure like a renal biopsy is gonna be next to impossible !
#NephJC

Not sure - even if it works - usage will depend upon
- cost
- if full GDMT (4 pillars) brings down slope of GFR < 1 ml/min/year > then not sure of the added benefit

But this may be a couple of injections and done option vs daily pills?

#NephJC

T3g
In this small study that received 2 doses of REACT the effect was more impressive on GFR slope than SGLT2/GLP1 with only 1.16-1.24 ml/min/1.73m2/year reduction.
If phase 3 trials show similar results, where do you see REACT being used (adjuvant or primary treatment)?
#NephJC