Dmitry Peryshkov

I recently had the opportunity to share my work with @peryshkovinorg.bsky.social at #DiscoverUSC and ended up winning for the morning chemistry section! Additionally, I have completed the requirements for my preparing future faculty (PFF) certification. Very grateful for these awards

Congratulations to Gabby Tellier on winning the @uscresearch.bsky.social SPARC Graduate Research Grant! A well-deserved recognition. @uofsccas.bsky.social

Last week, I had the honor of giving a presentation to a general chemistry class at Claflin University about graduate school and the opportunities that come from it.
youtu.be/0jQ9-SO-upY?...

Cheers to Dr. Amanda Humphries on the successful dissertation defense! The celebration with a spooky twist. Spiders spun the web of success!

N–H Bond Activation of Ammonia by a Redox-Active Carboranyl Diphosphine In this work, we report the room-temperature N–H bond activation of ammonia by the carboranyl diphosphine 1-PtBu2-2-PiPr2-closo-C2B10H10 (1) resulting in the formation of zwitterionic 7-P(NH2)tBu2-10-P(H)iPr2-nido-C2B10H10 (2). Unlike the other phosphorus-based ambiphiles that require geometric constraints to enhance electrophilicity, the new mode of bond activation in this main-group system is based on the cooperation between electron-rich trigonal phosphine centers and the electron-accepting carborane cluster. As an exception among many other metal-based and metal-free systems, the N–H bond activation of gaseous ammonia or aqueous ammonium hydroxide by carboranyl diphosphine 1 proceeds with tolerance of air and water. Mechanistic details of ammonia activation were explored computationally by DFT methods, demonstrating an electrophilic activation of ammonia by the phosphine center. This process is driven by the reduction of the boron cluster followed by an ammonia-assisted deprotonation and proton transfer. A subsequent reaction of 2 and TEMPO results in the cleavage of all N–H and P–H bonds with the formation of a cyclic phosphazenium cation supported by an anionic cluster N(7-PtBu2-8-PiPr2)-nido-C2B9H10 (3). Transformations reported herein represent the first example of ammonia oxidation via triple hydrogen atom abstraction facilitated by a metal-free system.

Now out in JACS: Dmitry Peryshkov and coworkers demonstrate a new metal-free activation of ammonia by a carboranyl diphosphine, with a computational collaboration from our group.

pubs.acs.org/doi/10.1021/...

Prof. François Gabbaï @francoisgabbai.bsky.social delivered an exceptional and inspiring Distinguished Lecture at USC! Fascinating chemistry. Thank you for the visit and discussions.