Anna Panchenko

Cancer histone mutations impact protein binding and DNA repair with possible links to genomic instability Abstract. Histones are key epigenetic factors that regulate the accessibility and compaction of eukaryotic genomes, affecting DNA replication and repair, a

How do histone mutations contribute to cancer development?
Our new study reveals that these mutations impact critical sites where histones interact with DNA or proteins, in some cases disrupting genome maintenance.
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