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Genshiro A. Sunagawa

@genshi.ro

Programmer, scientist, and pediatrician developing human hibernation at RIKEN ๐Ÿปโœจ. I love cooking ๐Ÿณ, programming (Pascal!) ๐Ÿ’ป, and using tech to help others ๐ŸŒ. Lab link: https://bit.ly/3ZpLGEX My book: https://amzn.to/3DGvXHX

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24.11.2024
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Latest posts by Genshiro A. Sunagawa @genshi.ro

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Influence of poly(A) sequences and genetic elements on iCre expression and induction of a hibernation-like state in mice - Journal of Comparative Physiology B Journal of Comparative Physiology B - Activation of hypothalamic QRFP-producing neurons (Q neurons) induces a hibernation-like state in mice, termed Q neuronsโ€“Induced Hypometabolism (QIH). To...

While improving a mouse QIH (synthetic torporโ€“like) model, we found that changing the polyA sequence downstream of a knock-in iCre caused unexpectedly large shifts in expression patterns. A modest observation, but useful for generating mouse lines with brain Cre expression.
doi.org/10.1007/s003...

03.02.2026 07:54 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

An excellent resource for learning both the concepts and practical use of Bayesian statistics, especially for researchers working with real data.

07.01.2026 00:49 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

The major difference this time is that heโ€™s running two parallel tracks each week: Beginner and Experienced. The plan is to cover the entire Statistical Rethinking, 2nd edition by March.

07.01.2026 00:49 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Statistical Rethinking 2026 - Lecture A01 - Introduction to Bayesian Workflow
Statistical Rethinking 2026 - Lecture A01 - Introduction to Bayesian Workflow YouTube video by Richard McElreath

Richard McElreath @rmcelreath.bsky.social has started releasing his new Statistical Rethinking (2026) lectures โ€” I think this is the first update in about three years.
www.youtube.com/watch?v=ztbY...

07.01.2026 00:49 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Statistical Rethinking 2026 - Lecture A01 - Introduction to Bayesian Workflow
Statistical Rethinking 2026 - Lecture A01 - Introduction to Bayesian Workflow YouTube video by Richard McElreath

Richard McElreath ใ•ใ‚“ใฎ ใ€ŽStatistical Rethinking๏ผˆ2026๏ผ‰ใ€ๆ–ฐ่ฌ›็พฉใŒๅ…ฌ้–‹ใ•ใ‚Œๅง‹ใ‚ใŸ๏ผˆ3ๅนดใถใ‚Šใ ใจๆ€ใ†๏ผ‰ใ€‚ไปŠๅ›žใฎๅคงใใช้•ใ„ใฏใ€ Beginner / Experienced ใฎ2ใƒˆใƒฉใƒƒใ‚ฏใ‚’ๆฏŽ้€ฑโ€œไธฆ่ตฐโ€ใ•ใ›ใ‚‹็‚นใ€‚3ๆœˆใพใงใซ Statistical Rethinking 2ed ใ‚’ใ‚ซใƒใƒผใ™ใ‚‹ๆง‹ๆˆใ€‚ใƒ™ใ‚คใ‚บ็ตฑ่จˆใฎๆฆ‚ๅฟตใ‚„ๅฎŸ่ทต็š„ใชๆ‰‹ๆณ•ใ‚’ๅญฆใถใฎใซใจใฆใ‚‚่‰ฏใ„ๆ•™ๆใ ใจๆ€ใ„ใพใ™๏ผ
www.youtube.com/watch?v=ztbY...

07.01.2026 00:44 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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The International Hibernation Society is happy to release the Seasonal Hibernation Highlights for the Fall 2025.

Enjoy reading the latest research on Torpor & Hibernation as Seasonal Adaptative Strategies and as Biomimicry Inspiration!

@sicbjournals.bsky.social @sebiology.bsky.social

27.09.2025 16:10 ๐Ÿ‘ 6 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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The International Hibernation Society starts to release quaterly Seasonal Highlights on the Topic "Torpor & Hibernation as Seasonal Adaptative Strategies".

Here are the first Hibernation Highlights for the Summer 2025. Enjoy reading the latest research from the Torpor & Hibernation field!

18.07.2025 12:18 ๐Ÿ‘ 4 ๐Ÿ” 4 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Quaterly Hibernation Highlights will be available on the IHS Website: hibsoc.com

The PDF of the 2025 Summer Hibernation Highlights are accessible from this link : hibsoc.com/wp-content/u...

Stay Tuned ๐Ÿ˜€ ๐Ÿ™ƒ ๐Ÿ˜

18.07.2025 12:22 ๐Ÿ‘ 2 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Synthetic torpor: advancing metabolic regulation for medical innovations - Nature Metabolism Chen et al. provide an overview of historical and more recent approaches for the induction of synthetic torpor, and discuss their potential medical applications.

Our new review in Nature Metabolism explores the emerging science of synthetic hibernation. From neural circuits to organ protection, mild hypothermia to lifespan modulation. A guide for those venturing into the field.
๐Ÿ‘‰ nature.com/articles/s42...
#SyntheticTorpor #Hibernation #TranslationalMedicine

31.07.2025 14:08 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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These are real images of exoplanets.

Four super-Jupiters, imaged 10 times over 12 years around a star 133 lightyears away.

These are real, giant worlds, out there in the dark.

And we can see them.

07.05.2025 19:57 ๐Ÿ‘ 7858 ๐Ÿ” 1520 ๐Ÿ’ฌ 183 ๐Ÿ“Œ 130
ใ€ใ‚†ใฃใใ‚Š่งฃ่ชฌใ€‘ไบบๅทฅๅ†ฌ็œ ใฎๅฏ่ƒฝๆ€งใ€ ้€ฒๅŒ–่ซ– / ็ง‘ๅญฆ ใ€‘
ใ€ใ‚†ใฃใใ‚Š่งฃ่ชฌใ€‘ไบบๅทฅๅ†ฌ็œ ใฎๅฏ่ƒฝๆ€งใ€ ้€ฒๅŒ–่ซ– / ็ง‘ๅญฆ ใ€‘ YouTube video by ้€ฒๅŒ–็”Ÿ็‰ฉๅญฆchใ€ใ‚†ใฃใใ‚Š่งฃ่ชฌใ€‘

๐ŸŽ‰ Evolutionary Biology Channel featured synthetic hibernation!! โ„๏ธ๐Ÿปโœจ
They explained QIH and its applications so clearlyโ€”I'm super happy! ๐Ÿ˜†๐Ÿ’–
"Hibernation research, standing on the shoulders of giants, will only speed up from here!" ๐Ÿš€๐ŸŒ
#ใ‚†ใฃใใ‚Š่งฃ่ชฌ
www.youtube.com/watch?v=a7c5...

15.02.2025 10:45 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Why we (usually) don't have to worry about multiple comparisons Applied researchers often find themselves making statistical inferences in settings that would seem to require multiple comparisons adjustments. We challenge the Type I error paradigm that underlies t...

Since it is inefficient to attempt to educate every reviewer individually, I am yeeting into your feed this clear paper from Gelman, Hill, and Yajima on how Bayesians can do even better than correcting for multiple comparisons. arxiv.org/abs/0907.2478

26.11.2024 09:11 ๐Ÿ‘ 298 ๐Ÿ” 66 ๐Ÿ’ฌ 17 ๐Ÿ“Œ 5
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ๆ–ฐไฝœใ‚’ใƒชใƒชใƒผใ‚นใ™ใ‚‹ใ“ใจใŒไธ€็•ชใฎๅฎฃไผใ€‚ใฒใจใ‚Šใง7ๅนด้–“๏ผŒใ‚ฒใƒผใƒ ใ‚’ไฝœใฃใฆใใŸๅ€‹ไบบ้–‹็™บ่€…ใŒๅฟƒใŒใ‘ใฆใ„ใŸใ“ใจใจใฏ๏ผปIDC2024๏ผฝ IDC2024ใซใฆใ€Œใฒใจใ‚Šใง7ๅนดใ‚ฒใƒผใƒ ใ‚’ไฝœใฃใฆใใŸ้–‹็™บ่€…ใฎ็”Ÿๅญ˜่ก“ใ€ใจใ„ใ†ใ‚ปใƒƒใ‚ทใƒงใƒณใŒ่กŒใ‚ใ‚ŒใŸใ€‚ใ“ใฎใ‚ปใƒƒใ‚ทใƒงใƒณใฏ๏ผŒๅ€‹ไบบ้–‹็™บ่€…ใฎใ˜ใƒใƒผใพๆฐใŒ่‡ช่บซใฎใ‚ฒใƒผใƒ ้–‹็™บ็ตŒ้จ“ใ‚’ๆŒฏใ‚Š่ฟ”ใฃใฆ๏ผŒๅคงๅˆ‡ใ ใจๆ„Ÿใ˜ใŸใ“ใจใ‚’ๅ…ฑๆœ‰ใ™ใ‚‹ใ‚‚ใฎใ ใ€‚

At IDC2024, solo developer Jiima shared how he uses errors as a tool: by stopping work at a "rough point," errors help him quickly resume tasks. This, along with regular game releases and unified themes, has fueled his success in seven years of solo game development.
www.4gamer.net/games/529/G0...

06.12.2024 00:49 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0