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@scottwilliams9

Geneticist, global health, evolution and human disease, higher education

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16.01.2025
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Latest posts by @scottwilliams9

When I was a student we called our PIs supervisors but they were often more like mentors. Now we call PIs mentors but they are more like supervisors. It's all in the marketing isn't it?

09.03.2026 13:55 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I've lost many university emails - never made a dent

02.03.2026 16:20 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Professor breaks down how a PhD differs from a master's degree in layman's terms A college professor explained how a master’s degree differs from a PhD, and people found her explanation helpful and accessible.

I always try to tell new PhD students many of these things but still they think about classes and grades. And students with a masers can be even more intransigent as have couple more years of same mindset. Of course it is one person's point of view

www.upworthy.com/professor-ex...

02.03.2026 16:19 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The Misuses of the University - Public Books Have the funds that might have trained the next generation of scholars at the nation’s first research university have been blown on ostentatious new buildings?

A depressing picture of the academy in modernity. If ever there was a time for faculty to assert shared governance it is now. If not too late

www.publicbooks.org/the-misuses-...

26.02.2026 04:49 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Deviations from additivity in APOE4-mediated late-onset Alzheimer’s disease risk across races and ethnicities - Human Genetics Human Genetics - APOE’s Ξ΅4 haplotype (APOE4) is late onset Alzheimer’s disease’s (LOAD) strongest genetic risk factor. Therefore, accurately modeling APOE4’s effect is...

Additive genetic models are not always the best and differences seem to exist between populations

sthttps://link.springer.com/article/10.1007/s00439-025-02810-5

22.02.2026 17:53 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

There is a difference between sophistry and science. I wish leaders of our govt agencies overseeing research would take it seriously

21.02.2026 15:29 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Where do we go from here?

19.02.2026 15:46 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

So who defines unsafe?

19.02.2026 15:46 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Could only get through half of this - so many self-inflicted wounds that we will pay for - for many years to come and tracing it back to current policies will be glossed over.

17.02.2026 16:18 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Opinion | A.I. Companies Are Eating Higher Education

www.nytimes.com/2026/02/12/o...

13.02.2026 07:33 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Yep, loved it

03.02.2026 23:56 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Text in paper: "Both HEU and HUU cohorts were recruited from the same hospital during the same enrollment period, with matching criteria detailed in Table S1"
Reviewer: "It is unclear how the HUU was selected – is this the same hospital/region"
Becoming the norm - maybe unreviewed papers are better?

03.02.2026 18:43 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Yep. Fun, fun

01.02.2026 22:22 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

In modern science education we too often we learn how to do things not how to question what we do. As scientists we too often are judged by how much we do, not what we do. This is a perverse system of metrics that slows development of knowledge

01.02.2026 18:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

"It’s one of the real black marks on the history of higher education that an entire industry that’s supposedly populated by the best minds in the countryβ€”theoretical physicists, writers, criticsβ€”is bamboozled by a third-rate news magazine"
Leon Botstein on college rankings, The New Yorker 2014

30.01.2026 16:03 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Has anyone else had a paper on medrxiv been sent out for review after a predatory journal reached out? We did not agree to submit it as it is under revision elsewhere, but we were sent an unsolicited review from the aforementioned journal. Very unethical!!

30.01.2026 02:59 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Opposing effects of SARS-CoV-2/COVID-19 infection and recombinant zoster vaccination on the risk of late-onset Alzheimer disease Abstract Importance More than half a decade since the emergence of SAR-CoV-2, its broader sequelae are still poorly understood. Initial data indicate viral infections such as SARS-CoV-2 and herpes zos...

www.medrxiv.org/content/10.6...

27.01.2026 16:19 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Is it time to re-read "On Bullsh*t" by Harry Frankfurt. The world he pictures has only gotten bleaker

27.01.2026 14:34 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Of course - just pushing the extreme

26.01.2026 17:07 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Is AI the only thing we all should ve working on if we want to preserve humanity

26.01.2026 15:46 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

If we are concerned about future of humanity maybe AI research and how it plays out is all we should be working on, if we can

26.01.2026 15:45 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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AI models collapse when trained on recursively generated data - Nature  Analysis shows that indiscriminately training generative artificial intelligence on real and generated content, usually done by scraping data from the Internet, can lead to a collapse in th...

Ooops
www.nature.com/articles/s41...

26.01.2026 05:05 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The best you've posted to date!

25.01.2026 17:37 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Funny in a perverse way. Just check what you submit, please

23.01.2026 13:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Deviations from additivity in APOE4-mediated late-onset Alzheimer’s disease risk across races and ethnicities - Human Genetics Human Genetics - APOE’s Ξ΅4 haplotype (APOE4) is late onset Alzheimer’s disease’s (LOAD) strongest genetic risk factor. Therefore, accurately modeling APOE4’s effect is...

ApoE4 effect on Alzheimer is not always additive and the deviation from additivity varies by race and ethnicity - ot in Human Genetics

link.springer.com/article/10.1...

22.01.2026 16:34 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Has Corporatization Met Its Match? The Challenge of Making Money by Keeping People Healthy | NEJM Corporatization exacerbates the problem of perverse incentives for health care organizations, pitting profits against health maintenance. How could delivering health become a sustainable business?

Has Corporatization Met Its Match? The Challenge of Making Money by Keeping People Healthy | New England Journal of Medicine www.nejm.org/doi/full/10....

11.01.2026 19:15 πŸ‘ 5 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Is tis real? If so, then we are in big trouble.

09.01.2026 15:25 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

WTF. Write a book for you? The more technology X and help the more dreck produced?

02.01.2026 16:30 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

When I was young, was told by teachers that it is the quality not the quantity. A short excellent essay outweighs a long but uniformed one. Forward decades and metrics among scientists is how many papers you publish (coauthor) or how much data you can collect not the knowledge advanced. A bad change

31.12.2025 15:51 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

If half of this is true we are completely screwed as a society. Where is the responsibility of actually doing the assignment?
And calling the prof mentally ill - again if true this should be actionable

30.12.2025 16:45 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0