Chris Rybak

Any note on the enolate selectivity in the first step? I’ve used a similar way to make 2-ethyl naphthyridine, but got a 1:1 mixture with 2,3-dimethyl naphthyridine

Little minigame you need to do so you can get a spectrum

Eating an uncrustable while ironing a shirt for the first time feels like a peak night before your Defense experience

I ordered some from Thermo back in December, finally got it last month. Ordered another bottle, we’ll see how long it takes this time

I think I remember using that for pchem lab like 8 years ago

So is it too late to join the apply for postdocs in Europe bandwagon?

Shakes ain’t bad though

Dicobalt-catalyzed N=N coupling reactions of tertiary alkyl azides to form azoalkanes Azoalkanes can serve as radical precursors for various catalytic and stoichiometric C–C bond-forming reactions. However, their use in these processes …

Congrats to Mankad Group alum Kyle Brook and his teammates in the Uyeda lab for their fantastic paper in @cp-chem.bsky.social #chemsky
www.sciencedirect.com/science/arti...

Very nice work, Mingxin from our lab was happy to see the advancement of the Ni cyclopropanation chemistry

Sure is hard to get out of bed when it’s like -20° out and your cat is on top of you

What’s the proton look like, a bar code?

I’ve grown plenty of crystals for XRD of metal complexes using vapor diffusion and evaporation, but somehow struggle with larger scale organic compounds. I think I’m just less patient for stuff outside the glovebox

Recrysts are a technique I’ve always wanted to improve on. I feel like it’s so intuition based, but I just haven’t cracked it yet

Any place that sells donuts and fried chicken all day is *chefs kiss*

I barely had it in me to take one more NMR after cleaning the rotovap bath

Two mistakes, a cracked ground glass joint on the bump trap, and letting go before vacuum to fill the cold finger with dry ice

Minimum motivation is dropping a 5 gram reaction into the rotovap bath on your last day before the holiday break #chemsky

Bring a sixth year is definitely an experience. All the first years look at you funny at the bars

Went from ligand synthesis being the hardest part of my last project, to all my substrates being compounds used as ligands in my new project. The chemistry gods can be cruel

Uhhh Boiler Up I guess?

Ope forgot the #ChemSky

Was mostly a lurker on the Other Place but I’ll try my best to shake that here. I’m an organic/organometallic chemistry grad student in the Uyeda lab at Purdue University where I’ve spent my PhD synthesizing azoarenes using dinickel catalysts. Down to talk chemistry, hockey, and most things nerdy

Is it a bottle you keep on the bench, or some that’s fairly anhydrous?

This is what I was going to mention. We’ve got a reaction in our lab that works great if you use the pure boroxine, but not at all with the acid/boroxine mixture

That’s what we do in our lab, convert the rest of the alkene to the epoxide

At what point does one stop adding cool substrates to their scope? Asking for a friend who’s gone from 25 to 50 in a few months and really wants to graduate eventually

Love my fluorinated substrates for 19F, absolutely hate them for every other nuclei